Gene Symbol | Chit1 |
Entrez Gene ID | 289032 |
Full Name | chitinase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Chit1 cDNA ORF clone
Gene Symbol | Chit1 |
Entrez Gene ID | 289032 |
Full Name | chitinase 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_008769542.2 | XP_008767764.1 | chitotriosidase-1 isoform X2 |
XM_008769542.1 | XP_008767764.1 | chitotriosidase-1 isoform X1 |
NM_001270846.1 | NP_001257775.1 | chitotriosidase-1 precursor |
NM_001079689.2 | NP_001073157.1 | chitotriosidase-1 precursor |
NM_001270848.1 | NP_001257777.1 | chitotriosidase-1 precursor |
XM_017598698.1 | XP_017454187.1 | chitotriosidase-1 isoform X1 |
NM_001270847.1 | NP_001257776.1 | chitotriosidase-1 precursor |
Pan troglodytes (chimpanzee) | CHIT1 | XP_001155147.2 |
Rattus norvegicus (Norway rat) | Chit1 | NP_001257775.1 |
Arabidopsis thaliana (thale cress) | AT4G19730 | NP_193708.1 |
Arabidopsis thaliana (thale cress) | AT4G19820 | NP_193717.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006898 | XP_308858.4 |
Magnaporthe oryzae (rice blast fungus) | MGG_05533 | XP_003710401.1 |
Arabidopsis thaliana (thale cress) | AT4G19810 | NP_193716.1 |
Arabidopsis thaliana (thale cress) | AT4G19740 | NP_193709.3 |
Xenopus tropicalis (tropical clawed frog) | chit1 | NP_001005792.1 |
Homo sapiens (human) | CHIT1 | NP_003456.1 |
Caenorhabditis elegans (roundworm) | cht-1 | NP_508588.1 |
Arabidopsis thaliana (thale cress) | AT4G19720 | NP_193707.2 |
Arabidopsis thaliana (thale cress) | AT4G19760 | NP_193711.2 |
Arabidopsis thaliana (thale cress) | AT4G19770 | NP_193712.2 |
Drosophila melanogaster (fruit fly) | Cht7 | NP_647768.3 |
Arabidopsis thaliana (thale cress) | AT4G19750 | NP_193710.2 |
Oryza sativa (rice) | Os11g0462100 | NP_001067864.1 |
CHIT1 | XP_001103012.1 | |
Bos taurus (cattle) | CHIT1 | XP_003587088.2 |
Mus musculus (house mouse) | Chit1 | NP_001271454.1 |
Arabidopsis thaliana (thale cress) | AT4G19800 | NP_193715.1 |
Oryza sativa (rice) | Os04g0376400 | NP_001052581.1 |
New paralogues and revised time line in the expansion of the vertebrate GH18 family.
Hussain M, Wilson JB
Journal of molecular evolution76(4)240-60(2013 Apr)
Congenic mapping and sequence analysis of the Renin locus.
Flister MJ, Hoffman MJ, Reddy P, Jacob HJ, Moreno C
Hypertension (Dallas, Tex. : 1979)61(4)850-6(2013 Apr)
Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised rats.
Verwer PE, ten Kate MT, Falcone FH, Morroll S, Verbrugh HA, Bakker-Woudenberg IA, van de Sande WW
PloS one8(10)e75848(2013)
Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates.
Bussink AP, Verhoek M, Vreede J, Ghauharali-van der Vlugt K, Donker-Koopman WE, Sprenger RR, Hollak CE, Aerts JM, Boot RG
The FEBS journal276(19)5678-88(2009 Oct)
Molecular cloning and characterization of rat chitotriosidase.
Chen XH, Cai GP
DNA sequence : the journal of DNA sequencing and mapping19(2)121-9(2008 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Invasive pulmonary aspergillosis in immunocompromised rats caused a dramatic increase in chitinase activity.
Title: Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised rats.
Expression of cloned cDNA of chitotriosidase demonstrates that the encoded protein is secreted extracellularly and has chitinolytic activity.
Title: Molecular cloning and characterization of rat chitotriosidase.
The following Chit1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chit1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10470 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270846.1 , NM_001079689.2 , NM_001270848.1 , XM_017598698.1 , NM_001270847.1 | |
Accession Version | NM_001270846.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117152.5. Transcript Variant: This variant (bChiV_4) differs in the 5' UTR compared to variant bChiV_5. All four variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DQ923319.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257775.1 |
CDS | 233..1627 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270846.1 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa10470 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270846.1 , NM_001079689.2 , NM_001270848.1 , XM_017598698.1 , NM_001270847.1 | |
Accession Version | NM_001079689.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117152.5. On Aug 3, 2012 this sequence version replaced NM_001079689.1. Transcript Variant: This variant (bChiV_5) represents the longest transcript. All four variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DQ923320.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689603, SAMEA2689604 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001073157.1 |
CDS | 584..1978 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001079689.2 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa10470 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270846.1 , NM_001079689.2 , NM_001270848.1 , XM_017598698.1 , NM_001270847.1 | |
Accession Version | NM_001270848.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07020988.1 and AC117152.5. Transcript Variant: This variant (bChiV_2) differs in the 5' UTR compared to variant bChiV_5. All four variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DQ923317.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257777.1 |
CDS | 217..1611 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270848.1 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa10470 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270846.1 , NM_001079689.2 , NM_001270848.1 , XM_017598698.1 , NM_001270847.1 | |
Accession Version | NM_001270847.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC117152.5. Transcript Variant: This variant (bChiV_3) differs in the 5' UTR compared to variant bChiV_5. All four variants encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DQ923318.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642718 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257776.1 |
CDS | 132..1526 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270847.1 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa10470 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270846.1 , NM_001079689.2 , NM_001270848.1 , XM_017598698.1 , NM_001270847.1 | |
Accession Version | XM_017598698.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1395bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017454187.1 |
CDS | 435..1829 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017598698.1 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGTGTG ACGACTCTGC TGATGATCCA GTGGGGCTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa44743 | |
Clone ID Related Accession (Same CDS sequence) | XM_008769542.2 , XM_008769542.1 | |
Accession Version | XM_008769542.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008769542.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGCTCT GCTGCAAAAC TGTTCTGCTA CTTCACCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008767764.1 |
CDS | 211..1575 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008769542.2 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGCTCT GCTGCAAAAC TGTTCTGCTA CTTCACCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa44743 | |
Clone ID Related Accession (Same CDS sequence) | XM_008769542.2 , XM_008769542.1 | |
Accession Version | XM_008769542.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1365bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2014-08-06 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chitotriosidase-1 isoform X1 | |
Comment |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGCTCT GCTGCAAAAC TGTTCTGCTA CTTCACCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008767764.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008769542.1 |
1 | ATGGTGCAGT CCCTGGCCTT GGCAGGCTCT GCTGCAAAAC TGTTCTGCTA CTTCACCAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
New paralogues and revised time line in the expansion of the vertebrate GH18 family. |
Congenic mapping and sequence analysis of the Renin locus. |
Evidence supporting a role for mammalian chitinases in efficacy of caspofungin against experimental aspergillosis in immunocompromised rats. |
Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates. |
Molecular cloning and characterization of rat chitotriosidase. |