Aire cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Aire
Entrez Gene ID	294328
Full Name	autoimmune regulator
General protein information	Preferred Names autoimmune regulator Names autoimmune regulator autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 20 Map Location: 20p12

mRNA and Protein(s)

mRNA	Protein	Name
XM_006256247.2	XP_006256309.1	autoimmune regulator isoform X1
XM_017601598.1	XP_017457087.1	autoimmune regulator isoform X3
XM_017601599.1	XP_017457088.1	autoimmune regulator isoform X4
XM_017601597.1	XP_017457086.1	autoimmune regulator isoform X2
XM_017601600.1	XP_017457089.1	autoimmune regulator isoform X5
XM_017601602.1	XP_017457091.1	autoimmune regulator isoform X7
XM_017601601.1	XP_017457090.1	autoimmune regulator isoform X6
NM_001106379.1	NP_001099849.1	autoimmune regulator

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	AIRE	XP_531580.1
Bos taurus (cattle)	AIRE	XP_002685182.2
Rattus norvegicus (Norway rat)	Aire	NP_001099849.1
	AIRE	XP_001103602.2
Canis lupus familiaris (dog)	AIRE	XP_544921.3
Homo sapiens (human)	AIRE	NP_000374.1
Mus musculus (house mouse)	Aire	NP_001258478.1
Danio rerio (zebrafish)	aire	NP_001103484.1

Gene Ontology
Bibliography

Related articles in PubMed

Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Oftedal BE, Hellesen A, Erichsen MM, Bratland E, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WA, Sozaeva LS, Zayats T, Haugarvoll K, Orlova EM, Haavik J, Johansson S, Knappskog PM, L?v?s K, Wolff AS, Abramson J, Husebye ES
Immunity42(6)1185-96(2015 Jun)

Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4? T cells.
Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS
Immunity39(3)560-72(2013 Sep)

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance.
Aichinger M, Wu C, Nedjic J, Klein L
The Journal of experimental medicine210(2)287-300(2013 Feb)

Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes.
Laan M, Kisand K, Kont V, M?ll K, Tserel L, Scott HS, Peterson P
Journal of immunology (Baltimore, Md. : 1950)183(12)7682-91(2009 Dec)

Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator.
Chakravarty S, Zeng L, Zhou MM
Structure (London, England : 1993)17(5)670-9(2009 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Aire gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Aire cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa10931	NM_001106379.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$321.30 $459.00
ORa39334	XM_006256247.2 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
ORa60069	XM_017601599.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa60070	XM_017601600.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa60071	XM_017601601.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa60072	XM_017601602.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
ORa60067	XM_017601597.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
ORa60068	XM_017601598.1 Latest version!	Rattus norvegicus autoimmune regulator (Aire), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Aire ( NM_001106379.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001099849.1 Rattus norvegicus autoimmune regulator (Aire), mRNA.

Price & Availability↑

CloneID	ORa10931
Clone ID Related Accession (Same CDS sequence)	NM_001106379.1
Accession Version	NM_001106379.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1644bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473988.1. On or before Oct 4, 2007 this sequence version replaced XM_228067.4, XM_001071453.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAAGAACG AGGATGAATG CGCTGTGTGC 
CATGACGGAG GCGAGCTCAT CTGCTGTGAC GGCTGTCCCC GCGCCTTCCA CCTGGCTTGC 
CTGTCCCCAC CTCTGCAGGA GATCCCCAGT GGCCTTTGGA GATGTTCGTG CTGCCTCCAG 
GGCAGAATCC AGCAGAACCT GTCCCAGCCT GAGGAGTCCA GGCCCCTGGA GCCATCTGCA 
GAGACCCCGA TTCTCCTGGG ACTGAGGTCA GCTTCCGAGA AAACCAGGGT CCTGTCCAGG 
GAGCTGCCAG CCGGCTCAGA TGCTGCAGTC ACATATGCGA ACCTGCTGGC CCCACCTTCC 
ACAGCCCCTG TTCTGGAGCC TTCAGCACTC TGCCCTCTAC CGAGTGCTGG GGCGGAAGGG 
CAGCCGGGTC CGACACTGAG CGCGCGATGC GGTGTGTGCG GCGACTCCAC CGACGTGCTG 
CGGTGCGCAC ACTGTGCCGC TGCCTTTCAC TGGCGCTGCC ACTTCCCGAT GGCTGCTGTC 
CGGCCAGGGA CCAATCTCCG CTGCAAGTCC TGCTCGGCAG AACCGACTCC CACGCCAGGC 
GTGCCAGGCG AGGCTGTGCC CACCGCTGTG CGTCCCACAC CTGGGCTTGC CAAGGTAGGG 
GACGACTCTG CTAGTCATGA CCCTGTTCTG CATAGGGATG ACCTGGAGTC CCTCCTGAAT 
GAGCACTCCT TTGACGGCAT CCTGCAGTGG GCCATCCAGA GCATGTCACG CCCGCTGGCC 
GAGACACCAC CCTTTTCTTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001099849.1
CDS	59..1702
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQGRDEQKVSQQCGVPPLPPLPNEPQVHQKNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPILLGLRSASEKTRVLSRELPAGSDAAVTYANLLAPPSTAPVLEPSALCPLPSAGAEGQPGPTLSARCGVCGDSTDVLRCAHCAAAFHWRCHFPMAAVRPGTNLRCKSCSAEPTPTPGVPGEAVPTAVRPTPGLAKVGDDSASHDPVLHRDDLESLLNEHSFDGILQWAIQSMSRPLAETPPFSS

Target ORF information:

RefSeq Version	NM_001106379.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106379.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAAGAACG AGGATGAATG CGCTGTGTGC 
CATGACGGAG GCGAGCTCAT CTGCTGTGAC GGCTGTCCCC GCGCCTTCCA CCTGGCTTGC 
CTGTCCCCAC CTCTGCAGGA GATCCCCAGT GGCCTTTGGA GATGTTCGTG CTGCCTCCAG 
GGCAGAATCC AGCAGAACCT GTCCCAGCCT GAGGAGTCCA GGCCCCTGGA GCCATCTGCA 
GAGACCCCGA TTCTCCTGGG ACTGAGGTCA GCTTCCGAGA AAACCAGGGT CCTGTCCAGG 
GAGCTGCCAG CCGGCTCAGA TGCTGCAGTC ACATATGCGA ACCTGCTGGC CCCACCTTCC 
ACAGCCCCTG TTCTGGAGCC TTCAGCACTC TGCCCTCTAC CGAGTGCTGG GGCGGAAGGG 
CAGCCGGGTC CGACACTGAG CGCGCGATGC GGTGTGTGCG GCGACTCCAC CGACGTGCTG 
CGGTGCGCAC ACTGTGCCGC TGCCTTTCAC TGGCGCTGCC ACTTCCCGAT GGCTGCTGTC 
CGGCCAGGGA CCAATCTCCG CTGCAAGTCC TGCTCGGCAG AACCGACTCC CACGCCAGGC 
GTGCCAGGCG AGGCTGTGCC CACCGCTGTG CGTCCCACAC CTGGGCTTGC CAAGGTAGGG 
GACGACTCTG CTAGTCATGA CCCTGTTCTG CATAGGGATG ACCTGGAGTC CCTCCTGAAT 
GAGCACTCCT TTGACGGCAT CCTGCAGTGG GCCATCCAGA GCATGTCACG CCCGCTGGCC 
GAGACACCAC CCTTTTCTTC CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_006256247.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006256309.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa39334
Clone ID Related Accession (Same CDS sequence)	XM_006256247.2
Accession Version	XM_006256247.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006256247.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAAGAA CGAGGATGAA 
TGCGCTGTGT GCCATGACGG AGGCGAGCTC ATCTGCTGTG ACGGCTGTCC CCGCGCCTTC 
CACCTGGCTT GCCTGTCCCC ACCTCTGCAG GAGATCCCCA GTGGCCTTTG GAGATGTTCG 
TGCTGCCTCC AGGGCAGAAT CCAGCAGAAC CTGTCCCAGC CTGAGGAGTC CAGGCCCCTG 
GAGCCATCTG CAGAGACCCC GATTCTCCTG GGACTGAGGT CAGCTTCCGA GAAAACCAGG 
GTCCTGTCCA GGGAGCTGCC AGCCGGCTCA GATGCTGCAG TCACATATGC GAACCTGCTG 
GCCCCACCTT CCACAGCCCC TGTTCTGGAG CCTTCAGCAC TCTGCCCTCT ACCGAGTGCT 
GGGGCGGAAG GGCAGCCGGG TCCGACACTG AGCGCGCGAT GCGGTGTGTG CGGCGACTCC 
ACCGACGTGC TGCGGTGCGC ACACTGTGCC GCTGCCTTTC ACTGGCGCTG CCACTTCCCG 
ATGGCTGCTG TCCGGCCAGG GACCAATCTC CGCTGCAAGT CCTGCTCGGC AGAACCGACT 
CCCACGCCAG GCGTGCCAGG CGAGGCTGTG CCCACCGCTG TGCGTCCCAC ACCTGGGCTT 
GCCAAGGTAG GGGACGACTC TGCTAGTCAT GACCCTGTTC TGCATAGGGA TGACCTGGAG 
TCCCTCCTGA ATGAGCACTC CTTTGACGGC ATCCTGCAGT GGGCCATCCA GAGCATGTCA 
CGCCCGCTGG CCGAGACACC ACCCTTTTCT TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006256309.1
CDS	126..1781
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQVTIPGRDEQKVSQQCGVPPLPPLPNEPQVHQKNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPILLGLRSASEKTRVLSRELPAGSDAAVTYANLLAPPSTAPVLEPSALCPLPSAGAEGQPGPTLSARCGVCGDSTDVLRCAHCAAAFHWRCHFPMAAVRPGTNLRCKSCSAEPTPTPGVPGEAVPTAVRPTPGLAKVGDDSASHDPVLHRDDLESLLNEHSFDGILQWAIQSMSRPLAETPPFSS

Target ORF information:

RefSeq Version	XM_006256247.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006256247.2

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAAGAA CGAGGATGAA 
TGCGCTGTGT GCCATGACGG AGGCGAGCTC ATCTGCTGTG ACGGCTGTCC CCGCGCCTTC 
CACCTGGCTT GCCTGTCCCC ACCTCTGCAG GAGATCCCCA GTGGCCTTTG GAGATGTTCG 
TGCTGCCTCC AGGGCAGAAT CCAGCAGAAC CTGTCCCAGC CTGAGGAGTC CAGGCCCCTG 
GAGCCATCTG CAGAGACCCC GATTCTCCTG GGACTGAGGT CAGCTTCCGA GAAAACCAGG 
GTCCTGTCCA GGGAGCTGCC AGCCGGCTCA GATGCTGCAG TCACATATGC GAACCTGCTG 
GCCCCACCTT CCACAGCCCC TGTTCTGGAG CCTTCAGCAC TCTGCCCTCT ACCGAGTGCT 
GGGGCGGAAG GGCAGCCGGG TCCGACACTG AGCGCGCGAT GCGGTGTGTG CGGCGACTCC 
ACCGACGTGC TGCGGTGCGC ACACTGTGCC GCTGCCTTTC ACTGGCGCTG CCACTTCCCG 
ATGGCTGCTG TCCGGCCAGG GACCAATCTC CGCTGCAAGT CCTGCTCGGC AGAACCGACT 
CCCACGCCAG GCGTGCCAGG CGAGGCTGTG CCCACCGCTG TGCGTCCCAC ACCTGGGCTT 
GCCAAGGTAG GGGACGACTC TGCTAGTCAT GACCCTGTTC TGCATAGGGA TGACCTGGAG 
TCCCTCCTGA ATGAGCACTC CTTTGACGGC ATCCTGCAGT GGGCCATCCA GAGCATGTCA 
CGCCCGCTGG CCGAGACACC ACCCTTTTCT TCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_017601599.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457088.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X4, mRNA.

Price & Availability↑

CloneID	ORa60069
Clone ID Related Accession (Same CDS sequence)	XM_017601599.1
Accession Version	XM_017601599.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAAGAA CGAGGATGAA 
TGCGCTGTGT GCCATGACGG AGGCGAGCTC ATCTGCTGTG ACGGCTGTCC CCGCGCCTTC 
CACCTGGCTT GCCTGTCCCC ACCTCTGCAG GAGATCCCCA GTGGCCTTTG GAGATGTTCG 
TGCTGCCTCC AGGGCAGAAT CCAGCAGAAC CTGTCCCAGC CTGAGGAGTC CAGGCCCCTG 
GAGCCATCTG CAGAGACCCC GGACCAATCT CCGCTGCAAG TCCTGCTCGG CAGAACCGAC 
TCCCACGCCA GGCGTGCCAG GCGAGGCTGT GCCCACCGCT GTGCGTCCCA CACCTGGGCT 
TGCCAAGGTA GGGGACGACT CTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457088.1
CDS	126..1352
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQVTIPGRDEQKVSQQCGVPPLPPLPNEPQVHQKNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPDQSPLQVLLGRTDSHARRARRGCAHRCASHTWACQGRGRLC

Target ORF information:

RefSeq Version	XM_017601599.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601599.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAAGAA CGAGGATGAA 
TGCGCTGTGT GCCATGACGG AGGCGAGCTC ATCTGCTGTG ACGGCTGTCC CCGCGCCTTC 
CACCTGGCTT GCCTGTCCCC ACCTCTGCAG GAGATCCCCA GTGGCCTTTG GAGATGTTCG 
TGCTGCCTCC AGGGCAGAAT CCAGCAGAAC CTGTCCCAGC CTGAGGAGTC CAGGCCCCTG 
GAGCCATCTG CAGAGACCCC GGACCAATCT CCGCTGCAAG TCCTGCTCGG CAGAACCGAC 
TCCCACGCCA GGCGTGCCAG GCGAGGCTGT GCCCACCGCT GTGCGTCCCA CACCTGGGCT 
TGCCAAGGTA GGGGACGACT CTGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_017601600.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457089.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X5, mRNA.

Price & Availability↑

CloneID	ORa60070
Clone ID Related Accession (Same CDS sequence)	XM_017601600.1
Accession Version	XM_017601600.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1224bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X5
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAACGA GGATGAATGC 
GCTGTGTGCC ATGACGGAGG CGAGCTCATC TGCTGTGACG GCTGTCCCCG CGCCTTCCAC 
CTGGCTTGCC TGTCCCCACC TCTGCAGGAG ATCCCCAGTG GCCTTTGGAG ATGTTCGTGC 
TGCCTCCAGG GCAGAATCCA GCAGAACCTG TCCCAGCCTG AGGAGTCCAG GCCCCTGGAG 
CCATCTGCAG AGACCCCGGA CCAATCTCCG CTGCAAGTCC TGCTCGGCAG AACCGACTCC 
CACGCCAGGC GTGCCAGGCG AGGCTGTGCC CACCGCTGTG CGTCCCACAC CTGGGCTTGC 
CAAGGTAGGG GACGACTCTG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457089.1
CDS	126..1349
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQVTIPGRDEQKVSQQCGVPPLPPLPNEPQVHQNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPDQSPLQVLLGRTDSHARRARRGCAHRCASHTWACQGRGRLC

Target ORF information:

RefSeq Version	XM_017601600.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601600.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAACGA GGATGAATGC 
GCTGTGTGCC ATGACGGAGG CGAGCTCATC TGCTGTGACG GCTGTCCCCG CGCCTTCCAC 
CTGGCTTGCC TGTCCCCACC TCTGCAGGAG ATCCCCAGTG GCCTTTGGAG ATGTTCGTGC 
TGCCTCCAGG GCAGAATCCA GCAGAACCTG TCCCAGCCTG AGGAGTCCAG GCCCCTGGAG 
CCATCTGCAG AGACCCCGGA CCAATCTCCG CTGCAAGTCC TGCTCGGCAG AACCGACTCC 
CACGCCAGGC GTGCCAGGCG AGGCTGTGCC CACCGCTGTG CGTCCCACAC CTGGGCTTGC 
CAAGGTAGGG GACGACTCTG CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_017601601.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457090.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X6, mRNA.

Price & Availability↑

CloneID	ORa60071
Clone ID Related Accession (Same CDS sequence)	XM_017601601.1
Accession Version	XM_017601601.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1215bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X6
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAAGAACG AGGATGAATG CGCTGTGTGC 
CATGACGGAG GCGAGCTCAT CTGCTGTGAC GGCTGTCCCC GCGCCTTCCA CCTGGCTTGC 
CTGTCCCCAC CTCTGCAGGA GATCCCCAGT GGCCTTTGGA GATGTTCGTG CTGCCTCCAG 
GGCAGAATCC AGCAGAACCT GTCCCAGCCT GAGGAGTCCA GGCCCCTGGA GCCATCTGCA 
GAGACCCCGG ACCAATCTCC GCTGCAAGTC CTGCTCGGCA GAACCGACTC CCACGCCAGG 
CGTGCCAGGC GAGGCTGTGC CCACCGCTGT GCGTCCCACA CCTGGGCTTG CCAAGGTAGG 
GGACGACTCT GCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457090.1
CDS	126..1340
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQGRDEQKVSQQCGVPPLPPLPNEPQVHQKNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPDQSPLQVLLGRTDSHARRARRGCAHRCASHTWACQGRGRLC

Target ORF information:

RefSeq Version	XM_017601601.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601601.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAAGAACG AGGATGAATG CGCTGTGTGC 
CATGACGGAG GCGAGCTCAT CTGCTGTGAC GGCTGTCCCC GCGCCTTCCA CCTGGCTTGC 
CTGTCCCCAC CTCTGCAGGA GATCCCCAGT GGCCTTTGGA GATGTTCGTG CTGCCTCCAG 
GGCAGAATCC AGCAGAACCT GTCCCAGCCT GAGGAGTCCA GGCCCCTGGA GCCATCTGCA 
GAGACCCCGG ACCAATCTCC GCTGCAAGTC CTGCTCGGCA GAACCGACTC CCACGCCAGG 
CGTGCCAGGC GAGGCTGTGC CCACCGCTGT GCGTCCCACA CCTGGGCTTG CCAAGGTAGG 
GGACGACTCT GCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_017601602.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457091.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X7, mRNA.

Price & Availability↑

CloneID	ORa60072
Clone ID Related Accession (Same CDS sequence)	XM_017601602.1
Accession Version	XM_017601602.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X7
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAACGAGG ATGAATGCGC TGTGTGCCAT 
GACGGAGGCG AGCTCATCTG CTGTGACGGC TGTCCCCGCG CCTTCCACCT GGCTTGCCTG 
TCCCCACCTC TGCAGGAGAT CCCCAGTGGC CTTTGGAGAT GTTCGTGCTG CCTCCAGGGC 
AGAATCCAGC AGAACCTGTC CCAGCCTGAG GAGTCCAGGC CCCTGGAGCC ATCTGCAGAG 
ACCCCGGACC AATCTCCGCT GCAAGTCCTG CTCGGCAGAA CCGACTCCCA CGCCAGGCGT 
GCCAGGCGAG GCTGTGCCCA CCGCTGTGCG TCCCACACCT GGGCTTGCCA AGGTAGGGGA 
CGACTCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457091.1
CDS	126..1337
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQGRDEQKVSQQCGVPPLPPLPNEPQVHQNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPDQSPLQVLLGRTDSHARRARRGCAHRCASHTWACQGRGRLC

Target ORF information:

RefSeq Version	XM_017601602.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601602.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAACGAGG ATGAATGCGC TGTGTGCCAT 
GACGGAGGCG AGCTCATCTG CTGTGACGGC TGTCCCCGCG CCTTCCACCT GGCTTGCCTG 
TCCCCACCTC TGCAGGAGAT CCCCAGTGGC CTTTGGAGAT GTTCGTGCTG CCTCCAGGGC 
AGAATCCAGC AGAACCTGTC CCAGCCTGAG GAGTCCAGGC CCCTGGAGCC ATCTGCAGAG 
ACCCCGGACC AATCTCCGCT GCAAGTCCTG CTCGGCAGAA CCGACTCCCA CGCCAGGCGT 
GCCAGGCGAG GCTGTGCCCA CCGCTGTGCG TCCCACACCT GGGCTTGCCA AGGTAGGGGA 
CGACTCTGCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_017601597.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457086.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa60067
Clone ID Related Accession (Same CDS sequence)	XM_017601597.1
Accession Version	XM_017601597.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1653bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAACGA GGATGAATGC 
GCTGTGTGCC ATGACGGAGG CGAGCTCATC TGCTGTGACG GCTGTCCCCG CGCCTTCCAC 
CTGGCTTGCC TGTCCCCACC TCTGCAGGAG ATCCCCAGTG GCCTTTGGAG ATGTTCGTGC 
TGCCTCCAGG GCAGAATCCA GCAGAACCTG TCCCAGCCTG AGGAGTCCAG GCCCCTGGAG 
CCATCTGCAG AGACCCCGAT TCTCCTGGGA CTGAGGTCAG CTTCCGAGAA AACCAGGGTC 
CTGTCCAGGG AGCTGCCAGC CGGCTCAGAT GCTGCAGTCA CATATGCGAA CCTGCTGGCC 
CCACCTTCCA CAGCCCCTGT TCTGGAGCCT TCAGCACTCT GCCCTCTACC GAGTGCTGGG 
GCGGAAGGGC AGCCGGGTCC GACACTGAGC GCGCGATGCG GTGTGTGCGG CGACTCCACC 
GACGTGCTGC GGTGCGCACA CTGTGCCGCT GCCTTTCACT GGCGCTGCCA CTTCCCGATG 
GCTGCTGTCC GGCCAGGGAC CAATCTCCGC TGCAAGTCCT GCTCGGCAGA ACCGACTCCC 
ACGCCAGGCG TGCCAGGCGA GGCTGTGCCC ACCGCTGTGC GTCCCACACC TGGGCTTGCC 
AAGGTAGGGG ACGACTCTGC TAGTCATGAC CCTGTTCTGC ATAGGGATGA CCTGGAGTCC 
CTCCTGAATG AGCACTCCTT TGACGGCATC CTGCAGTGGG CCATCCAGAG CATGTCACGC 
CCGCTGGCCG AGACACCACC CTTTTCTTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457086.1
CDS	126..1778
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQVTIPGRDEQKVSQQCGVPPLPPLPNEPQVHQNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPILLGLRSASEKTRVLSRELPAGSDAAVTYANLLAPPSTAPVLEPSALCPLPSAGAEGQPGPTLSARCGVCGDSTDVLRCAHCAAAFHWRCHFPMAAVRPGTNLRCKSCSAEPTPTPGVPGEAVPTAVRPTPGLAKVGDDSASHDPVLHRDDLESLLNEHSFDGILQWAIQSMSRPLAETPPFSS

Target ORF information:

RefSeq Version	XM_017601597.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601597.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGTCACTAT ACCTGGTAGA GATGAGCAGA AAGTGAGCCA GCAGTGTGGG 
GTCCCTCCCC TTCCACCTCT TCCCAATGAG CCCCAAGTTC ACCAGAACGA GGATGAATGC 
GCTGTGTGCC ATGACGGAGG CGAGCTCATC TGCTGTGACG GCTGTCCCCG CGCCTTCCAC 
CTGGCTTGCC TGTCCCCACC TCTGCAGGAG ATCCCCAGTG GCCTTTGGAG ATGTTCGTGC 
TGCCTCCAGG GCAGAATCCA GCAGAACCTG TCCCAGCCTG AGGAGTCCAG GCCCCTGGAG 
CCATCTGCAG AGACCCCGAT TCTCCTGGGA CTGAGGTCAG CTTCCGAGAA AACCAGGGTC 
CTGTCCAGGG AGCTGCCAGC CGGCTCAGAT GCTGCAGTCA CATATGCGAA CCTGCTGGCC 
CCACCTTCCA CAGCCCCTGT TCTGGAGCCT TCAGCACTCT GCCCTCTACC GAGTGCTGGG 
GCGGAAGGGC AGCCGGGTCC GACACTGAGC GCGCGATGCG GTGTGTGCGG CGACTCCACC 
GACGTGCTGC GGTGCGCACA CTGTGCCGCT GCCTTTCACT GGCGCTGCCA CTTCCCGATG 
GCTGCTGTCC GGCCAGGGAC CAATCTCCGC TGCAAGTCCT GCTCGGCAGA ACCGACTCCC 
ACGCCAGGCG TGCCAGGCGA GGCTGTGCCC ACCGCTGTGC GTCCCACACC TGGGCTTGCC 
AAGGTAGGGG ACGACTCTGC TAGTCATGAC CCTGTTCTGC ATAGGGATGA CCTGGAGTCC 
CTCCTGAATG AGCACTCCTT TGACGGCATC CTGCAGTGGG CCATCCAGAG CATGTCACGC 
CCGCTGGCCG AGACACCACC CTTTTCTTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Aire ( XM_017601598.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017457087.1 Rattus norvegicus autoimmune regulator (Aire), transcript variant X3, mRNA.

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CloneID	ORa60068
Clone ID Related Accession (Same CDS sequence)	XM_017601598.1
Accession Version	XM_017601598.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1641bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	autoimmune regulator isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005119.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAACGAGG ATGAATGCGC TGTGTGCCAT 
GACGGAGGCG AGCTCATCTG CTGTGACGGC TGTCCCCGCG CCTTCCACCT GGCTTGCCTG 
TCCCCACCTC TGCAGGAGAT CCCCAGTGGC CTTTGGAGAT GTTCGTGCTG CCTCCAGGGC 
AGAATCCAGC AGAACCTGTC CCAGCCTGAG GAGTCCAGGC CCCTGGAGCC ATCTGCAGAG 
ACCCCGATTC TCCTGGGACT GAGGTCAGCT TCCGAGAAAA CCAGGGTCCT GTCCAGGGAG 
CTGCCAGCCG GCTCAGATGC TGCAGTCACA TATGCGAACC TGCTGGCCCC ACCTTCCACA 
GCCCCTGTTC TGGAGCCTTC AGCACTCTGC CCTCTACCGA GTGCTGGGGC GGAAGGGCAG 
CCGGGTCCGA CACTGAGCGC GCGATGCGGT GTGTGCGGCG ACTCCACCGA CGTGCTGCGG 
TGCGCACACT GTGCCGCTGC CTTTCACTGG CGCTGCCACT TCCCGATGGC TGCTGTCCGG 
CCAGGGACCA ATCTCCGCTG CAAGTCCTGC TCGGCAGAAC CGACTCCCAC GCCAGGCGTG 
CCAGGCGAGG CTGTGCCCAC CGCTGTGCGT CCCACACCTG GGCTTGCCAA GGTAGGGGAC 
GACTCTGCTA GTCATGACCC TGTTCTGCAT AGGGATGACC TGGAGTCCCT CCTGAATGAG 
CACTCCTTTG ACGGCATCCT GCAGTGGGCC ATCCAGAGCA TGTCACGCCC GCTGGCCGAG 
ACACCACCCT TTTCTTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017457087.1
CDS	126..1766
Translation	MAGGDGMLRRLLRLHRTEIAVAIDSAFPLLHALADHDVVPEDKFQETLRLKEKEGCPQAFHALLSWLLTRDSGAILDFWRVLFKDYNLERYSRLHTILDGFPKDVDLSQPRKGRKPLAGPKASVVPPRPPTKRRALEEPRATPPATLASKSISSPGSHSKAKPPKKPEGNLESQRLPLGNGIQTMAASVQRAVTVSSGDVPGSRGAVEGILIQQVFESGGSKKCIQVGGEFYKPSKFEDPSGNLKNKTRGGSSLKPVIRGKGTQGRDEQKVSQQCGVPPLPPLPNEPQVHQNEDECAVCHDGGELICCDGCPRAFHLACLSPPLQEIPSGLWRCSCCLQGRIQQNLSQPEESRPLEPSAETPILLGLRSASEKTRVLSRELPAGSDAAVTYANLLAPPSTAPVLEPSALCPLPSAGAEGQPGPTLSARCGVCGDSTDVLRCAHCAAAFHWRCHFPMAAVRPGTNLRCKSCSAEPTPTPGVPGEAVPTAVRPTPGLAKVGDDSASHDPVLHRDDLESLLNEHSFDGILQWAIQSMSRPLAETPPFSS

Target ORF information:

RefSeq Version	XM_017601598.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus autoimmune regulator (Aire), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017601598.1

ORF Insert Sequence:

ATGGCTGGTG GGGATGGGAT GCTGCGCCGC CTGCTGAGGC TGCACCGCAC CGAGATCGCA 
GTGGCCATAG ACAGCGCCTT TCCGCTGCTG CATGCTCTGG CCGACCACGA CGTGGTCCCT 
GAGGACAAGT TCCAGGAGAC ACTCCGGCTG AAAGAGAAGG AAGGCTGCCC CCAGGCCTTC 
CACGCCCTGC TGTCCTGGCT CCTGACTCGG GACAGTGGGG CCATCCTGGA TTTCTGGAGG 
GTTCTCTTTA AGGACTACAA TCTGGAGCGG TACAGCCGCC TGCATACCAT CCTGGACGGC 
TTTCCAAAAG ATGTGGACCT TAGCCAGCCT CGGAAAGGGA GGAAGCCCCT TGCTGGTCCC 
AAGGCTTCAG TAGTGCCACC CAGACCCCCC ACAAAGAGAA GAGCCCTGGA AGAGCCTCGA 
GCCACCCCAC CAGCAACTCT GGCCTCAAAG AGCATCTCTA GCCCAGGTTC CCACTCAAAG 
GCCAAACCCC CTAAGAAGCC AGAGGGCAAC TTGGAGTCAC AGCGCCTCCC ACTGGGAAAC 
GGAATCCAGA CCATGGCAGC TTCTGTCCAG AGAGCTGTGA CTGTGTCCTC CGGGGATGTC 
CCAGGATCCC GAGGGGCTGT GGAAGGGATC CTTATCCAGC AAGTATTCGA GTCAGGAGGA 
TCCAAGAAGT GCATCCAGGT TGGAGGGGAG TTTTATAAAC CCAGCAAGTT CGAAGACCCC 
AGTGGCAATT TGAAGAACAA GACCCGAGGT GGTAGCAGCC TAAAGCCAGT GATCCGAGGA 
AAGGGAACCC AGGGTAGAGA TGAGCAGAAA GTGAGCCAGC AGTGTGGGGT CCCTCCCCTT 
CCACCTCTTC CCAATGAGCC CCAAGTTCAC CAGAACGAGG ATGAATGCGC TGTGTGCCAT 
GACGGAGGCG AGCTCATCTG CTGTGACGGC TGTCCCCGCG CCTTCCACCT GGCTTGCCTG 
TCCCCACCTC TGCAGGAGAT CCCCAGTGGC CTTTGGAGAT GTTCGTGCTG CCTCCAGGGC 
AGAATCCAGC AGAACCTGTC CCAGCCTGAG GAGTCCAGGC CCCTGGAGCC ATCTGCAGAG 
ACCCCGATTC TCCTGGGACT GAGGTCAGCT TCCGAGAAAA CCAGGGTCCT GTCCAGGGAG 
CTGCCAGCCG GCTCAGATGC TGCAGTCACA TATGCGAACC TGCTGGCCCC ACCTTCCACA 
GCCCCTGTTC TGGAGCCTTC AGCACTCTGC CCTCTACCGA GTGCTGGGGC GGAAGGGCAG 
CCGGGTCCGA CACTGAGCGC GCGATGCGGT GTGTGCGGCG ACTCCACCGA CGTGCTGCGG 
TGCGCACACT GTGCCGCTGC CTTTCACTGG CGCTGCCACT TCCCGATGGC TGCTGTCCGG 
CCAGGGACCA ATCTCCGCTG CAAGTCCTGC TCGGCAGAAC CGACTCCCAC GCCAGGCGTG 
CCAGGCGAGG CTGTGCCCAC CGCTGTGCGT CCCACACCTG GGCTTGCCAA GGTAGGGGAC 
GACTCTGCTA GTCATGACCC TGTTCTGCAT AGGGATGACC TGGAGTCCCT CCTGAATGAG 
CACTCCTTTG ACGGCATCCT GCAGTGGGCC ATCCAGAGCA TGTCACGCCC GCTGGCCGAG 
ACACCACCCT TTTCTTCCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases.
Immunity42(6)1185-96(2015 Jun)
Oftedal BE,Hellesen A,Erichsen MM,Bratland E,Vardi A,Perheentupa J,Kemp EH,Fiskerstrand T,Viken MK,Weetman AP,Fleishman SJ,Banka S,Newman WG,Sewell WA,Sozaeva LS,Zayats T,Haugarvoll K,Orlova EM,Haavik J,Johansson S,Knappskog PM,L?v?s K,Wolff AS,Abramson J,Husebye ES

Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4? T cells.
Immunity39(3)560-72(2013 Sep)
Gardner JM,Metzger TC,McMahon EJ,Au-Yeung BB,Krawisz AK,Lu W,Price JD,Johannes KP,Satpathy AT,Murphy KM,Tarbell KV,Weiss A,Anderson MS

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance.
The Journal of experimental medicine210(2)287-300(2013 Feb)
Aichinger M,Wu C,Nedjic J,Klein L

Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes.
Journal of immunology (Baltimore, Md. : 1950)183(12)7682-91(2009 Dec)
Laan M,Kisand K,Kont V,M?ll K,Tserel L,Scott HS,Peterson P

Structure and site-specific recognition of histone H3 by the PHD finger of human autoimmune regulator.
Structure (London, England : 1993)17(5)670-9(2009 May)
Chakravarty S,Zeng L,Zhou MM

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Aire cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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