Lyve1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Lyve1
Entrez Gene ID	293186
Full Name	lymphatic vessel endothelial hyaluronan receptor 1
Synonyms	Xlkd1
General protein information	Preferred Names lymphatic vessel endothelial hyaluronan receptor 1 Names lymphatic vessel endothelial hyaluronic acid receptor 1 extra cellular link domain-containing 1 extracellular link domain-containing 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q33

mRNA and Protein(s)

mRNA Protein Name

NM_001106286.1 NP_001099756.1 lymphatic vessel endothelial hyaluronic acid receptor 1
Pathways from BioSystems

mRNA	Protein	Name
NM_001106286.1	NP_001099756.1	lymphatic vessel endothelial hyaluronic acid receptor 1

Homologies

Pan troglodytes (chimpanzee)	LYVE1	XP_508283.2
Mus musculus (house mouse)	Lyve1	NP_444477.2
Bos taurus (cattle)	LYVE1	NP_991384.2
Homo sapiens (human)	LYVE1	NP_006682.2
Canis lupus familiaris (dog)	LYVE1	XP_003639831.1
Rattus norvegicus (Norway rat)	Lyve1	NP_001099756.1
Danio rerio (zebrafish)	LOC560618	XP_689109.3
Gallus gallus (chicken)	LYVE1	NP_001186516.1
	LYVE1	XP_001100103.1
Xenopus tropicalis (tropical clawed frog)	lyve1	XP_002942315.2

Gene Ontology
Bibliography

Related articles in PubMed

Temporal expression of hyaluronic acid and hyaluronic acid receptors in a porcine small intestinal submucosa-augmented rat bladder regeneration model.
Mondalek FG, Fung KM, Yang Q, Wu W, Lu W, Palmer BW, Frimberger DC, Greenwood-Van Meerveld B, Hurst RE, Kropp BP, Lin HK
World journal of urology33(8)1119-28(2015 Aug)

Upregulation of hyaluronan and its binding receptors in an experimental model of chronic cyclosporine nephropathy.
Han DH, Song HK, Lee SY, Song JH, Piao SG, Yoon HE, Ghee JY, Yoon HJ, Kim J, Yang CW
Nephrology (Carlton, Vic.)15(2)216-24(2010 Mar)

Characterization of the dental lymphatic system and identification of cells immunopositive to specific lymphatic markers.
Berggreen E, Haug SR, Mkonyi LE, Bletsa A
European journal of oral sciences117(1)34-42(2009 Feb)

Distribution of LYVE-1 and CD31 in postnatal rat masseter muscle.
Sato I, Imura K, Miwa Y, Miyado M, Sunohara M
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft190(4)329-38(2008)

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain.
Takayanagi S, Hiroyama T, Yamazaki S, Nakajima T, Morita Y, Usui J, Eto K, Motohashi T, Shiomi K, Keino-Masu K, Masu M, Oike Y, Mori S, Yoshida N, Iwama A, Nakauchi H
Blood107(11)4317-25(2006 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of Lyve1 followed the same temporal pattern as hyaluronic acid deposition in a bladder regeneration model.
Title: Temporal expression of hyaluronic acid and hyaluronic acid receptors in a porcine small intestinal submucosa-augmented rat bladder regeneration model.

Upregulation of hyaluronan and its binding receptors CD44 and LYVE-1 are involved in interstitial fibrosis in chronic cyclosporine-induced renal injury.
Title: Upregulation of hyaluronan and its binding receptors in an experimental model of chronic cyclosporine nephropathy.

Immunostaining for the specific lymphatic markers LYVE-1 revealed an extensive lymphatic vessel system in dental tissues. Unexpected cell staining for the above lymphatic markers was found in the pulp of both molars and incisors in rats.
Title: Characterization of the dental lymphatic system and identification of cells immunopositive to specific lymphatic markers.

Different levels of protein for LYVE-1-positive cells may reflect alterations in the functional properties of the blood supply.
Title: Distribution of LYVE-1 and CD31 in postnatal rat masseter muscle.

The following Lyve1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lyve1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa00707	NM_001106286.1 Latest version!	Rattus norvegicus lymphatic vessel endothelial hyaluronan receptor 1 (Lyve1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$188.30 $269.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lyve1 ( NM_001106286.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099756.1 Rattus norvegicus lymphatic vessel endothelial hyaluronan receptor 1 (Lyve1), mRNA.

Price & Availability↑

CloneID	ORa00707
Clone ID Related Accession (Same CDS sequence)	NM_001106286.1
Accession Version	NM_001106286.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1032bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-27
Organism	Rattus norvegicus(Norway rat)
Product	lymphatic vessel endothelial hyaluronic acid receptor 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473956.2. On or before Oct 4, 2007 this sequence version replaced XM_219001.4, XM_001077796.1. ##Evidence-Data-START## Transcript exon combination :: FQ103616.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906355 [ECO:0000348] ##Evidence-Data-END##

ATGCGCAACG TATTTCCAGA GCTCTCCATC CTGCGTGGTG ACTGCATTGT CTCCCTGGCC 
GCTGCAGTGC TCTGGGGGGT CTGCGCGATG CTCCAGCACT GCAGCCTGGT GTTACTCCTC 
GCCTCTCTTT GGACCACGAG GCACCCAGTC CATGGCACCG TCCAAGTGCA AGACCTTTCC 
ATTTCTCCAT GCAGAATCAT GGGCGTCGCC CTCGTGGGCA GAAATGCAGA CCCACAGATG 
AACTTCACAG AAGCCAAGGA GGTCTGTAAG GTTCTGGGAC TGACTCTGGC CAGCAGGAAC 
CAGGTGGAAT CCGCGCAGAA GTCTGGCTTC GAGACTTGCA GCTATGGATG GGTTGGAGAA 
CGGTTCTCAG TCATCCCTCG GATCTCCCCA AATCCCAAGT GTGGGAAGAA TGGCAAAGGT 
GTCCTGATTT GGAACGCTTC CCCCAGCCAA AAGTTCAGAG TCTATTGCCA CAACTCATCT 
GACACCTGGG CCAACTCCTG CTTTCCAGAA ATCACTACCA CATTCAACAC TCAAACCCCT 
GCAGCAGAGT TTTCTGTCAG CAGCGACACC TACTCGGCTT CATCCTCAGA CTCCACAACG 
TCTGCGTCTG CCACCACCCG GGCTCCACCT TTGACCACCA TGGCACGGAA GACAAAAATG 
ATTTGTATCA CGGAAGTTTA CACAGAACCT ATCACCATGG ATGCAGAAAC AGAAGCATCT 
GTTGAAAGTG GAGCAGCATT CAAGAATGAA GCAGCTGGGT TTGGAGGTGT CCCCACAACC 
CTGCTGGTGC TGGCTCTCTT CTTCTTTGGT GCTGCAGCTG TGCTGGGTGT TTGCTACGTG 
AAAAGGTATG TGAAGGCCTT CCCTTTCACA AACAAGAATC AACAGAAGGA AATGATCGAA 
ACCAAGGTTG TAAAGGAAGA GAAAGCTGAT GATGTCAATG CTAATGAAGA ATCAAAGAAA 
ATGGTTAAAA ACTCAGAGGA GCCCAAGAGT CCACCCAAAA CTACAGTGCG GTGCCTAGAG 
GCTGAAGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099756.1
CDS	273..1304
Translation	MRNVFPELSILRGDCIVSLAAAVLWGVCAMLQHCSLVLLLASLWTTRHPVHGTVQVQDLSISPCRIMGVALVGRNADPQMNFTEAKEVCKVLGLTLASRNQVESAQKSGFETCSYGWVGERFSVIPRISPNPKCGKNGKGVLIWNASPSQKFRVYCHNSSDTWANSCFPEITTTFNTQTPAAEFSVSSDTYSASSSDSTTSASATTRAPPLTTMARKTKMICITEVYTEPITMDAETEASVESGAAFKNEAAGFGGVPTTLLVLALFFFGAAAVLGVCYVKRYVKAFPFTNKNQQKEMIETKVVKEEKADDVNANEESKKMVKNSEEPKSPPKTTVRCLEAEV

Target ORF information:

RefSeq Version	NM_001106286.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus lymphatic vessel endothelial hyaluronan receptor 1 (Lyve1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106286.1

ORF Insert Sequence:

ATGCGCAACG TATTTCCAGA GCTCTCCATC CTGCGTGGTG ACTGCATTGT CTCCCTGGCC 
GCTGCAGTGC TCTGGGGGGT CTGCGCGATG CTCCAGCACT GCAGCCTGGT GTTACTCCTC 
GCCTCTCTTT GGACCACGAG GCACCCAGTC CATGGCACCG TCCAAGTGCA AGACCTTTCC 
ATTTCTCCAT GCAGAATCAT GGGCGTCGCC CTCGTGGGCA GAAATGCAGA CCCACAGATG 
AACTTCACAG AAGCCAAGGA GGTCTGTAAG GTTCTGGGAC TGACTCTGGC CAGCAGGAAC 
CAGGTGGAAT CCGCGCAGAA GTCTGGCTTC GAGACTTGCA GCTATGGATG GGTTGGAGAA 
CGGTTCTCAG TCATCCCTCG GATCTCCCCA AATCCCAAGT GTGGGAAGAA TGGCAAAGGT 
GTCCTGATTT GGAACGCTTC CCCCAGCCAA AAGTTCAGAG TCTATTGCCA CAACTCATCT 
GACACCTGGG CCAACTCCTG CTTTCCAGAA ATCACTACCA CATTCAACAC TCAAACCCCT 
GCAGCAGAGT TTTCTGTCAG CAGCGACACC TACTCGGCTT CATCCTCAGA CTCCACAACG 
TCTGCGTCTG CCACCACCCG GGCTCCACCT TTGACCACCA TGGCACGGAA GACAAAAATG 
ATTTGTATCA CGGAAGTTTA CACAGAACCT ATCACCATGG ATGCAGAAAC AGAAGCATCT 
GTTGAAAGTG GAGCAGCATT CAAGAATGAA GCAGCTGGGT TTGGAGGTGT CCCCACAACC 
CTGCTGGTGC TGGCTCTCTT CTTCTTTGGT GCTGCAGCTG TGCTGGGTGT TTGCTACGTG 
AAAAGGTATG TGAAGGCCTT CCCTTTCACA AACAAGAATC AACAGAAGGA AATGATCGAA 
ACCAAGGTTG TAAAGGAAGA GAAAGCTGAT GATGTCAATG CTAATGAAGA ATCAAAGAAA 
ATGGTTAAAA ACTCAGAGGA GCCCAAGAGT CCACCCAAAA CTACAGTGCG GTGCCTAGAG 
GCTGAAGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Temporal expression of hyaluronic acid and hyaluronic acid receptors in a porcine small intestinal submucosa-augmented rat bladder regeneration model.
World journal of urology33(8)1119-28(2015 Aug)
Mondalek FG,Fung KM,Yang Q,Wu W,Lu W,Palmer BW,Frimberger DC,Greenwood-Van Meerveld B,Hurst RE,Kropp BP,Lin HK

Upregulation of hyaluronan and its binding receptors in an experimental model of chronic cyclosporine nephropathy.
Nephrology (Carlton, Vic.)15(2)216-24(2010 Mar)
Han DH,Song HK,Lee SY,Song JH,Piao SG,Yoon HE,Ghee JY,Yoon HJ,Kim J,Yang CW

Characterization of the dental lymphatic system and identification of cells immunopositive to specific lymphatic markers.
European journal of oral sciences117(1)34-42(2009 Feb)
Berggreen E,Haug SR,Mkonyi LE,Bletsa A

Distribution of LYVE-1 and CD31 in postnatal rat masseter muscle.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft190(4)329-38(2008)
Sato I,Imura K,Miwa Y,Miyado M,Sunohara M

Genetic marking of hematopoietic stem and endothelial cells: identification of the Tmtsp gene encoding a novel cell surface protein with the thrombospondin-1 domain.
Blood107(11)4317-25(2006 Jun)
Takayanagi S,Hiroyama T,Yamazaki S,Nakajima T,Morita Y,Usui J,Eto K,Motohashi T,Shiomi K,Keino-Masu K,Masu M,Oike Y,Mori S,Yoshida N,Iwama A,Nakauchi H

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Lyve1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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