Lsamp cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Lsamp
Entrez Gene ID	29561
Full Name	limbic system-associated membrane protein
General protein information	Preferred Names limbic system-associated membrane protein Names limbic system-associated membrane protein
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 11 Map Location: 11q21
Summary	immunoglobulin (Ig) superfamily member; may act as a recognition molecule for the formation of neuronal connections [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_017242.1	NP_058938.1	limbic system-associated membrane protein precursor
XM_006248339.3	XP_006248401.1	limbic system-associated membrane protein isoform X1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP002628	XP_312298.5
Pan troglodytes (chimpanzee)	LSAMP	XP_516662.2
Canis lupus familiaris (dog)	LSAMP	XP_005639572.1
Homo sapiens (human)	LSAMP	NP_002329.2
Drosophila melanogaster (fruit fly)	CG34353	NP_001247342.1
Xenopus tropicalis (tropical clawed frog)	lsamp	NP_001096385.1
Rattus norvegicus (Norway rat)	Lsamp	NP_058938.1
Gallus gallus (chicken)	LSAMP	NP_990205.1
Bos taurus (cattle)	LSAMP	NP_001192297.1
Mus musculus (house mouse)	Lsamp	NP_780757.1
Danio rerio (zebrafish)	lsamp	NP_001034921.1

Gene Ontology
Bibliography

Related articles in PubMed

Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons.
Sanz RL, Ferraro GB, Girouard MP, Fournier AE
Scientific reports7(1)7961(2017 Aug)

Genetic deletion of Lsamp causes exaggerated behavioral activation in novel environments.
Catania EH, Pimenta A, Levitt P
Behavioural brain research188(2)380-90(2008 Apr)

Characterization of the genomic structure of the mouse limbic system-associated membrane protein (Lsamp) gene.
Pimenta AF, Levitt P
Genomics83(5)790-801(2004 May)

Rats with low exploratory activity in the elevated plus-maze have the increased expression of limbic system-associated membrane protein gene in the periaqueductal grey.
Nelovkov A, Philips MA, K?ks S, Vasar E
Neuroscience letters352(3)179-82(2003 Dec)

The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting.
Pimenta AF, Zhukareva V, Barbe MF, Reinoso BS, Grimley C, Henzel W, Fischer I, Levitt P
Neuron15(2)287-97(1995 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

It is likely that LSAMP plays a role in the regulation of exploratory behavior of rats in the novel aversive environment.
Title: Rats with low exploratory activity in the elevated plus-maze have the increased expression of limbic system-associated membrane protein gene in the periaqueductal grey.

The following Lsamp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Lsamp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa34275	XM_006248339.3 Latest version!	Rattus norvegicus limbic system-associated membrane protein (Lsamp), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00
ORa03358	NM_017242.1 Latest version!	Rattus norvegicus limbic system-associated membrane protein (Lsamp), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Lsamp ( XM_006248339.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006248401.1 Rattus norvegicus limbic system-associated membrane protein (Lsamp), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa34275
Clone ID Related Accession (Same CDS sequence)	XM_006248339.3
Accession Version	XM_006248339.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1086bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	limbic system-associated membrane protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248339.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTCGGGA GAGTTCAACC TGATCGGAAA CAGTTGCCGC TGGTCCTACT GAGACTGCTC 
TGCCTTCTTC CCACAGGACT GCCCGTTCGC AGCGTGGATT TTAACCGAGG CACGGACAAC 
ATCACCGTGA GGCAGGGGGA CACGGCCATC CTCAGGTGTG TGGTAGAAGA CAAGAACTCG 
AAAGTGGCCT GGTTGAACCG CTCTGGCATC ATCTTCGCTG GACACGACAA GTGGTCTCTG 
GACCCTCGGG TTGAGCTGGA GAAACGCCAT GCTCTGGAAT ACAGCCTCCG AATCCAGAAG 
GTGGATGTCT ATGATGAAGG ATCCTACACA TGCTCAGTTC AGACACAGCA TGAGCCCAAG 
ACCTCTCAAG TTTACTTGAT TGTACAAGTT CCACCAAAGA TCTCCAACAT CTCCTCGGAT 
GTCACTGTGA ATGAGGGCAG CAATGTAACC CTGGTCTGCA TGGCCAATGG GCGCCCTGAA 
CCTGTTATCA CCTGGAGACA CCTTACACCA CTTGGAAGAG AATTTGAAGG AGAAGAAGAA 
TATCTGGAGA TCCTAGGCAT CACCAGGGAA CAGTCAGGCA AATATGAGTG CAAGGCTGCC 
AACGAGGTCT CCTCCGCGGA TGTCAAACAA GTCAAGGTCA CTGTGAACTA TCCACCCACC 
ATCACAGAGT CTAAGAGCAA TGAAGCCACC ACAGGACGAC AAGCTTCCCT CAAATGTGAA 
GCCTCAGCGG TGCCTGCACC TGACTTTGAG TGGTACCGGG ATGACACCAG GATAAACAGT 
GCAAACGGCC TTGAGATTAA GAGCACTGAG GGCCAGTCCT CCCTGACGGT GACCAACGTC 
ACTGAGGAAC ACTACGGCAA CTATACCTGT GTGGCTGCCA ACAAGCTCGG CGTCACCAAT 
GCCAGCCTAG TCCTTTTCAA GCGTGTTTTA CCCACAGTCC CCCACCCTAT TCAAGAAATT 
GGTACCACCG TGCACTTCAA GCAAAAAGGA CCCGGGTCGG TGAGAGGAAT CAACGGATCC 
ATCAGTCTGG CCGTACCACT GTGGCTGCTG GCAGCGTCCC TGTTCTGCCT TCTCAGCAAA 
TGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006248401.1
CDS	507..1592
Translation	MVGRVQPDRKQLPLVLLRLLCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDPRVELEKRHALEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPLGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFKRVLPTVPHPIQEIGTTVHFKQKGPGSVRGINGSISLAVPLWLLAASLFCLLSKC

Target ORF information:

RefSeq Version	XM_006248339.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus limbic system-associated membrane protein (Lsamp), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006248339.3

ORF Insert Sequence:

ATGGTCGGGA GAGTTCAACC TGATCGGAAA CAGTTGCCGC TGGTCCTACT GAGACTGCTC 
TGCCTTCTTC CCACAGGACT GCCCGTTCGC AGCGTGGATT TTAACCGAGG CACGGACAAC 
ATCACCGTGA GGCAGGGGGA CACGGCCATC CTCAGGTGTG TGGTAGAAGA CAAGAACTCG 
AAAGTGGCCT GGTTGAACCG CTCTGGCATC ATCTTCGCTG GACACGACAA GTGGTCTCTG 
GACCCTCGGG TTGAGCTGGA GAAACGCCAT GCTCTGGAAT ACAGCCTCCG AATCCAGAAG 
GTGGATGTCT ATGATGAAGG ATCCTACACA TGCTCAGTTC AGACACAGCA TGAGCCCAAG 
ACCTCTCAAG TTTACTTGAT TGTACAAGTT CCACCAAAGA TCTCCAACAT CTCCTCGGAT 
GTCACTGTGA ATGAGGGCAG CAATGTAACC CTGGTCTGCA TGGCCAATGG GCGCCCTGAA 
CCTGTTATCA CCTGGAGACA CCTTACACCA CTTGGAAGAG AATTTGAAGG AGAAGAAGAA 
TATCTGGAGA TCCTAGGCAT CACCAGGGAA CAGTCAGGCA AATATGAGTG CAAGGCTGCC 
AACGAGGTCT CCTCCGCGGA TGTCAAACAA GTCAAGGTCA CTGTGAACTA TCCACCCACC 
ATCACAGAGT CTAAGAGCAA TGAAGCCACC ACAGGACGAC AAGCTTCCCT CAAATGTGAA 
GCCTCAGCGG TGCCTGCACC TGACTTTGAG TGGTACCGGG ATGACACCAG GATAAACAGT 
GCAAACGGCC TTGAGATTAA GAGCACTGAG GGCCAGTCCT CCCTGACGGT GACCAACGTC 
ACTGAGGAAC ACTACGGCAA CTATACCTGT GTGGCTGCCA ACAAGCTCGG CGTCACCAAT 
GCCAGCCTAG TCCTTTTCAA GCGTGTTTTA CCCACAGTCC CCCACCCTAT TCAAGAAATT 
GGTACCACCG TGCACTTCAA GCAAAAAGGA CCCGGGTCGG TGAGAGGAAT CAACGGATCC 
ATCAGTCTGG CCGTACCACT GTGGCTGCTG GCAGCGTCCC TGTTCTGCCT TCTCAGCAAA 
TGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Lsamp ( NM_017242.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_058938.1 Rattus norvegicus limbic system-associated membrane protein (Lsamp), mRNA.

Price & Availability↑

CloneID	ORa03358
Clone ID Related Accession (Same CDS sequence)	NM_017242.1
Accession Version	NM_017242.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1017bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	limbic system-associated membrane protein precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U31554.1. Sequence Note: This sequence has been modified as follows: removed 20 bp suspected to be vector contamination from the 3' end. ##Evidence-Data-START## Transcript exon combination :: U31554.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGTCGGGA GAGTTCAACC TGATCGGAAA CAGTTGCCAC TGGTCCTACT GAGACTGCTC 
TGCCTTCTTC CCACAGGACT GCCCGTTCGC AGCGTGGATT TTAACCGAGG CACGGACAAC 
ATCACCGTGA GGCAGGGGGA CACGGCCATC CTCAGGTGTG TGGTAGAAGA CAAGAACTCG 
AAAGTGGCCT GGTTGAACCG CTCTGGCATC ATCTTCGCTG GACACGACAA GTGGTCTCTG 
GACCCTCGGG TTGAGCTGGA GAAACGCCAT GCTCTGGAAT ACAGCCTCCG AATCCAGAAG 
GTGGATGTCT ATGATGAAGG ATCCTACACA TGCTCAGTTC AGACACAGCA TGAGCCCAAG 
ACCTCTCAAG TTTACTTGAT TGTACAAGTT CCACCAAAGA TCTCCAACAT CTCCTCGGAT 
GTCACTGTGA ATGAGGGCAG CAATGTAACC CTGGTCTGCA TGGCCAATGG GCGCCCTGAA 
CCTGTTATCA CCTGGAGACA CCTTACACCA CTTGGAAGAG AATTTGAAGG AGAAGAAGAA 
TATCTGGAGA TCCTAGGCAT CACCAGGGAA CAGTCAGGCA AATATGAGTG CAAGGCTGCC 
AACGAGGTCT CCTCCGCGGA TGTCAAACAA GTCAAGGTCA CTGTGAACTA TCCACCCACC 
ATCACAGAGT CTAAGAGCAA TGAAGCCACC ACAGGACGAC AAGCTTCCCT CAAATGTGAA 
GCCTCAGCGG TGCCTGCACC TGACTTTGAG TGGTACCGGG ATGACACCAG GATAAACAGT 
GCAAACGGCC TTGAGATTAA GAGCACTGAG GGCCAGTCCT CCCTGACGGT GACCAACGTC 
ACTGAGGAAC ACTACGGCAA CTATACCTGT GTGGCTGCCA ACAAGCTCGG CGTCACCAAT 
GCCAGCCTAG TCCTTTTCAG ACCCGGGTCG GTGAGAGGAA TCAACGGATC CATCAGTCTG 
GCCGTACCAC TGTGGCTGCT GGCAGCGTCC CTGTTCTGCC TTCTCAGCAA ATGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_058938.1
CDS	56..1072
Translation	MVGRVQPDRKQLPLVLLRLLCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDPRVELEKRHALEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPLGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFRPGSVRGINGSISLAVPLWLLAASLFCLLSKC

Target ORF information:

RefSeq Version	NM_017242.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus limbic system-associated membrane protein (Lsamp), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017242.1

ORF Insert Sequence:

ATGGTCGGGA GAGTTCAACC TGATCGGAAA CAGTTGCCAC TGGTCCTACT GAGACTGCTC 
TGCCTTCTTC CCACAGGACT GCCCGTTCGC AGCGTGGATT TTAACCGAGG CACGGACAAC 
ATCACCGTGA GGCAGGGGGA CACGGCCATC CTCAGGTGTG TGGTAGAAGA CAAGAACTCG 
AAAGTGGCCT GGTTGAACCG CTCTGGCATC ATCTTCGCTG GACACGACAA GTGGTCTCTG 
GACCCTCGGG TTGAGCTGGA GAAACGCCAT GCTCTGGAAT ACAGCCTCCG AATCCAGAAG 
GTGGATGTCT ATGATGAAGG ATCCTACACA TGCTCAGTTC AGACACAGCA TGAGCCCAAG 
ACCTCTCAAG TTTACTTGAT TGTACAAGTT CCACCAAAGA TCTCCAACAT CTCCTCGGAT 
GTCACTGTGA ATGAGGGCAG CAATGTAACC CTGGTCTGCA TGGCCAATGG GCGCCCTGAA 
CCTGTTATCA CCTGGAGACA CCTTACACCA CTTGGAAGAG AATTTGAAGG AGAAGAAGAA 
TATCTGGAGA TCCTAGGCAT CACCAGGGAA CAGTCAGGCA AATATGAGTG CAAGGCTGCC 
AACGAGGTCT CCTCCGCGGA TGTCAAACAA GTCAAGGTCA CTGTGAACTA TCCACCCACC 
ATCACAGAGT CTAAGAGCAA TGAAGCCACC ACAGGACGAC AAGCTTCCCT CAAATGTGAA 
GCCTCAGCGG TGCCTGCACC TGACTTTGAG TGGTACCGGG ATGACACCAG GATAAACAGT 
GCAAACGGCC TTGAGATTAA GAGCACTGAG GGCCAGTCCT CCCTGACGGT GACCAACGTC 
ACTGAGGAAC ACTACGGCAA CTATACCTGT GTGGCTGCCA ACAAGCTCGG CGTCACCAAT 
GCCAGCCTAG TCCTTTTCAG ACCCGGGTCG GTGAGAGGAA TCAACGGATC CATCAGTCTG 
GCCGTACCAC TGTGGCTGCT GGCAGCGTCC CTGTTCTGCC TTCTCAGCAA ATGTTAA