Gene Symbol | Nuak2 |
Entrez Gene ID | 289419 |
Full Name | NUAK family kinase 2 |
Synonyms | 1200013b22rik,Snark,UV126 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Nuak2 cDNA ORF clone
Gene Symbol | Nuak2 |
Entrez Gene ID | 289419 |
Full Name | NUAK family kinase 2 |
Synonyms | 1200013b22rik,Snark,UV126 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_008769444.1 | XP_008767666.1 | NUAK family SNF1-like kinase 2 isoform X1 |
NM_001007617.1 | NP_001007618.1 | NUAK family SNF1-like kinase 2 |
Gallus gallus (chicken) | NUAK2 | XP_004934986.1 |
Xenopus tropicalis (tropical clawed frog) | nuak2 | NP_001121499.1 |
Homo sapiens (human) | NUAK2 | NP_112214.1 |
Rattus norvegicus (Norway rat) | Nuak2 | NP_001007618.1 |
Canis lupus familiaris (dog) | NUAK2 | XP_545687.2 |
Mus musculus (house mouse) | Nuak2 | NP_001181954.1 |
Danio rerio (zebrafish) | nuak2 | XP_688764.3 |
Pan troglodytes (chimpanzee) | NUAK2 | XP_003308757.1 |
NUAK2 | XP_001088883.2 |
Regulation of ploidy and senescence by the AMPK-related kinase NUAK1.
Humbert N, Navaratnam N, Augert A, Da Costa M, Martien S, Wang J, Martinez D, Abbadie C, Carling D, de Launoit Y, Gil J, Bernard D
The EMBO journal29(2)376-86(2010 Jan)
Regulation of SNARK activity in response to cellular stresses.
Lefebvre DL, Rosen CF
Biochimica et biophysica acta1724(1-2)71-85(2005 Jun)
Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness.
Legembre P, Schickel R, Barnhart BC, Peter ME
The Journal of biological chemistry279(45)46742-7(2004 Nov)
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.
Lizcano JM, G?ransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, M?kel? TP, Hardie DG, Alessi DR
The EMBO journal23(4)833-43(2004 Feb)
Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family.
Suzuki A, Kusakai G, Kishimoto A, Minegichi Y, Ogura T, Esumi H
Biochemical and biophysical research communications311(1)156-61(2003 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
SNARK (SNF1/AMP-activated protein kinase) activity is regulated by a broad range of cellular stresses in a cell-type-specific manner.
Title: Regulation of SNARK activity in response to cellular stresses.
The following Nuak2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nuak2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11181 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007617.1 | |
Accession Version | NM_001007617.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1893bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | NUAK family SNF1-like kinase 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081899.1. On Nov 29, 2004 this sequence version replaced XM_223108.2. ##Evidence-Data-START## Transcript exon combination :: BC081899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGAGTCGG TGGCCTTACA CCGGCGCGGG AACCTGGCTC CCTCGGCCTC CGCCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001007618.1 |
CDS | 73..1965 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001007617.1 |
1 | ATGGAGTCGG TGGCCTTACA CCGGCGCGGG AACCTGGCTC CCTCGGCCTC CGCCCTGGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa44795 | |
Clone ID Related Accession (Same CDS sequence) | XM_008769444.1 | |
Accession Version | XM_008769444.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | NUAK family SNF1-like kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005112.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTTCAC TCAACCACCC CCACATCATT GCCATCCATG AAGTGTTTGA GAACAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008767666.1 |
CDS | 1095..2666 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008769444.1 |
1 | ATGTCTTCAC TCAACCACCC CCACATCATT GCCATCCATG AAGTGTTTGA GAACAGCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Regulation of ploidy and senescence by the AMPK-related kinase NUAK1. |
Regulation of SNARK activity in response to cellular stresses. |
Identification of SNF1/AMP kinase-related kinase as an NF-kappaB-regulated anti-apoptotic kinase involved in CD95-induced motility and invasiveness. |
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. |
Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family. |