Gene Symbol | Ftl1 |
Entrez Gene ID | 29292 |
Full Name | ferritin light chain 1 |
Synonyms | Ftl |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | iron-storage protein [RGD, Feb 2006]. |
ORF » Species Summary » Rattus norvegicus » Ftl1 cDNA ORF clone
Gene Symbol | Ftl1 |
Entrez Gene ID | 29292 |
Full Name | ferritin light chain 1 |
Synonyms | Ftl |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | iron-storage protein [RGD, Feb 2006]. |
mRNA | Protein | Name |
---|---|---|
NM_022500.4 | NP_071945.3 | ferritin light chain 1 |
Pan troglodytes (chimpanzee) | FTL | XP_001155938.2 |
FTL | XP_002801381.1 | |
Canis lupus familiaris (dog) | LOC102155200 | XP_005634393.1 |
Bos taurus (cattle) | LOC788801 | XP_003587783.2 |
Rattus norvegicus (Norway rat) | RGD1566189 | XP_574537.1 |
Rattus norvegicus (Norway rat) | LOC100360087 | XP_002729599.1 |
Rattus norvegicus (Norway rat) | LOC100363177 | XP_002729061.1 |
Xenopus tropicalis (tropical clawed frog) | MGC75752 | NP_989212.1 |
Canis lupus familiaris (dog) | FTL | NP_001019807.1 |
Rattus norvegicus (Norway rat) | Ftl1l1 | XP_577041.1 |
LOC100427851 | XP_002802741.1 | |
Bos taurus (cattle) | LOC783224 | XP_002685102.3 |
Rattus norvegicus (Norway rat) | Ftl1 | NP_071945.3 |
Bos taurus (cattle) | FTL | NP_777217.1 |
Mus musculus (house mouse) | Gm20746 | XP_003688927.2 |
Rattus norvegicus (Norway rat) | LOC100359668 | XP_002729671.1 |
Homo sapiens (human) | FTL | NP_000137.2 |
LOC718777 | XP_002799272.1 | |
Bos taurus (cattle) | LOC101904953 | XP_005208358.1 |
Mus musculus (house mouse) | Ftl1 | NP_034370.2 |
Rattus norvegicus (Norway rat) | LOC100362384 | XP_002728087.1 |
Rattus norvegicus (Norway rat) | RGD1560687 | XP_576192.1 |
Widespread macromolecular interaction perturbations in human genetic disorders.
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kov?cs IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barab?si AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M
Cell161(3)647-660(2015 Apr)
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Dowdle WE, Nyfeler B, Nagel J, Elling RA, Liu S, Triantafellow E, Menon S, Wang Z, Honda A, Pardee G, Cantwell J, Luu C, Cornella-Taracido I, Harrington E, Fekkes P, Lei H, Fang Q, Digan ME, Burdick D, Powers AF, Helliwell SB, D'Aquin S, Bastien J, Wang H, Wiederschain D, Kuerth J, Bergman P, Schwalb D, Thomas J, Ugwonali S, Harbinski F, Tallarico J, Wilson CJ, Myer VE, Porter JA, Bussiere DE, Finan PM, Labow MA, Mao X, Hamann LG, Manning BD, Valdez RA, Nicholson T, Schirle M, Knapp MS, Keaney EP, Murphy LO
Nature cell biology16(11)1069-79(2014 Nov)
Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration.
Finazzi D, Arosio P
Archives of toxicology88(10)1787-802(2014 Oct)
Differential regulation of ferritin subunits and iron transport proteins: an effect of targeted hepatic X-irradiation.
Naz N, Ahmad S, Cameron S, Moriconi F, Rave-Fr?nk M, Christiansen H, Hess CF, Ramadori G, Malik IA
BioMed research international2013353106(2013)
A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation.
Adams LD, Lemire JM, Schwartz SM
Arteriosclerosis, thrombosis, and vascular biology19(11)2600-8(1999 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
FTL can be used as a serum marker for early phase radiation-induced liver damage.
Title: Differential regulation of ferritin subunits and iron transport proteins: an effect of targeted hepatic X-irradiation.
Data suggest that soluble transferrin receptor (sTfR) indices and the ratio of sTfR/ferritin could be useful indicators for monitoring iron deficiency during endurance training.
Title: The ratio of sTfR/ferritin is associated with the expression level of TfR in rat bone marrow cells after endurance exercise.
Up-regulation of the expression of Ft-L could represent a protective response to the increased oxidative stress in the aging myocardium.
Title: Iron, ferritin and proteins of the methionine-centered redox cycle in young and old rat hearts.
Ftl expression in rat hepatocytes and Kupffer cells after lead nitrate treatment is reported.
Title: Ferritin expression in rat hepatocytes and Kupffer cells after lead nitrate treatment.
The following Ftl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ftl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa05775 | |
Clone ID Related Accession (Same CDS sequence) | NM_022500.4 | |
Accession Version | NM_022500.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 552bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ferritin light chain 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC061525.1. On Aug 31, 2012 this sequence version replaced NM_022500.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC061525.1, FQ211261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906347, SAMN01906349 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACCTCTC AGATTCGTCA GAATTATTCC ACCGAAGTGG AAGCTGCCGT GAACCGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_071945.3 |
CDS | 206..757 |
Translation |
Target ORF information:
Target ORF information:
|
NM_022500.4 |
1 | ATGACCTCTC AGATTCGTCA GAATTATTCC ACCGAAGTGG AAGCTGCCGT GAACCGCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Widespread macromolecular interaction perturbations in human genetic disorders. |
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. |
Biology of ferritin in mammals: an update on iron storage, oxidative damage and neurodegeneration. |
Differential regulation of ferritin subunits and iron transport proteins: an effect of targeted hepatic X-irradiation. |
A systematic analysis of 40 random genes in cultured vascular smooth muscle subtypes reveals a heterogeneity of gene expression and identifies the tight junction gene zonula occludens 2 as a marker of epithelioid "pup" smooth muscle cells and a participant in carotid neointimal formation. |