Gene Symbol | Iscu |
Entrez Gene ID | 288740 |
Full Name | iron-sulfur cluster assembly enzyme |
Synonyms | RGD1309562 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Iscu cDNA ORF clone
gRNAs
Gene Symbol | Iscu |
Entrez Gene ID | 288740 |
Full Name | iron-sulfur cluster assembly enzyme |
Synonyms | RGD1309562 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001105936.1 | NP_001099406.1 | iron-sulfur cluster assembly enzyme ISCU, mitochondrial |
Pan troglodytes (chimpanzee) | ISCU | XP_509343.2 |
Canis lupus familiaris (dog) | LOC477527 | XP_534722.1 |
Mus musculus (house mouse) | Iscu | NP_079802.1 |
Drosophila melanogaster (fruit fly) | CG9836 | NP_649840.1 |
Oryza sativa (rice) | Os01g0662600 | NP_001043783.1 |
Oryza sativa (rice) | Os05g0568100 | NP_001056355.1 |
Xenopus tropicalis (tropical clawed frog) | iscu | NP_989088.1 |
Bos taurus (cattle) | ISCU | NP_001069151.1 |
Danio rerio (zebrafish) | iscub | NP_001017800.2 |
Caenorhabditis elegans (roundworm) | Y45F10D.4 | NP_502658.1 |
Saccharomyces cerevisiae (baker's yeast) | ISU1 | NP_015190.1 |
Danio rerio (zebrafish) | si:ch211-191d15.2 | NP_001003632.1 |
Saccharomyces cerevisiae (baker's yeast) | ISU2 | NP_014869.3 |
Eremothecium gossypii | AGOS_ACR112C | NP_983514.1 |
Neurospora crassa | NCU05778 | XP_960038.1 |
Homo sapiens (human) | ISCU | NP_998760.1 |
Rattus norvegicus (Norway rat) | Iscu | NP_001099406.1 |
Gallus gallus (chicken) | ISCU | XP_003642230.2 |
Arabidopsis thaliana (thale cress) | ISU1 | NP_193953.1 |
Arabidopsis thaliana (thale cress) | ISU2 | NP_186751.1 |
ISCU | XP_001103180.1 | |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005813 | XP_315834.2 |
Kluyveromyces lactis | KLLA0D07161g | XP_453380.1 |
Schizosaccharomyces pombe (fission yeast) | isu1 | NP_592967.1 |
Arabidopsis thaliana (thale cress) | ISU3 | NP_192317.1 |
Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly.
Shan Y, Cortopassi G
Mitochondrion2694-103(2016 Jan)
Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery.
Maio N, Rouault TA
Biochimica et biophysica acta1853(6)1493-512(2015 Jun)
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU.
Favaro E, Ramachandran A, McCormick R, Gee H, Blancher C, Crosby M, Devlin C, Blick C, Buffa F, Li JL, Vojnovic B, Pires das Neves R, Glazer P, Iborra F, Ivan M, Ragoussis J, Harris AL
PloS one5(4)e10345(2010 Apr)
Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues.
Martelli A, Wattenhofer-Donz? M, Schmucker S, Bouvet S, Reutenauer L, Puccio H
Human molecular genetics16(22)2651-8(2007 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Iscu gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Iscu cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11697 | |
Clone ID Related Accession (Same CDS sequence) | NM_001105936.1 | |
Accession Version | NM_001105936.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 504bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | iron-sulfur cluster assembly enzyme ISCU, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473973.1. On or before Oct 3, 2007 this sequence version replaced XM_001078081.1, XM_213811.4. ##Evidence-Data-START## Transcript exon combination :: BC167056.1, CF108498.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297, SAMN01906356 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCGGCGG CTGGAGCGGG CCGTCTGAGG CGGGCGGCGT CCGCGCTGCT GCTCCGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099406.1 |
CDS | 42..545 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCGGCGG CTGGAGCGGG CCGTCTGAGG CGGGCGGCGT CCGCGCTGCT GCTCCGGAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mitochondrial Hspa9/Mortalin regulates erythroid differentiation via iron-sulfur cluster assembly. |
Iron-sulfur cluster biogenesis in mammalian cells: New insights into the molecular mechanisms of cluster delivery. |
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU. |
Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues. |