Gene Symbol | Ppargc1b |
Entrez Gene ID | 291567 |
Full Name | PPARG coactivator 1 beta |
Synonyms | PGC1beta,Perc |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ppargc1b cDNA ORF clone
gRNAs
Gene Symbol | Ppargc1b |
Entrez Gene ID | 291567 |
Full Name | PPARG coactivator 1 beta |
Synonyms | PGC1beta,Perc |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_176075.2 | NP_788264.1 | peroxisome proliferator-activated receptor gamma coactivator 1-beta |
Canis lupus familiaris (dog) | PPARGC1B | XP_546308.3 |
Xenopus tropicalis (tropical clawed frog) | ppargc1b | XP_002936744.2 |
Bos taurus (cattle) | PPARGC1B | XP_003586376.1 |
Rattus norvegicus (Norway rat) | Ppargc1b | NP_788264.1 |
Pan troglodytes (chimpanzee) | PPARGC1B | XP_003310943.1 |
LOC711027 | XP_002804631.1 | |
Danio rerio (zebrafish) | ppargc1b | XP_003199944.2 |
Homo sapiens (human) | PPARGC1B | NP_573570.3 |
Mus musculus (house mouse) | Ppargc1b | NP_573512.1 |
Gallus gallus (chicken) | PPARGC1B | XP_414479.4 |
PPAR Gamma Coactivator 1 Beta (PGC-1?) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons.
Liu YC, Gao XX, Zhang ZG, Lin ZH, Zou QL
Cellular and molecular neurobiology37(5)879-887(2017 Jul)
Peroxisome proliferator-activated receptor ? coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells.
Cho Y, Hazen BC, Russell AP, Kralli A
The Journal of biological chemistry288(35)25207-18(2013 Aug)
Peroxisome proliferator-activated receptor ? coactivator 1? (PGC-1?) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.
Guo Y, Fan Y, Zhang J, Chang L, Lin JD, Chen YE
The Journal of biological chemistry288(7)4625-36(2013 Feb)
PGC-1? modulates the expression of genes involved in mitochondrial function and adipogenesis during preadipocyte differentiation.
Ji H, Lu RH, Chang ZG, Su SS, Yang GS
Reproduction in domestic animals = Zuchthygiene47(3)419-27(2012 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells
Title: Peroxisome proliferator-activated receptor ? coactivator 1? (PGC-1?) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.
These observations suggest that PGC-1beta modulates the expression of mitochondrial function and adipogenesis-related genes and affects white preadipocyte differentiation.
Title: PGC-1? modulates the expression of genes involved in mitochondrial function and adipogenesis during preadipocyte differentiation.
An increase in Pgc-1beta expression in vivo activates a coordinated subset of genes that increase mitochondrial substrate oxidation, defend against oxidative stress and improve lipid-induced insulin resistance in skeletal muscle.
Title: Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1? involves reductions in long-chain acyl-CoA levels and oxidative stress.
PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons
Title: PGC-1{alpha} and PGC-1{beta} regulate mitochondrial density in neurons.
These data support an important role for PGC-1beta in the pathogenesis of fructose-induced insulin resistance.
Title: The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance.
The following Ppargc1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppargc1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa03985 | |
Clone ID Related Accession (Same CDS sequence) | NM_176075.2 | |
Accession Version | NM_176075.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2973bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-01 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | peroxisome proliferator-activated receptor gamma coactivator 1-beta | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY188951.1. On Jun 3, 2003 this sequence version replaced NM_176075.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY188951.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGCAGGGGG AAGGGAAGGG TGGGGAGTCT GGAGAGGAAC AGTTATGTGC TGACTTGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_788264.1 |
CDS | 1..2973 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCAGGGGG AAGGGAAGGG TGGGGAGTCT GGAGAGGAAC AGTTATGTGC TGACTTGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
PPAR Gamma Coactivator 1 Beta (PGC-1?) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons. |
Peroxisome proliferator-activated receptor ? coactivator 1 (PGC-1)- and estrogen-related receptor (ERR)-induced regulator in muscle 1 (Perm1) is a tissue-specific regulator of oxidative capacity in skeletal muscle cells. |
Peroxisome proliferator-activated receptor ? coactivator 1? (PGC-1?) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells. |
PGC-1? modulates the expression of genes involved in mitochondrial function and adipogenesis during preadipocyte differentiation. |