Gene Symbol | Rhoc |
Entrez Gene ID | 295342 |
Full Name | ras homolog family member C |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Rhoc cDNA ORF clone
Gene Symbol | Rhoc |
Entrez Gene ID | 295342 |
Full Name | ras homolog family member C |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001106461.1 | NP_001099931.1 | rho-related GTP-binding protein RhoC |
XM_006233074.1 | XP_006233136.1 | rho-related GTP-binding protein RhoC isoform X1 |
Canis lupus familiaris (dog) | RHOC | XP_540336.2 |
Danio rerio (zebrafish) | rhoad | NP_001002445.1 |
Danio rerio (zebrafish) | rhoac | NP_998515.1 |
Danio rerio (zebrafish) | rhoae | NP_957444.1 |
Bos taurus (cattle) | RHOC | NP_001039603.1 |
Xenopus tropicalis (tropical clawed frog) | rhoc | NP_001016569.1 |
Homo sapiens (human) | RHOC | NP_001036143.1 |
Pan troglodytes (chimpanzee) | RHOC | XP_003339043.1 |
Mus musculus (house mouse) | Rhoc | NP_031510.2 |
Rattus norvegicus (Norway rat) | Rhoc | NP_001099931.1 |
Gallus gallus (chicken) | RHOC | NP_001025020.1 |
Danio rerio (zebrafish) | rhoaa | NP_998302.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005160 | XP_001688510.1 |
Caenorhabditis elegans (roundworm) | rho-1 | NP_502959.1 |
Eremothecium gossypii | AGOS_ABR182W | NP_983130.1 |
Drosophila melanogaster (fruit fly) | Rho1 | NP_995851.1 |
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function.
Zhao B, Wu Z, M?ller U
eLife5(2016 06)
Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration.
Hsu SP, Chen TH, Chou YP, Chen LC, Kuo CT, Lee TS, Lin JJ, Chang NC, Lee WS
Atherosclerosis217(1)83-9(2011 Jul)
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.
Bravo-Cordero JJ, Oser M, Chen X, Eddy R, Hodgson L, Condeelis J
Current biology : CB21(8)635-44(2011 Apr)
The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells.
Wallace SW, Magalhaes A, Hall A
Molecular and cellular biology31(1)81-91(2011 Jan)
Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma.
Jiang L, Liu X, Kolokythas A, Yu J, Wang A, Heidbreder CE, Shi F, Zhou X
International journal of cancer127(3)505-12(2010 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
RhoC activity is spatially confined to areas surrounding invadopodia; it is controlled by "spatially distinct regulatory elements" that confine RhoC activation within this compartment. RhoC activation enhances cofilin phosphorylation outside invadopodia.
Title: A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.
findings show that TGF-beta1 induces RhoC mRNA and protein expression, in parallel with enhanced invasiveness of MM1 cells, a clone derived from rat ascites hepatoma cells [RhoC]
Title: RhoC is essential for TGF-beta1-induced invasive capacity of rat ascites hepatoma cells.
The following Rhoc gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rhoc cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01352 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106461.1 | |
Accession Version | NM_001106461.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | rho-related GTP-binding protein RhoC | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474015.2. On or before Oct 4, 2007 this sequence version replaced XM_215659.4, XM_001068816.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC166849.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGCAA TCCGAAAGAA GCTGGTAATT GTGGGTGATG GCGCCTGCGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001099931.1 |
CDS | 265..846 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106461.1 |
1 | ATGGCCGCAA TCCGAAAGAA GCTGGTAATT GTGGGTGATG GCGCCTGCGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa25134 | |
Clone ID Related Accession (Same CDS sequence) | XM_006233074.1 | |
Accession Version | XM_006233074.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | rho-related GTP-binding protein RhoC isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCACAA TCCGAAAGAA GCTGGTAATT GTGGGTGATG GCGCCTGCGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006233136.1 |
CDS | 239..820 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006233074.1 |
1 | ATGGCCACAA TCCGAAAGAA GCTGGTAATT GTGGGTGATG GCGCCTGCGG GAAGACCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Murine Fam65b forms ring-like structures at the base of stereocilia critical for mechanosensory hair cell function. |
Extra-nuclear activation of progesterone receptor in regulating arterial smooth muscle cell migration. |
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia. |
The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells. |
Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma. |