Gene Symbol | Rag2 |
Entrez Gene ID | 295953 |
Full Name | recombination activating 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Rag2 cDNA ORF clone
Gene Symbol | Rag2 |
Entrez Gene ID | 295953 |
Full Name | recombination activating 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001100528.1 | NP_001093998.1 | V(D)J recombination-activating protein 2 |
Canis lupus familiaris (dog) | RAG2 | XP_005631162.1 |
RAG2 | XP_001114734.2 | |
Bos taurus (cattle) | RAG2 | NP_001075938.1 |
Rattus norvegicus (Norway rat) | Rag2 | NP_001093998.1 |
Gallus gallus (chicken) | RAG2 | XP_004941607.1 |
Homo sapiens (human) | RAG2 | NP_001230714.1 |
Mus musculus (house mouse) | Rag2 | NP_033046.1 |
Xenopus tropicalis (tropical clawed frog) | rag2 | XP_002937337.2 |
Pan troglodytes (chimpanzee) | RAG2 | XP_521889.1 |
Danio rerio (zebrafish) | rag2 | NP_571460.2 |
Readout of epigenetic modifications.
Patel DJ, Wang Z
Annual review of biochemistry8281-118(2013)
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.
Hewitt SL, Yin B, Ji Y, Chaumeil J, Marszalek K, Tenthorey J, Salvagiotto G, Steinel N, Ramsey LB, Ghysdael J, Farrar MA, Sleckman BP, Schatz DG, Busslinger M, Bassing CH, Skok JA
Nature immunology10(6)655-64(2009 Jun)
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.
Matthews AG, Kuo AJ, Ram?n-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA
Nature450(7172)1106-10(2007 Dec)
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.
Ram?n-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W
Proceedings of the National Academy of Sciences of the United States of America104(48)18993-8(2007 Nov)
A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
Elkin SK, Ivanov D, Ewalt M, Ferguson CG, Hyberts SG, Sun ZY, Prestwich GD, Yuan J, Wagner G, Oettinger MA, Gozani OP
The Journal of biological chemistry280(31)28701-10(2005 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Rag2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rag2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01444 | |
Clone ID Related Accession (Same CDS sequence) | NM_001100528.1 | |
Accession Version | NM_001100528.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | V(D)J recombination-activating protein 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Dec 12, 2009 this sequence version replaced XM_230374.4, XM_001079235.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689605, SAMN01906349 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTCCCTGC AGATGGTTAC AGTGGGTCAT AACATAGCCT TAATTCAACC AGGCTTCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001093998.1 |
CDS | 217..1800 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001100528.1 |
1 | ATGTCCCTGC AGATGGTTAC AGTGGGTCAT AACATAGCCT TAATTCAACC AGGCTTCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Readout of epigenetic modifications. |
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. |
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination. |
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2. |
A PHD finger motif in the C terminus of RAG2 modulates recombination activity. |