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Snrpa cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Snrpa
Entrez Gene ID 292729
Full Name small nuclear ribonucleoprotein polypeptide A
General protein information
Preferred Names

small nuclear ribonucleoprotein polypeptide A

Names

U1 small nuclear ribonucleoprotein A
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

1

1q21

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001008303.1 NP_001008304.1 U1 small nuclear ribonucleoprotein A
XM_006228564.3 XP_006228626.1 U1 small nuclear ribonucleoprotein A isoform X1

Pathways from BioSystems


Homologies


Canis lupus familiaris (dog) SNRPA XP_533663.2
Anopheles gambiae (African malaria mosquito) AgaP_AGAP011637 XP_320869.2
Oryza sativa (rice) Os05g0154800 NP_001054685.1
Bos taurus (cattle) SNRPA NP_001039504.1
Homo sapiens (human) SNRPA NP_004587.1
Rattus norvegicus (Norway rat) Snrpa NP_001008304.1
Danio rerio (zebrafish) snrpa NP_955965.1
Caenorhabditis elegans (roundworm) rnp-2 NP_500504.1
Schizosaccharomyces pombe (fission yeast) usp102 NP_596424.1
Pan troglodytes (chimpanzee) SNRPA XP_512674.2
SNRPA XP_001098504.1
Drosophila melanogaster (fruit fly) snf NP_511045.1
Neurospora crassa NCU08034 XP_962704.1
Magnaporthe oryzae (rice blast fungus) MGG_07085 XP_003715274.1
Arabidopsis thaliana (thale cress) U1A NP_182280.1
Xenopus tropicalis (tropical clawed frog) snrpa NP_001016784.1

Gene Ontology


Bibliography

Related articles in PubMed

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
Kondo Y, Oubridge C, van Roon AM, Nagai K
eLife4(2015 Jan)

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wingo TS, Sun YE, Jin P, Hanfelt J, Willcock DM, Levey A, Lah JJ, Peng J
Proceedings of the National Academy of Sciences of the United States of America110(41)16562-7(2013 Oct)

The nuclear cap-binding complex interacts with the U4/U6?U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.
Pabis M, Neufeld N, Steiner MC, Bojic T, Shav-Tal Y, Neugebauer KM
RNA (New York, N.Y.)19(8)1054-63(2013 Aug)

Structural analyses of the pre-mRNA splicing machinery.
Zhang L, Li X, Zhao R
Protein science : a publication of the Protein Society22(6)677-92(2013 Jun)

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Baltz AG, Munschauer M, Schwanh?usser B, Vasile A, Murakawa Y, Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E, Bonneau R, Selbach M, Dieterich C, Landthaler M
Molecular cell46(5)674-90(2012 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Snrpa gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Snrpa cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa11239 NM_001008303.1
Latest version!		 Rattus norvegicus small nuclear ribonucleoprotein polypeptide A (Snrpa), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
ORa11239 XM_006228564.3
Latest version!		 Rattus norvegicus small nuclear ribonucleoprotein polypeptide A (Snrpa), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa11239
Clone ID Related Accession (Same CDS sequence) NM_001008303.1 , XM_006228564.3
Accession Version NM_001008303.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 846bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-18
Organism Rattus norvegicus(Norway rat)
Product U1 small nuclear ribonucleoprotein A
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC086331.1. On Dec 16, 2004 this sequence version replaced XM_214845.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC086331.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCAGTTC CCGAGACCCG TCCCAACCAC ACTATTTATA TCAACAATCT CAATGAGAAG 
ATCAAGAAAG ATGAGCTCAA GAAGTCCCTG TATGCCATCT TCTCCCAGTT TGGCCAGATC 
CTGGATATCC TGGTGTCTCG GAGCCTGAAG ATGAGGGGCC AGGCCTTCGT CATCTTCAAG 
GAGGTCAGCA GTGCCACCAA CGCCCTGCGT TCCATGCAGG GCTTCCCTTT CTACGACAAG 
CCCATGCGTA TCCAGTACGC AAAGACTGAC TCAGACATCA TTGCCAAAAT GAAGGGCACC 
TTTGTGGAGA GAGATCGCAA ACGTGAGAAG AGGAAGCCCA AGAGTCAGGA GACACCTGCT 
GCCAAAAAGG CTGTTCAGGG TGGGGCAGCT GCCCCTGTGG TTGGCGCTGT CCAGCCTGTA 
CCGGGCATGC CACCGATGAC TCAGGCACCC CGCATCATGC ACCACATGCC AGGACAGCCT 
CCCTACATGC CACCACCTGG CATGATCCCG CCACCAGGCC TTGCTCCTGG CCAGATCCCT 
CCTGGGGCAA TGCCCCCACA GCAGCTCATG CCTGGGCAGA TGCCACCTGC CCAACCTCTC 
TCGGAGAATC CACCCAATCA CATCCTGTTC CTCACCAACC TGCCTGAGGA GACCAACGAG 
CTCATGCTCT CCATGCTCTT CAACCAGTTC CCTGGCTTCA AGGAGGTGCG TCTGGTCCCT 
GGGCGCCATG ACATTGCCTT CGTGGAGTTT GACAATGAAG TGCAGGCTGG GGCAGCACGA 
GATGCCCTGC AAGGCTTCAA GATCACACAG AACAATGCAA TGAAGATCTC TTTTGCCAAG 
AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001008304.1
CDS86..931
Translation

Target ORF information:

RefSeq Version NM_001008303.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus small nuclear ribonucleoprotein polypeptide A (Snrpa), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001008303.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCAGTTC CCGAGACCCG TCCCAACCAC ACTATTTATA TCAACAATCT CAATGAGAAG 
ATCAAGAAAG ATGAGCTCAA GAAGTCCCTG TATGCCATCT TCTCCCAGTT TGGCCAGATC 
CTGGATATCC TGGTGTCTCG GAGCCTGAAG ATGAGGGGCC AGGCCTTCGT CATCTTCAAG 
GAGGTCAGCA GTGCCACCAA CGCCCTGCGT TCCATGCAGG GCTTCCCTTT CTACGACAAG 
CCCATGCGTA TCCAGTACGC AAAGACTGAC TCAGACATCA TTGCCAAAAT GAAGGGCACC 
TTTGTGGAGA GAGATCGCAA ACGTGAGAAG AGGAAGCCCA AGAGTCAGGA GACACCTGCT 
GCCAAAAAGG CTGTTCAGGG TGGGGCAGCT GCCCCTGTGG TTGGCGCTGT CCAGCCTGTA 
CCGGGCATGC CACCGATGAC TCAGGCACCC CGCATCATGC ACCACATGCC AGGACAGCCT 
CCCTACATGC CACCACCTGG CATGATCCCG CCACCAGGCC TTGCTCCTGG CCAGATCCCT 
CCTGGGGCAA TGCCCCCACA GCAGCTCATG CCTGGGCAGA TGCCACCTGC CCAACCTCTC 
TCGGAGAATC CACCCAATCA CATCCTGTTC CTCACCAACC TGCCTGAGGA GACCAACGAG 
CTCATGCTCT CCATGCTCTT CAACCAGTTC CCTGGCTTCA AGGAGGTGCG TCTGGTCCCT 
GGGCGCCATG ACATTGCCTT CGTGGAGTTT GACAATGAAG TGCAGGCTGG GGCAGCACGA 
GATGCCCTGC AAGGCTTCAA GATCACACAG AACAATGCAA TGAAGATCTC TTTTGCCAAG 
AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa11239
Clone ID Related Accession (Same CDS sequence) NM_001008303.1 , XM_006228564.3
Accession Version XM_006228564.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 846bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product U1 small nuclear ribonucleoprotein A isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228564.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCAGTTC CCGAGACCCG TCCCAACCAC ACTATTTATA TCAACAATCT CAATGAGAAG 
ATCAAGAAAG ATGAGCTCAA GAAGTCCCTG TATGCCATCT TCTCCCAGTT TGGCCAGATC 
CTGGATATCC TGGTGTCTCG GAGCCTGAAG ATGAGGGGCC AGGCCTTCGT CATCTTCAAG 
GAGGTCAGCA GTGCCACCAA CGCCCTGCGT TCCATGCAGG GCTTCCCTTT CTACGACAAG 
CCCATGCGTA TCCAGTACGC AAAGACTGAC TCAGACATCA TTGCCAAAAT GAAGGGCACC 
TTTGTGGAGA GAGATCGCAA ACGTGAGAAG AGGAAGCCCA AGAGTCAGGA GACACCTGCT 
GCCAAAAAGG CTGTTCAGGG TGGGGCAGCT GCCCCTGTGG TTGGCGCTGT CCAGCCTGTA 
CCGGGCATGC CACCGATGAC TCAGGCACCC CGCATCATGC ACCACATGCC AGGACAGCCT 
CCCTACATGC CACCACCTGG CATGATCCCG CCACCAGGCC TTGCTCCTGG CCAGATCCCT 
CCTGGGGCAA TGCCCCCACA GCAGCTCATG CCTGGGCAGA TGCCACCTGC CCAACCTCTC 
TCGGAGAATC CACCCAATCA CATCCTGTTC CTCACCAACC TGCCTGAGGA GACCAACGAG 
CTCATGCTCT CCATGCTCTT CAACCAGTTC CCTGGCTTCA AGGAGGTGCG TCTGGTCCCT 
GGGCGCCATG ACATTGCCTT CGTGGAGTTT GACAATGAAG TGCAGGCTGG GGCAGCACGA 
GATGCCCTGC AAGGCTTCAA GATCACACAG AACAATGCAA TGAAGATCTC TTTTGCCAAG 
AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006228626.1
CDS219..1064
Translation

Target ORF information:

RefSeq Version XM_006228564.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus small nuclear ribonucleoprotein polypeptide A (Snrpa), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006228564.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
ATGGCAGTTC CCGAGACCCG TCCCAACCAC ACTATTTATA TCAACAATCT CAATGAGAAG 
ATCAAGAAAG ATGAGCTCAA GAAGTCCCTG TATGCCATCT TCTCCCAGTT TGGCCAGATC 
CTGGATATCC TGGTGTCTCG GAGCCTGAAG ATGAGGGGCC AGGCCTTCGT CATCTTCAAG 
GAGGTCAGCA GTGCCACCAA CGCCCTGCGT TCCATGCAGG GCTTCCCTTT CTACGACAAG 
CCCATGCGTA TCCAGTACGC AAAGACTGAC TCAGACATCA TTGCCAAAAT GAAGGGCACC 
TTTGTGGAGA GAGATCGCAA ACGTGAGAAG AGGAAGCCCA AGAGTCAGGA GACACCTGCT 
GCCAAAAAGG CTGTTCAGGG TGGGGCAGCT GCCCCTGTGG TTGGCGCTGT CCAGCCTGTA 
CCGGGCATGC CACCGATGAC TCAGGCACCC CGCATCATGC ACCACATGCC AGGACAGCCT 
CCCTACATGC CACCACCTGG CATGATCCCG CCACCAGGCC TTGCTCCTGG CCAGATCCCT 
CCTGGGGCAA TGCCCCCACA GCAGCTCATG CCTGGGCAGA TGCCACCTGC CCAACCTCTC 
TCGGAGAATC CACCCAATCA CATCCTGTTC CTCACCAACC TGCCTGAGGA GACCAACGAG 
CTCATGCTCT CCATGCTCTT CAACCAGTTC CCTGGCTTCA AGGAGGTGCG TCTGGTCCCT 
GGGCGCCATG ACATTGCCTT CGTGGAGTTT GACAATGAAG TGCAGGCTGG GGCAGCACGA 
GATGCCCTGC AAGGCTTCAA GATCACACAG AACAATGCAA TGAAGATCTC TTTTGCCAAG 
AAGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
eLife4(2015 Jan)
Kondo Y,Oubridge C,van Roon AM,Nagai K


book

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America110(41)16562-7(2013 Oct)
Bai B,Hales CM,Chen PC,Gozal Y,Dammer EB,Fritz JJ,Wang X,Xia Q,Duong DM,Street C,Cantero G,Cheng D,Jones DR,Wu Z,Li Y,Diner I,Heilman CJ,Rees HD,Wu H,Lin L,Szulwach KE,Gearing M,Mufson EJ,Bennett DA,Montine TJ,Seyfried NT,Wingo TS,Sun YE,Jin P,Hanfelt J,Willcock DM,Levey A,Lah JJ,Peng J


book

The nuclear cap-binding complex interacts with the U4/U6?U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.
RNA (New York, N.Y.)19(8)1054-63(2013 Aug)
Pabis M,Neufeld N,Steiner MC,Bojic T,Shav-Tal Y,Neugebauer KM


book

Structural analyses of the pre-mRNA splicing machinery.
Protein science : a publication of the Protein Society22(6)677-92(2013 Jun)
Zhang L,Li X,Zhao R


book

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
Molecular cell46(5)674-90(2012 Jun)
Baltz AG,Munschauer M,Schwanh?usser B,Vasile A,Murakawa Y,Schueler M,Youngs N,Penfold-Brown D,Drew K,Milek M,Wyler E,Bonneau R,Selbach M,Dieterich C,Landthaler M