Men1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Men1
Entrez Gene ID	29417
Full Name	menin 1
Synonyms	menin
General protein information	Preferred Names menin 1 Names menin multiple endocrine neoplasia 1 multiple endocrine neoplasia I multiple endocrine neoplasia type I
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 1 Map Location: 1q43
Summary	displays conservation with the human and mouse homologs for amino acid residues that are mutated in human multiple endocrine neoplasia type 1 [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_019208.3	NP_062081.1	menin
XM_006230772.3	XP_006230834.1	menin isoform X2
XM_006230770.3	XP_006230832.1	menin isoform X2
XM_006230771.3	XP_006230833.1	menin isoform X2
XM_006230769.3	XP_006230831.1	menin isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Men1	NP_032609.1
Homo sapiens (human)	MEN1	NP_000235.2
Canis lupus familiaris (dog)	MEN1	NP_001074977.1
	LOC722041	XP_001118239.2
Danio rerio (zebrafish)	men1	XP_003198971.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008130	XP_317329.4
Pan troglodytes (chimpanzee)	MEN1	XP_001167101.2
Bos taurus (cattle)	MEN1	NP_001069629.1
Xenopus tropicalis (tropical clawed frog)	men1	NP_001016361.1
Rattus norvegicus (Norway rat)	Men1	NP_062081.1
Drosophila melanogaster (fruit fly)	Mnn1	NP_001036342.1

Gene Ontology
Bibliography

Related articles in PubMed

MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.
Gillam MP, Nimbalkar D, Sun L, Christov K, Ray D, Kaldis P, Liu X, Kiyokawa H
Oncogene34(7)932-8(2015 Feb)

Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.
Ouyang M, Su W, Xiao L, Rao JN, Jiang L, Li Y, Turner DJ, Gorospe M, Wang JY
The Biochemical journal465(2)315-23(2015 Jan)

miR-24 regulates menin in the endocrine pancreas.
Vijayaraghavan J, Maggi EC, Crabtree JS
American journal of physiology. Endocrinology and metabolism307(1)E84-92(2014 Jul)

Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.
Hamze Z, Vercherat C, Bernigaud-Lacheretz A, Bazzi W, Bonnavion R, Lu J, Calender A, Pouponnot C, Bertolino P, Roche C, Stein R, Scoazec JY, Zhang CX, Cordier-Bussat M
Endocrine-related cancer20(6)833-48(2013 Dec)

HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene.
Borowiak M, Kuhlmann AS, Girard S, Gazzolo L, Mesnard JM, Jalinot P, Dodon MD
Carcinogenesis34(11)2664-72(2013 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CDK4 is a critical downstream target of MEN1-dependent tumor suppression and is required for tumorigenic proliferation in the pituitary and pancreatic islet, whereas CDK2 is dispensable for tumorigenesis in these neuroendocrine cell types.
Title: MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.

These findings indicate that miR-29b represses translation of Men1 mRNA, in turn affecting intestinal epithelial homoeostasis by altering IEC apoptosis.
Title: Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.

This study suggests that menin might serve as an important intracellular target of glucose to mediate the mitogenic effect that glucose exerts in pancreatic beta-cells.
Title: Glucose-mediated repression of menin promotes pancreatic ?-cell proliferation.

These results indicate that peripheral nerve injury induces upregulation of beta-catenins and menins in the dorsal horn of the spinal cord, which may contribute to the development of chronic neuropathic pain.
Title: Early changes of beta-Catenins and Menins in spinal cord dorsal horn after peripheral nerve injury.

data support a correlation between cyclin D1 expression, NF-kappaB activity and menin expression in this epithelial cell line and are relevant to the physiological function of menin in regulating proliferation in the intestinal epithelium.
Title: Relation between menin expression and NF-kappaB activity in an intestinal cell line.

The following Men1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Men1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa04034	NM_019208.3 Latest version!	Rattus norvegicus menin 1 (Men1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa04034	XM_006230771.3 Latest version!	Rattus norvegicus menin 1 (Men1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa04034	XM_006230770.3 Latest version!	Rattus norvegicus menin 1 (Men1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa04034	XM_006230772.3 Latest version!	Rattus norvegicus menin 1 (Men1), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$307.30 $439.00
ORa23751	XM_006230769.3 Latest version!	Rattus norvegicus menin 1 (Men1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Men1 ( NM_019208.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_062081.1 Rattus norvegicus menin 1 (Men1), mRNA.

Price & Availability↑

CloneID	ORa04034
Clone ID Related Accession (Same CDS sequence)	NM_019208.3 , XM_006230772.3 , XM_006230770.3 , XM_006230771.3
Accession Version	NM_019208.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-14
Organism	Rattus norvegicus(Norway rat)
Product	menin
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB773186.1, CB814296.1, AF130370.1, CV079282.1 and BQ193347.1. On Apr 13, 2007 this sequence version replaced NM_019208.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB023400.1, AF130369.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_062081.1
CDS	403..2235
Translation	MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREAEAAEAEEPWGDEAREGRRRGPRRESKPEEPPPPKKPALDKGPGSGQSAGSGPPRKTSGTVSGTARGTEVSSAAQAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL

Target ORF information:

RefSeq Version	NM_019208.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus menin 1 (Men1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_019208.3

ORF Insert Sequence:

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Men1 ( XM_006230772.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230834.1 Rattus norvegicus menin 1 (Men1), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa04034
Clone ID Related Accession (Same CDS sequence)	NM_019208.3 , XM_006230772.3 , XM_006230770.3 , XM_006230771.3
Accession Version	XM_006230772.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	menin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230772.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230834.1
CDS	205..2037
Translation	MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREAEAAEAEEPWGDEAREGRRRGPRRESKPEEPPPPKKPALDKGPGSGQSAGSGPPRKTSGTVSGTARGTEVSSAAQAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL

Target ORF information:

RefSeq Version	XM_006230772.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus menin 1 (Men1), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230772.3

ORF Insert Sequence:

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Men1 ( XM_006230770.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230832.1 Rattus norvegicus menin 1 (Men1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa04034
Clone ID Related Accession (Same CDS sequence)	NM_019208.3 , XM_006230772.3 , XM_006230770.3 , XM_006230771.3
Accession Version	XM_006230770.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	menin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230770.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230832.1
CDS	143..1975
Translation	MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREAEAAEAEEPWGDEAREGRRRGPRRESKPEEPPPPKKPALDKGPGSGQSAGSGPPRKTSGTVSGTARGTEVSSAAQAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL

Target ORF information:

RefSeq Version	XM_006230770.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus menin 1 (Men1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230770.3

ORF Insert Sequence:

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Men1 ( XM_006230771.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230833.1 Rattus norvegicus menin 1 (Men1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa04034
Clone ID Related Accession (Same CDS sequence)	NM_019208.3 , XM_006230772.3 , XM_006230770.3 , XM_006230771.3
Accession Version	XM_006230771.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	menin isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230771.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230833.1
CDS	110..1942
Translation	MGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREAEAAEAEEPWGDEAREGRRRGPRRESKPEEPPPPKKPALDKGPGSGQSAGSGPPRKTSGTVSGTARGTEVSSAAQAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL

Target ORF information:

RefSeq Version	XM_006230771.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus menin 1 (Men1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230771.3

ORF Insert Sequence:

ATGGGGCTGA AGGCCGCCCA GAAGACGCTG TTCCCTCTGC GCTCTATCGA CGACGTGGTG 
CGCCTGTTCG CTGCGGAGCT GGGCCGAGAG GAGCCTGACC TGGTGCTCCT CTCCTTGGTT 
CTGGGCTTCG TAGAGCATTT CCTGGCTGTC AACCGTGTCA TCCCCACCAA CGTGCCGGAG 
CTCACCTTCC AGCCCAGCCC GGCACCCGAC CCTCCTGGTG GCCTCACCTA CTTCCCAGTG 
GCCGACCTAT CCATCATTGC TGCCCTCTAT GCCCGATTCA CCGCTCAGAT CCGCGGTGCT 
GTGGACCTCT CCCTCTATCC TCGAGAGGGG GGCGTTTCCA GTCGCGAACT GGTAAAAAAG 
GTCTCGGATG TCATATGGAA CAGCCTCAGC CGCTCCTACT TCAAGGACCG GGCCCACATC 
CAGTCTCTCT TCAGCTTCAT CACAGGCACT AAACTGGACA GTTCGGGCGT GGCCTTTGCA 
GTGGTAGGGG CCTGCCAGGC TCTAGGTCTC AGAGATGTCC ATCTGGCCCT GTCCGAGGAT 
CATGCCTGGG TGGTGTTCGG GTCCAATGGG GAACAGACGG CTGAGGTGAC CTGGCATGGC 
AAAGGCAACG AGGACCGCAG AGGCCAGACA GTCAACGCTG GTGTGGCTGA GCGGAGCTGG 
CTGTACCTGA AAGGATCGTA CATGCGCTGT GACCGCAAGA TGGAGGTGGC GTTCATGGTG 
TGTGCCATCA ACCCTTCCAT TGATCTTCAC ACTGACTCTT TGGAACTGTT GCAACTACAG 
CAGAAGCTGC TCTGGCTGCT GTATGACCTA GGACATCTGG AAAGGTACCC CATGGCGCTA 
GGGAACTTGG CAGACCTGGA GGAGCTGGAA CCCACCCCTG GTCGGCCAGA CCCGCTCACC 
CTCTATCACA AGGGGATTGC CTCAGCTAAG ACCTACTACC AGGATGAACA CATCTACCCC 
TACATGTACC TGGCTGGATA CCATTGTCGC AACCGCAATG TGCGTGAAGC CCTGCAGGCC 
TGGGCCGACA CTGCCACTGT TATCCAAGAC TACAACTACT GTCGGGAGGA TGAAGAGATC 
TACAAGGAAT TCTTTGAAGT GGCCAATGAC GTCATCCCCA ACCTGCTGAA GGAGGCAGCC 
AGCCTGCTAG AAGCAGGCGA GGAGCGGCCA GGAGAGCAAG CCCAGGGCAC CCAAGGCCAA 
GGTTCTGCCC TCCAGGACCC AGAGTGCTTT GCCCACCTGC TGCGATTCTA TGATGGCATC 
TGCAAATGGG AGGAGGGTAG CCCCACACCA GTACTGCACG TGGGCTGGGC AACTTTCCTT 
GTGCAGTCCC TAGGACGCTT TGAGGGACAG GTGCGGCAGA AGGTGCACAT AGTTAGCCGG 
GAAGCCGAGG CAGCAGAGGC GGAAGAACCA TGGGGGGACG AAGCCCGAGA AGGTCGTCGG 
CGCGGTCCCC GCCGAGAGTC CAAGCCTGAG GAGCCACCAC CACCCAAGAA GCCTGCGTTG 
GACAAGGGCC CAGGCTCAGG GCAAAGTGCA GGGTCGGGAC CTCCTAGGAA AACGTCAGGG 
ACTGTCTCAG GTACTGCCCG TGGCACAGAA GTCAGCAGTG CTGCTCAGGC TCCAGCACCT 
GCAGCATCGC CACCCCCAGA GGGCCCAGTG CTCACTTTCC AGAGTGAGAA GATGAAAGGA 
ATGAAGGAGC TACTGGTGGC CACCAAGATC AACTCTAGTG CCATCAAGCT GCAACTCACG 
GCACAGTCCC AAGTGCAGAT GAAGAAACAG AAGGTGTCCA CACCCAGCGA CTACACACTC 
TCTTTCCTAA AGCGGCAGCG CAAGGGCCTC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Men1 ( XM_006230769.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006230831.1 Rattus norvegicus menin 1 (Men1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa23751
Clone ID Related Accession (Same CDS sequence)	XM_006230769.3
Accession Version	XM_006230769.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1851bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	menin isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006230769.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCACCGC CCGCCGCCAT GGGGCTGAAG GCCGCCCAGA AGACGCTGTT CCCTCTGCGC 
TCTATCGACG ACGTGGTGCG CCTGTTCGCT GCGGAGCTGG GCCGAGAGGA GCCTGACCTG 
GTGCTCCTCT CCTTGGTTCT GGGCTTCGTA GAGCATTTCC TGGCTGTCAA CCGTGTCATC 
CCCACCAACG TGCCGGAGCT CACCTTCCAG CCCAGCCCGG CACCCGACCC TCCTGGTGGC 
CTCACCTACT TCCCAGTGGC CGACCTATCC ATCATTGCTG CCCTCTATGC CCGATTCACC 
GCTCAGATCC GCGGTGCTGT GGACCTCTCC CTCTATCCTC GAGAGGGGGG CGTTTCCAGT 
CGCGAACTGG TAAAAAAGGT CTCGGATGTC ATATGGAACA GCCTCAGCCG CTCCTACTTC 
AAGGACCGGG CCCACATCCA GTCTCTCTTC AGCTTCATCA CAGGCACTAA ACTGGACAGT 
TCGGGCGTGG CCTTTGCAGT GGTAGGGGCC TGCCAGGCTC TAGGTCTCAG AGATGTCCAT 
CTGGCCCTGT CCGAGGATCA TGCCTGGGTG GTGTTCGGGT CCAATGGGGA ACAGACGGCT 
GAGGTGACCT GGCATGGCAA AGGCAACGAG GACCGCAGAG GCCAGACAGT CAACGCTGGT 
GTGGCTGAGC GGAGCTGGCT GTACCTGAAA GGATCGTACA TGCGCTGTGA CCGCAAGATG 
GAGGTGGCGT TCATGGTGTG TGCCATCAAC CCTTCCATTG ATCTTCACAC TGACTCTTTG 
GAACTGTTGC AACTACAGCA GAAGCTGCTC TGGCTGCTGT ATGACCTAGG ACATCTGGAA 
AGGTACCCCA TGGCGCTAGG GAACTTGGCA GACCTGGAGG AGCTGGAACC CACCCCTGGT 
CGGCCAGACC CGCTCACCCT CTATCACAAG GGGATTGCCT CAGCTAAGAC CTACTACCAG 
GATGAACACA TCTACCCCTA CATGTACCTG GCTGGATACC ATTGTCGCAA CCGCAATGTG 
CGTGAAGCCC TGCAGGCCTG GGCCGACACT GCCACTGTTA TCCAAGACTA CAACTACTGT 
CGGGAGGATG AAGAGATCTA CAAGGAATTC TTTGAAGTGG CCAATGACGT CATCCCCAAC 
CTGCTGAAGG AGGCAGCCAG CCTGCTAGAA GCAGGCGAGG AGCGGCCAGG AGAGCAAGCC 
CAGGGCACCC AAGGCCAAGG TTCTGCCCTC CAGGACCCAG AGTGCTTTGC CCACCTGCTG 
CGATTCTATG ATGGCATCTG CAAATGGGAG GAGGGTAGCC CCACACCAGT ACTGCACGTG 
GGCTGGGCAA CTTTCCTTGT GCAGTCCCTA GGACGCTTTG AGGGACAGGT GCGGCAGAAG 
GTGCACATAG TTAGCCGGGA AGCCGAGGCA GCAGAGGCGG AAGAACCATG GGGGGACGAA 
GCCCGAGAAG GTCGTCGGCG CGGTCCCCGC CGAGAGTCCA AGCCTGAGGA GCCACCACCA 
CCCAAGAAGC CTGCGTTGGA CAAGGGCCCA GGCTCAGGGC AAAGTGCAGG GTCGGGACCT 
CCTAGGAAAA CGTCAGGGAC TGTCTCAGGT ACTGCCCGTG GCACAGAAGT CAGCAGTGCT 
GCTCAGGCTC CAGCACCTGC AGCATCGCCA CCCCCAGAGG GCCCAGTGCT CACTTTCCAG 
AGTGAGAAGA TGAAAGGAAT GAAGGAGCTA CTGGTGGCCA CCAAGATCAA CTCTAGTGCC 
ATCAAGCTGC AACTCACGGC ACAGTCCCAA GTGCAGATGA AGAAACAGAA GGTGTCCACA 
CCCAGCGACT ACACACTCTC TTTCCTAAAG CGGCAGCGCA AGGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006230831.1
CDS	86..1936
Translation	MPPPAAMGLKAAQKTLFPLRSIDDVVRLFAAELGREEPDLVLLSLVLGFVEHFLAVNRVIPTNVPELTFQPSPAPDPPGGLTYFPVADLSIIAALYARFTAQIRGAVDLSLYPREGGVSSRELVKKVSDVIWNSLSRSYFKDRAHIQSLFSFITGTKLDSSGVAFAVVGACQALGLRDVHLALSEDHAWVVFGSNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFMVCAINPSIDLHTDSLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEELEPTPGRPDPLTLYHKGIASAKTYYQDEHIYPYMYLAGYHCRNRNVREALQAWADTATVIQDYNYCREDEEIYKEFFEVANDVIPNLLKEAASLLEAGEERPGEQAQGTQGQGSALQDPECFAHLLRFYDGICKWEEGSPTPVLHVGWATFLVQSLGRFEGQVRQKVHIVSREAEAAEAEEPWGDEAREGRRRGPRRESKPEEPPPPKKPALDKGPGSGQSAGSGPPRKTSGTVSGTARGTEVSSAAQAPAPAASPPPEGPVLTFQSEKMKGMKELLVATKINSSAIKLQLTAQSQVQMKKQKVSTPSDYTLSFLKRQRKGL

Target ORF information:

RefSeq Version	XM_006230769.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus menin 1 (Men1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006230769.3

ORF Insert Sequence:

ATGCCACCGC CCGCCGCCAT GGGGCTGAAG GCCGCCCAGA AGACGCTGTT CCCTCTGCGC 
TCTATCGACG ACGTGGTGCG CCTGTTCGCT GCGGAGCTGG GCCGAGAGGA GCCTGACCTG 
GTGCTCCTCT CCTTGGTTCT GGGCTTCGTA GAGCATTTCC TGGCTGTCAA CCGTGTCATC 
CCCACCAACG TGCCGGAGCT CACCTTCCAG CCCAGCCCGG CACCCGACCC TCCTGGTGGC 
CTCACCTACT TCCCAGTGGC CGACCTATCC ATCATTGCTG CCCTCTATGC CCGATTCACC 
GCTCAGATCC GCGGTGCTGT GGACCTCTCC CTCTATCCTC GAGAGGGGGG CGTTTCCAGT 
CGCGAACTGG TAAAAAAGGT CTCGGATGTC ATATGGAACA GCCTCAGCCG CTCCTACTTC 
AAGGACCGGG CCCACATCCA GTCTCTCTTC AGCTTCATCA CAGGCACTAA ACTGGACAGT 
TCGGGCGTGG CCTTTGCAGT GGTAGGGGCC TGCCAGGCTC TAGGTCTCAG AGATGTCCAT 
CTGGCCCTGT CCGAGGATCA TGCCTGGGTG GTGTTCGGGT CCAATGGGGA ACAGACGGCT 
GAGGTGACCT GGCATGGCAA AGGCAACGAG GACCGCAGAG GCCAGACAGT CAACGCTGGT 
GTGGCTGAGC GGAGCTGGCT GTACCTGAAA GGATCGTACA TGCGCTGTGA CCGCAAGATG 
GAGGTGGCGT TCATGGTGTG TGCCATCAAC CCTTCCATTG ATCTTCACAC TGACTCTTTG 
GAACTGTTGC AACTACAGCA GAAGCTGCTC TGGCTGCTGT ATGACCTAGG ACATCTGGAA 
AGGTACCCCA TGGCGCTAGG GAACTTGGCA GACCTGGAGG AGCTGGAACC CACCCCTGGT 
CGGCCAGACC CGCTCACCCT CTATCACAAG GGGATTGCCT CAGCTAAGAC CTACTACCAG 
GATGAACACA TCTACCCCTA CATGTACCTG GCTGGATACC ATTGTCGCAA CCGCAATGTG 
CGTGAAGCCC TGCAGGCCTG GGCCGACACT GCCACTGTTA TCCAAGACTA CAACTACTGT 
CGGGAGGATG AAGAGATCTA CAAGGAATTC TTTGAAGTGG CCAATGACGT CATCCCCAAC 
CTGCTGAAGG AGGCAGCCAG CCTGCTAGAA GCAGGCGAGG AGCGGCCAGG AGAGCAAGCC 
CAGGGCACCC AAGGCCAAGG TTCTGCCCTC CAGGACCCAG AGTGCTTTGC CCACCTGCTG 
CGATTCTATG ATGGCATCTG CAAATGGGAG GAGGGTAGCC CCACACCAGT ACTGCACGTG 
GGCTGGGCAA CTTTCCTTGT GCAGTCCCTA GGACGCTTTG AGGGACAGGT GCGGCAGAAG 
GTGCACATAG TTAGCCGGGA AGCCGAGGCA GCAGAGGCGG AAGAACCATG GGGGGACGAA 
GCCCGAGAAG GTCGTCGGCG CGGTCCCCGC CGAGAGTCCA AGCCTGAGGA GCCACCACCA 
CCCAAGAAGC CTGCGTTGGA CAAGGGCCCA GGCTCAGGGC AAAGTGCAGG GTCGGGACCT 
CCTAGGAAAA CGTCAGGGAC TGTCTCAGGT ACTGCCCGTG GCACAGAAGT CAGCAGTGCT 
GCTCAGGCTC CAGCACCTGC AGCATCGCCA CCCCCAGAGG GCCCAGTGCT CACTTTCCAG 
AGTGAGAAGA TGAAAGGAAT GAAGGAGCTA CTGGTGGCCA CCAAGATCAA CTCTAGTGCC 
ATCAAGCTGC AACTCACGGC ACAGTCCCAA GTGCAGATGA AGAAACAGAA GGTGTCCACA 
CCCAGCGACT ACACACTCTC TTTCCTAAAG CGGCAGCGCA AGGGCCTCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.
Oncogene34(7)932-8(2015 Feb)
Gillam MP,Nimbalkar D,Sun L,Christov K,Ray D,Kaldis P,Liu X,Kiyokawa H

Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation.
The Biochemical journal465(2)315-23(2015 Jan)
Ouyang M,Su W,Xiao L,Rao JN,Jiang L,Li Y,Turner DJ,Gorospe M,Wang JY

miR-24 regulates menin in the endocrine pancreas.
American journal of physiology. Endocrinology and metabolism307(1)E84-92(2014 Jul)
Vijayaraghavan J,Maggi EC,Crabtree JS

Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.
Endocrine-related cancer20(6)833-48(2013 Dec)
Hamze Z,Vercherat C,Bernigaud-Lacheretz A,Bazzi W,Bonnavion R,Lu J,Calender A,Pouponnot C,Bertolino P,Roche C,Stein R,Scoazec JY,Zhang CX,Cordier-Bussat M

HTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene.
Carcinogenesis34(11)2664-72(2013 Nov)
Borowiak M,Kuhlmann AS,Girard S,Gazzolo L,Mesnard JM,Jalinot P,Dodon MD

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Men1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

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Target ORF information:

ORF Insert Sequence:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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