Gene Symbol | Hoga1 |
Entrez Gene ID | 293949 |
Full Name | 4-hydroxy-2-oxoglutarate aldolase 1 |
Synonyms | Dhdpsl,Npl2,RGD1310475 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Hoga1 cDNA ORF clone
Gene Symbol | Hoga1 |
Entrez Gene ID | 293949 |
Full Name | 4-hydroxy-2-oxoglutarate aldolase 1 |
Synonyms | Dhdpsl,Npl2,RGD1310475 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106355.1 | NP_001099825.1 | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial |
XM_006231386.3 | XP_006231448.1 | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 |
Homo sapiens (human) | HOGA1 | NP_612422.2 |
Bos taurus (cattle) | HOGA1 | NP_001068705.1 |
Gallus gallus (chicken) | C10ORF65 | XP_001233352.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_07462 | XP_003711366.1 |
Neurospora crassa | NCU09532 | XP_957838.1 |
Pan troglodytes (chimpanzee) | HOGA1 | XP_001164461.1 |
Mus musculus (house mouse) | Hoga1 | NP_080428.1 |
Danio rerio (zebrafish) | hoga1 | NP_998035.1 |
Rattus norvegicus (Norway rat) | Hoga1 | NP_001099825.1 |
Canis lupus familiaris (dog) | HOGA1 | XP_850958.1 |
Xenopus tropicalis (tropical clawed frog) | hoga1 | NP_001263607.1 |
Primary hyperoxaluria type III gene HOGA1 (formerly DHDPSL) as a possible risk factor for idiopathic calcium oxalate urolithiasis.
Monico CG, Rossetti S, Belostotsky R, Cogal AG, Herges RM, Seide BM, Olson JB, Bergstrahl EJ, Williams HJ, Haley WE, Frishberg Y, Milliner DS
Clinical journal of the American Society of Nephrology : CJASN6(9)2289-95(2011 Sep)
Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria.
Riedel TJ, Johnson LC, Knight J, Hantgan RR, Holmes RP, Lowther WT
PloS one6(10)e26021(2011)
Mutations in DHDPSL are responsible for primary hyperoxaluria type III.
Belostotsky R, Seboun E, Idelson GH, Milliner DS, Becker-Cohen R, Rinat C, Monico CG, Feinstein S, Ben-Shalom E, Magen D, Weissman I, Charon C, Frishberg Y
American journal of human genetics87(3)392-9(2010 Sep)
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)
PURIFICATION AND PROPERTIES OF RAT LIVER 2-KETO-4-HYDROXYGLUTARATE ALDOLASE.
MAITRA U, DEKKER EE
The Journal of biological chemistry2391485-91(1964 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Hoga1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hoga1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01080 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106355.1 | |
Accession Version | NM_001106355.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473986.1. On or before Oct 4, 2007 this sequence version replaced XM_001058220.1, XM_215248.4. ##Evidence-Data-START## Transcript exon combination :: FQ210513.1, FQ218423.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGCTGGGCC CCCAAATCTG GGCCTCCATG AGGCAGGGGC TGAGCAGGGG CTTGTCTAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099825.1 |
CDS | 221..1186 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106355.1 |
1 | ATGCTGGGCC CCCAAATCTG GGCCTCCATG AGGCAGGGGC TGAGCAGGGG CTTGTCTAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa24085 | |
Clone ID Related Accession (Same CDS sequence) | XM_006231386.3 | |
Accession Version | XM_006231386.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 837bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006231386.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGGGCC CCCAAATCTG GGCCTCCATG AGGCAGGGGC TGAGCAGGGG CTTGTCTAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006231448.1 |
CDS | 349..1185 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006231386.3 |
1 | ATGCTGGGCC CCCAAATCTG GGCCTCCATG AGGCAGGGGC TGAGCAGGGG CTTGTCTAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Primary hyperoxaluria type III gene HOGA1 (formerly DHDPSL) as a possible risk factor for idiopathic calcium oxalate urolithiasis. |
Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. |
Mutations in DHDPSL are responsible for primary hyperoxaluria type III. |
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |
PURIFICATION AND PROPERTIES OF RAT LIVER 2-KETO-4-HYDROXYGLUTARATE ALDOLASE. |