Gene Symbol | C2cd3 |
Entrez Gene ID | 293148 |
Full Name | C2 calcium-dependent domain containing 3 |
Synonyms | RGD1307366 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » C2cd3 cDNA ORF clone
Gene Symbol | C2cd3 |
Entrez Gene ID | 293148 |
Full Name | C2 calcium-dependent domain containing 3 |
Synonyms | RGD1307366 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017588950.1 | XP_017444439.1 | C2 domain-containing protein 3 isoform X1 |
XM_017588951.1 | XP_017444440.1 | C2 domain-containing protein 3 isoform X2 |
XM_017588953.1 | XP_017444442.1 | C2 domain-containing protein 3 isoform X4 |
NM_001191602.1 | NP_001178531.1 | C2 domain-containing protein 3 |
XM_017588952.1 | XP_017444441.1 | C2 domain-containing protein 3 isoform X3 |
C2CD3 | XP_001115612.2 | |
Gallus gallus (chicken) | C2CD3 | XP_417250.4 |
Danio rerio (zebrafish) | si:ch211-149e23.1 | XP_001337534.5 |
Homo sapiens (human) | C2CD3 | NP_001273506.1 |
Canis lupus familiaris (dog) | C2CD3 | XP_005633840.1 |
Pan troglodytes (chimpanzee) | C2CD3 | XP_003952022.1 |
Xenopus tropicalis (tropical clawed frog) | c2cd3 | NP_001072727.1 |
Mus musculus (house mouse) | C2cd3 | NP_001017985.2 |
Rattus norvegicus (Norway rat) | C2cd3 | NP_001178531.1 |
The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation.
Thauvin-Robinet C, Lee JS, Lopez E, Herranz-P?rez V, Shida T, Franco B, Jego L, Ye F, Pasquier L, Loget P, Gigot N, Aral B, Lopes CA, St-Onge J, Bruel AL, Thevenon J, Gonz?lez-Granero S, Alby C, Munnich A, Vekemans M, Huet F, Fry AM, Saunier S, Rivi?re JB, Atti?-Bitach T, Garcia-Verdugo JM, Faivre L, M?garban? A, Nachury MV
Nature genetics46(8)905-11(2014 Aug)
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
Ye X, Zeng H, Ning G, Reiter JF, Liu A
Proceedings of the National Academy of Sciences of the United States of America111(6)2164-9(2014 Feb)
Discovering regulators of centriole biogenesis through siRNA-based functional genomics in human cells.
Balestra FR, Strnad P, Fl?ckiger I, G?nczy P
Developmental cell25(6)555-71(2013 Jun)
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS
The EMBO journal30(8)1520-35(2011 Apr)
C2cd3 is required for cilia formation and Hedgehog signaling in mouse.
Hoover AN, Wynkoop A, Zeng H, Jia J, Niswander LA, Liu A
Development (Cambridge, England)135(24)4049-58(2008 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following C2cd3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C2cd3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa56480 | |
Clone ID Related Accession (Same CDS sequence) | XM_017588953.1 | |
Accession Version | XM_017588953.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5829bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | C2 domain-containing protein 3 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444442.1 |
CDS | 106..5934 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017588953.1 |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa56477 | |
Clone ID Related Accession (Same CDS sequence) | XM_017588950.1 | |
Accession Version | XM_017588950.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6975bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | C2 domain-containing protein 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444439.1 |
CDS | 106..7080 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017588950.1 |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa56478 | |
Clone ID Related Accession (Same CDS sequence) | XM_017588951.1 | |
Accession Version | XM_017588951.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6900bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | C2 domain-containing protein 3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444440.1 |
CDS | 106..7005 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017588951.1 |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa56479 | |
Clone ID Related Accession (Same CDS sequence) | XM_017588952.1 | |
Accession Version | XM_017588952.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6771bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | C2 domain-containing protein 3 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017444441.1 |
CDS | 106..6876 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017588952.1 |
1 | ATGAAGTCCT CAAATAGTGT ATCAATTTGC GCTTGCGCAG CTGCAGGTGT CCTGGTCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa07114 | |
Clone ID Related Accession (Same CDS sequence) | NM_001191602.1 | |
Accession Version | NM_001191602.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6960bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-09 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | C2 domain-containing protein 3 | |
Comment | Comment: INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from AC134944.3. On Jul 17, 2010 this sequence version replaced XM_215006.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAACAAC GGAAAGGCCA AGTGCCTGGG GGCGGCCGTG GGCGCAAGAA GCGAGGTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001178531.1 |
CDS | 1..6960 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001191602.1 |
1 | ATGAAACAAC GGAAAGGCCA AGTGCCTGGG GGCGGCCGTG GGCGCAAGAA GCGAGGTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation. |
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals. |
Discovering regulators of centriole biogenesis through siRNA-based functional genomics in human cells. |
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. |
C2cd3 is required for cilia formation and Hedgehog signaling in mouse. |