Gene Symbol | Gcm2 |
Entrez Gene ID | 291047 |
Full Name | glial cells missing homolog 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Gcm2 cDNA ORF clone
gRNAs
Gene Symbol | Gcm2 |
Entrez Gene ID | 291047 |
Full Name | glial cells missing homolog 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106105.1 | NP_001099575.1 | chorion-specific transcription factor GCMb |
Xenopus tropicalis (tropical clawed frog) | gcm2 | XP_002932714.1 |
GCM2 | XP_001088392.1 | |
Rattus norvegicus (Norway rat) | Gcm2 | NP_001099575.1 |
Danio rerio (zebrafish) | gcm2 | NP_001005603.1 |
Homo sapiens (human) | GCM2 | NP_004743.1 |
Bos taurus (cattle) | GCM2 | XP_002697663.2 |
Mus musculus (house mouse) | Gcm2 | NP_032130.2 |
Gallus gallus (chicken) | GCM2 | NP_001008480.1 |
Pan troglodytes (chimpanzee) | GCM2 | XP_518235.2 |
Canis lupus familiaris (dog) | GCM2 | XP_545339.3 |
GCM2-Activating Mutations in Familial Isolated Hyperparathyroidism.
Guan B, Welch JM, Sapp JC, Ling H, Li Y, Johnston JJ, Kebebew E, Biesecker LG, Simonds WF, Marx SJ, Agarwal SK
American journal of human genetics99(5)1034-1044(2016 Nov)
Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2.
Grigorieva IV, Mirczuk S, Gaynor KU, Nesbit MA, Grigorieva EF, Wei Q, Ali A, Fairclough RJ, Stacey JM, Stechman MJ, Mihai R, Kurek D, Fraser WD, Hough T, Condie BG, Manley N, Grosveld F, Thakker RV
The Journal of clinical investigation120(6)2144-55(2010 Jun)
Identification and characterization of novel parathyroid-specific transcription factor Glial Cells Missing Homolog B (GCMB) mutations in eight families with autosomal recessive hypoparathyroidism.
Bowl MR, Mirczuk SM, Grigorieva IV, Piret SE, Cranston T, Southam L, Allgrove J, Bahl S, Brain C, Loughlin J, Mughal Z, Ryan F, Shaw N, Thakker YV, Tiosano D, Nesbit MA, Thakker RV
Human molecular genetics19(10)2028-38(2010 May)
Parathyroid hormone regulates fetal-placental mineral homeostasis.
Simmonds CS, Karsenty G, Karaplis AC, Kovacs CS
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research25(3)594-605(2010 Mar)
Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia.
Liu Z, Yu S, Manley NR
Developmental biology305(1)333-46(2007 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Gcm2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gcm2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa04458 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106105.1 | |
Accession Version | NM_001106105.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1515bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | chorion-specific transcription factor GCMb | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473977.1. On or before Oct 4, 2007 this sequence version replaced XM_225247.4, XM_001061843.1. |
1 | ATGCCAGCAG ACAGCATGCA GGACCCCGAT CCTGTGCTTT CCTACGGGAT GAAACTCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099575.1 |
CDS | 181..1695 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCCAGCAG ACAGCATGCA GGACCCCGAT CCTGTGCTTT CCTACGGGAT GAAACTCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
GCM2-Activating Mutations in Familial Isolated Hyperparathyroidism. |
Gata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2. |
Identification and characterization of novel parathyroid-specific transcription factor Glial Cells Missing Homolog B (GCMB) mutations in eight families with autosomal recessive hypoparathyroidism. |
Parathyroid hormone regulates fetal-placental mineral homeostasis. |
Gcm2 is required for the differentiation and survival of parathyroid precursor cells in the parathyroid/thymus primordia. |