| Gene Symbol | Usp8 |
| Entrez Gene ID | 296121 |
| Full Name | ubiquitin specific peptidase 8 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Usp8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Usp8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa26320 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006234916.3 , XM_008762155.2 , NM_001106502.1 | |
| Accession Version | NM_001106502.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-21 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | ubiquitin carboxyl-terminal hydrolase 8 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_215821.4, XM_001078286.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. | |
1 | ATGCCTGCTG TAGCTTCAGT TCCTAAAGAA CTCTACCTCA GTTCTTCACT CAAAGACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001099972.1 |
| CDS | 155..3400 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001106502.1 |
1 | ATGCCTGCTG TAGCTTCAGT TCCTAAAGAA CTCTACCTCA GTTCTTCACT CAAAGACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa26320 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006234916.3 , XM_008762155.2 , NM_001106502.1 | |
| Accession Version | XM_006234916.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | ubiquitin carboxyl-terminal hydrolase 8 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234916.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTGCTG TAGCTTCAGT TCCTAAAGAA CTCTACCTCA GTTCTTCACT CAAAGACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006234978.1 |
| CDS | 201..3446 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006234916.3 |
1 | ATGCCTGCTG TAGCTTCAGT TCCTAAAGAA CTCTACCTCA GTTCTTCACT CAAAGACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa26320 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006234916.3 , XM_008762155.2 , NM_001106502.1 | |
| Accession Version | XM_008762155.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | ubiquitin carboxyl-terminal hydrolase 8 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008762155.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTGCTG TAGCTTCAGT TCCTAAAGAA CTCTACCTCA GTTCTTCACT CAAAGACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008760377.1 |
| CDS | 201..3446 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008762155.2 |
1 | ATGCCTGCTG TAGCTTCAGT TCCTAAAGAA CTCTACCTCA GTTCTTCACT CAAAGACCTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation. |
The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. |
The deubiquitinating enzyme UBPy/USP8 interacts with TrkA and inhibits neuronal differentiation in PC12 cells. |
Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8. |
