Gene Symbol | Wwox |
Entrez Gene ID | 292041 |
Full Name | WW domain-containing oxidoreductase |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Wwox cDNA ORF clone
Gene Symbol | Wwox |
Entrez Gene ID | 292041 |
Full Name | WW domain-containing oxidoreductase |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106188.1 | NP_001099658.1 | WW domain-containing oxidoreductase |
XM_006255670.3 | XP_006255732.1 | WW domain-containing oxidoreductase isoform X3 |
XM_006255666.3 | XP_006255728.1 | WW domain-containing oxidoreductase isoform X1 |
XM_008772491.2 | XP_008770713.1 | WW domain-containing oxidoreductase isoform X2 |
XM_006255671.3 | XP_006255733.1 | WW domain-containing oxidoreductase isoform X4 |
Pan troglodytes (chimpanzee) | WWOX | XP_001144696.2 |
Canis lupus familiaris (dog) | WWOX | XP_852623.2 |
Caenorhabditis elegans (roundworm) | dhs-8 | NP_001022250.1 |
Caenorhabditis elegans (roundworm) | K10H10.6 | NP_497012.1 |
Danio rerio (zebrafish) | wwox | NP_957207.1 |
Drosophila melanogaster (fruit fly) | Wwox | NP_609171.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008423 | XP_317022.4 |
Caenorhabditis elegans (roundworm) | dhs-7 | NP_495500.1 |
Caenorhabditis elegans (roundworm) | E04F6.15 | NP_495501.1 |
Oryza sativa (rice) | Os04g0291100 | NP_001052391.1 |
Oryza sativa (rice) | Os04g0291000 | NP_001173846.1 |
Mus musculus (house mouse) | Wwox | NP_062519.2 |
Gallus gallus (chicken) | WWOX | NP_001025745.1 |
Caenorhabditis elegans (roundworm) | CELE_DC2.5 | NP_503155.4 |
Caenorhabditis elegans (roundworm) | F32A5.8 | NP_495516.2 |
Homo sapiens (human) | WWOX | NP_057457.1 |
WWOX | XP_001105944.2 | |
Bos taurus (cattle) | WWOX | NP_001071560.1 |
Rattus norvegicus (Norway rat) | Wwox | NP_001099658.1 |
The fragile site WWOX gene and the developing brain.
Tabarki B, Al Mutairi F, Al Hashem A
Experimental biology and medicine (Maywood, N.J.)240(3)400-2(2015 Mar)
Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats.
Li MY, Lai FJ, Hsu LJ, Lo CP, Cheng CL, Lin SR, Lee MH, Chang JY, Subhan D, Tsai MS, Sze CI, Pugazhenthi S, Chang NS, Chen ST
PloS one4(11)e7820(2009 Nov)
A spontaneous mutation of the Wwox gene and audiogenic seizures in rats with lethal dwarfism and epilepsy.
Suzuki H, Katayama K, Takenaka M, Amakasu K, Saito K, Suzuki K
Genes, brain, and behavior8(7)650-60(2009 Oct)
Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein.
Bouteille N, Driouch K, Hage PE, Sin S, Formstecher E, Camonis J, Lidereau R, Lallemand F
Oncogene28(28)2569-80(2009 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
WWOX plays a critical role in normal central nervous system development and disease.
Title: The fragile site WWOX gene and the developing brain.
WWOX/WOX1 is coactivated with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats
Title: Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats.
The Wwox protein is expressed in the central nervous system (CNS), indicating that abnormal neuronal excitability in lde/lde rats may be because of a lack of Wwox function.
Title: A spontaneous mutation of the Wwox gene and audiogenic seizures in rats with lethal dwarfism and epilepsy.
The following Wwox gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wwox cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa04507 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106188.1 | |
Accession Version | NM_001106188.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1071bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | WW domain-containing oxidoreductase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473972.1. On or before Oct 4, 2007 this sequence version replaced XM_214696.3, XM_001076479.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099658.1 |
CDS | 102..1172 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106188.1 |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa38959 | |
Clone ID Related Accession (Same CDS sequence) | XM_006255666.3 | |
Accession Version | XM_006255666.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1245bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | WW domain-containing oxidoreductase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255666.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006255728.1 |
CDS | 211..1455 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006255666.3 |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa38963 | |
Clone ID Related Accession (Same CDS sequence) | XM_006255670.3 | |
Accession Version | XM_006255670.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1077bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | WW domain-containing oxidoreductase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255670.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006255732.1 |
CDS | 205..1281 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006255670.3 |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa38964 | |
Clone ID Related Accession (Same CDS sequence) | XM_006255671.3 | |
Accession Version | XM_006255671.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1074bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | WW domain-containing oxidoreductase isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006255671.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006255733.1 |
CDS | 204..1277 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006255671.3 |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa45017 | |
Clone ID Related Accession (Same CDS sequence) | XM_008772491.2 | |
Accession Version | XM_008772491.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1191bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | WW domain-containing oxidoreductase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005118.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008772491.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008770713.1 |
CDS | 218..1408 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008772491.2 |
1 | ATGGCAGCTC TGCGCTATGC GGGCCTGGAT GACACGGACA GTGAGGATGA GCTGCCTCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The fragile site WWOX gene and the developing brain. |
Dramatic co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transection in rats. |
A spontaneous mutation of the Wwox gene and audiogenic seizures in rats with lethal dwarfism and epilepsy. |
Inhibition of the Wnt/beta-catenin pathway by the WWOX tumor suppressor protein. |