Fkbp6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Fkbp6
Entrez Gene ID	288597
Full Name	FK506 binding protein 6
Synonyms	FKBP-36,PPiase
General protein information	Preferred Names FK506 binding protein 6 Names inactive peptidyl-prolyl cis-trans isomerase FKBP6 36 kDa FK506 binding protein FK506 binding protein 6, 36kDa immunophilin FKBP36 inactive PPIase FKBP6 peptidyl-prolyl cis-trans isomerase FKBP6 rotamase
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 12 Map Location: 12q12

mRNA and Protein(s)

mRNA	Protein	Name
NM_001105922.1	NP_001099392.1	inactive peptidyl-prolyl cis-trans isomerase FKBP6
XM_008769130.2	XP_008767352.1	inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform X1
XM_017598299.1	XP_017453788.1	inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform X1
XM_006249131.3	XP_006249193.1	inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform X2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	FKBP6	XP_003318729.1
Mus musculus (house mouse)	Fkbp6	NP_291049.1
	FKBP6	XP_001110932.1
Rattus norvegicus (Norway rat)	Fkbp6	NP_001099392.1
Drosophila melanogaster (fruit fly)	shu	NP_611837.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011458	XP_001237981.2
Bos taurus (cattle)	FKBP6	NP_001095679.1
Danio rerio (zebrafish)	fkbp6	NP_001122145.1
Xenopus tropicalis (tropical clawed frog)	fkbp6	NP_989052.1
Homo sapiens (human)	FKBP6	NP_003593.3
Canis lupus familiaris (dog)	FKBP6	XP_546928.2
Gallus gallus (chicken)	FKBP6	XP_415708.4

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of FKBP6 in hepatitis C virus replication.
Kasai H, Kawakami K, Yokoe H, Yoshimura K, Matsuda M, Yasumoto J, Maekawa S, Yamashita A, Tanaka T, Ikeda M, Kato N, Okamoto T, Matsuura Y, Sakamoto N, Enomoto N, Takeda S, Fujii H, Tsubuki M, Kusunoki M, Moriishi K
Scientific reports516699(2015 Nov)

A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.
Xiol J, Cora E, Koglgruber R, Chuma S, Subramanian S, Hosokawa M, Reuter M, Yang Z, Berninger P, Palencia A, Benes V, Penninger J, Sachidanandam R, Pillai RS
Molecular cell47(6)970-9(2012 Sep)

Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency.
Noguchi J, Ozawa M, Nakai M, Somfai T, Kikuchi K, Kaneko H, Kunieda T
The Journal of reproduction and development54(3)203-7(2008 Jun)

Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.
Crackower MA, Kolas NK, Noguchi J, Sarao R, Kikuchi K, Kaneko H, Kobayashi E, Kawai Y, Kozieradzki I, Landers R, Mo R, Hui CC, Nieves E, Cohen PE, Osborne LR, Wada T, Kunieda T, Moens PB, Penninger JM
Science (New York, N.Y.)300(5623)1291-5(2003 May)

A novel human gene FKBP6 is deleted in Williams syndrome.
Meng X, Lu X, Morris CA, Keating MT
Genomics52(2)130-7(1998 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

fundamental role of Fkbp6 in homologous chromosome synapsis during male meiosis
Title: Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency.

Fkbp6 is a component of the synaptonemal complex essential for sex-specific fertility and for the fidelity of homologous chromosome pairing in meiosis.
Title: Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.

The following Fkbp6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fkbp6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa13091	NM_001105922.1 Latest version!	Rattus norvegicus FKBP prolyl isomerase 6 (Fkbp6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa13091	XM_008769130.2 Latest version!	Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa13091	XM_017598299.1 Latest version!	Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
ORa34753	XM_006249131.3 Latest version!	Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Fkbp6 ( NM_001105922.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099392.1 Rattus norvegicus FKBP prolyl isomerase 6 (Fkbp6), mRNA.

Price & Availability↑

CloneID	ORa13091
Clone ID Related Accession (Same CDS sequence)	NM_001105922.1 , XM_008769130.2 , XM_017598299.1
Accession Version	NM_001105922.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	inactive peptidyl-prolyl cis-trans isomerase FKBP6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473973.1. On or before Oct 3, 2007 this sequence version replaced XM_222082.3, XM_001071214.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689604, SAMN02642705 [ECO:0000348] ##Evidence-Data-END##

ATGAGTGTCT TCTCGCGCCT CAGGAACGGA ATCCCACCGT CGCGAGACGA CTGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099392.1
CDS	35..1018
Translation	MSVFSRLRNGIPPSRDDCQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN

Target ORF information:

RefSeq Version	NM_001105922.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FKBP prolyl isomerase 6 (Fkbp6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001105922.1

ORF Insert Sequence:

ATGAGTGTCT TCTCGCGCCT CAGGAACGGA ATCCCACCGT CGCGAGACGA CTGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp6 ( XM_008769130.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008767352.1 Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa13091
Clone ID Related Accession (Same CDS sequence)	NM_001105922.1 , XM_008769130.2 , XM_017598299.1
Accession Version	XM_008769130.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769130.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGTCT TCTCGCGCCT CAGGAACGGA ATCCCACCGT CGCGAGACGA CTGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008767352.1
CDS	155..1138
Translation	MSVFSRLRNGIPPSRDDCQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN

Target ORF information:

RefSeq Version	XM_008769130.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008769130.2

ORF Insert Sequence:

ATGAGTGTCT TCTCGCGCCT CAGGAACGGA ATCCCACCGT CGCGAGACGA CTGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp6 ( XM_017598299.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017453788.1 Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa13091
Clone ID Related Accession (Same CDS sequence)	NM_001105922.1 , XM_008769130.2 , XM_017598299.1
Accession Version	XM_017598299.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGTGTCT TCTCGCGCCT CAGGAACGGA ATCCCACCGT CGCGAGACGA CTGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017453788.1
CDS	155..1138
Translation	MSVFSRLRNGIPPSRDDCQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN

Target ORF information:

RefSeq Version	XM_017598299.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017598299.1

ORF Insert Sequence:

ATGAGTGTCT TCTCGCGCCT CAGGAACGGA ATCCCACCGT CGCGAGACGA CTGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Fkbp6 ( XM_006249131.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006249193.1 Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa34753
Clone ID Related Accession (Same CDS sequence)	XM_006249131.3
Accession Version	XM_006249131.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 984bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	inactive peptidyl-prolyl cis-trans isomerase FKBP6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006249131.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGGTA GCACCCGAGG CCGGGGAGCC CTGGAAGGGG ACGACGTCCT AGGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006249193.1
CDS	54..1037
Translation	MGGSTRGRGALEGDDVLGQSPYERLSQRMLDISGDRGVLKDIIREGAGDPVTPDASVLVKYSGYLEHMDKPFDSNCFRKTPRLMKLGEDITLWGMELGLLSMRRGELARFLFKPTYAYGTLGCPPLIPPNATVLFEIELIDFLDSAESDKFCALSAEQQEQFPLQKVLKVAATEREFGNYLFRQNRFCDAKVRYKRALLLLHRRLAICEEQHLVEPAELLVLLNLSFVYLKLDRPAMALRYGEQALLIDKRNAKALFRCGQACLLLTEYEQARDFLVRAQKEQPCNHDINNELKKLSSHYRDYVDREREMCHRMFAPCGSGSSVGGN

Target ORF information:

RefSeq Version	XM_006249131.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus FK506 binding protein 6 (Fkbp6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006249131.3

ORF Insert Sequence:

ATGGGTGGTA GCACCCGAGG CCGGGGAGCC CTGGAAGGGG ACGACGTCCT AGGCCAGTCT 
CCCTATGAGC GATTAAGTCA ACGCATGTTG GACATTTCTG GGGACCGAGG TGTGCTGAAA 
GATATCATCC GCGAGGGCGC TGGCGATCCT GTGACACCTG ACGCTTCTGT GCTGGTGAAA 
TACTCTGGAT ACCTGGAGCA CATGGATAAG CCTTTCGACT CCAATTGCTT TAGGAAAACC 
CCTCGGCTGA TGAAACTTGG AGAAGATATT ACACTCTGGG GCATGGAGCT GGGCCTTCTA 
AGCATGCGCA GAGGGGAACT GGCCAGGTTC CTGTTCAAGC CAACCTATGC TTATGGTACC 
CTGGGGTGCC CGCCCCTCAT CCCTCCAAAT GCCACTGTCC TGTTTGAGAT CGAGCTGATT 
GACTTCCTGG ACTCTGCCGA GTCGGACAAG TTTTGTGCAC TCTCAGCTGA GCAGCAAGAA 
CAGTTTCCAC TCCAGAAAGT CCTCAAGGTA GCGGCAACCG AGAGGGAGTT TGGCAACTAC 
CTTTTCCGCC AGAATCGCTT CTGTGATGCC AAAGTGAGAT ACAAGCGGGC CTTGTTGCTG 
CTCCATCGAC GCTTGGCCAT CTGTGAGGAG CAGCACTTGG TAGAACCTGC TGAGCTCCTA 
GTCCTCCTTA ACCTTTCATT TGTGTACCTG AAGCTAGACC GCCCTGCTAT GGCCCTGCGC 
TATGGGGAGC AGGCTCTGCT CATTGACAAA AGGAACGCCA AAGCCCTCTT CAGGTGTGGA 
CAGGCTTGCC TCCTCCTGAC CGAGTATGAG CAGGCTCGGG ACTTTCTAGT GAGAGCTCAG 
AAGGAGCAGC CCTGTAACCA TGACATCAAT AATGAGCTGA AGAAGCTGTC CAGCCACTAC 
AGGGACTATG TGGACAGAGA GAGAGAGATG TGTCACCGGA TGTTTGCTCC CTGTGGAAGC 
GGCTCTTCAG TGGGAGGAAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of FKBP6 in hepatitis C virus replication.
Scientific reports516699(2015 Nov)
Kasai H,Kawakami K,Yokoe H,Yoshimura K,Matsuda M,Yasumoto J,Maekawa S,Yamashita A,Tanaka T,Ikeda M,Kato N,Okamoto T,Matsuura Y,Sakamoto N,Enomoto N,Takeda S,Fujii H,Tsubuki M,Kusunoki M,Moriishi K

A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.
Molecular cell47(6)970-9(2012 Sep)
Xiol J,Cora E,Koglgruber R,Chuma S,Subramanian S,Hosokawa M,Reuter M,Yang Z,Berninger P,Palencia A,Benes V,Penninger J,Sachidanandam R,Pillai RS

Affected homologous chromosome pairing and phosphorylation of testis specific histone, H2AX, in male meiosis under FKBP6 deficiency.
The Journal of reproduction and development54(3)203-7(2008 Jun)
Noguchi J,Ozawa M,Nakai M,Somfai T,Kikuchi K,Kaneko H,Kunieda T

Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis.
Science (New York, N.Y.)300(5623)1291-5(2003 May)
Crackower MA,Kolas NK,Noguchi J,Sarao R,Kikuchi K,Kaneko H,Kobayashi E,Kawai Y,Kozieradzki I,Landers R,Mo R,Hui CC,Nieves E,Cohen PE,Osborne LR,Wada T,Kunieda T,Moens PB,Penninger JM

A novel human gene FKBP6 is deleted in Williams syndrome.
Genomics52(2)130-7(1998 Sep)
Meng X,Lu X,Morris CA,Keating MT

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Fkbp6 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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