Prpf4 cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Prpf4 |
| Entrez Gene ID | 298095 |
| Full Name | pre-mRNA processing factor 4 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001106659.1 | NP_001100129.1 | U4/U6 small nuclear ribonucleoprotein Prp4 |
| Homo sapiens (human) | PRPF4 | NP_001231855.1 |
| Danio rerio (zebrafish) | prpf4 | NP_956049.1 |
| Danio rerio (zebrafish) | LOC100334455 | XP_002662201.1 |
| Caenorhabditis elegans (roundworm) | prp-4 | NP_492363.1 |
| Kluyveromyces lactis | KLLA0E04819g | XP_454163.1 |
| Neurospora crassa | NCU11251 | XP_001728376.1 |
| Canis lupus familiaris (dog) | PRPF4 | XP_532038.2 |
| Drosophila melanogaster (fruit fly) | U4-U6-60K | NP_648990.1 |
| Eremothecium gossypii | AGOS_AEL269C | NP_984591.1 |
| Schizosaccharomyces pombe (fission yeast) | SPAC227.12 | NP_592966.1 |
| Arabidopsis thaliana (thale cress) | AT2G05720 | NP_178635.1 |
| Rattus norvegicus (Norway rat) | Prpf4 | NP_001100129.1 |
| Arabidopsis thaliana (thale cress) | LIS | NP_181681.1 |
| PRPF4 | XP_001102859.1 | |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002144 | XP_308051.4 |
| Magnaporthe oryzae (rice blast fungus) | MGG_01259 | XP_003714171.1 |
| Xenopus tropicalis (tropical clawed frog) | prpf4 | NP_989058.1 |
| Pan troglodytes (chimpanzee) | PRPF4 | XP_520198.3 |
| Bos taurus (cattle) | PRPF4 | NP_001029502.1 |
| Mus musculus (house mouse) | Prpf4 | NP_081573.1 |
| Gallus gallus (chicken) | PRPF4 | XP_415544.3 |
| Saccharomyces cerevisiae (baker's yeast) | PRP4 | NP_015504.1 |
Related articles in PubMed
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will CL, Urlaub H, Kastner B, L?hrmann R, Stark H
Cell170(4)701-713.e11(2017 Aug)
Identification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosa.
Linder B, Hirmer A, Gal A, R?ther K, Bolz HJ, Winkler C, Laggerbauer B, Fischer U
PloS one9(11)e111754(2014)
The nuclear cap-binding complex interacts with the U4/U6?U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.
Pabis M, Neufeld N, Steiner MC, Bojic T, Shav-Tal Y, Neugebauer KM
RNA (New York, N.Y.)19(8)1054-63(2013 Aug)
The spliceosome: design principles of a dynamic RNP machine.
Wahl MC, Will CL, L?hrmann R
Cell136(4)701-18(2009 Feb)
RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies.
Schaffert N, Hossbach M, Heintzmann R, Achsel T, L?hrmann R
The EMBO journal23(15)3000-9(2004 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Prpf4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Prpf4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01911 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001106659.1 | |
| Accession Version | NM_001106659.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1566bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-18 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | U4/U6 small nuclear ribonucleoprotein Prp4 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473978.2. On or before Oct 4, 2007 this sequence version replaced XM_233022.4, XM_001057634.1. ##Evidence-Data-START## Transcript exon combination :: BC168915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTCCT CACGAGCCTC CTCCACGACA ACCAAAACTA AAGCACCTGA CGATTTAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001100129.1 |
| CDS | 76..1641 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001106659.1 |
ORF Insert Sequence:
1 | ATGGCCTCCT CACGAGCCTC CTCCACGACA ACCAAAACTA AAGCACCTGA CGATTTAGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. |
|
Identification of a PRPF4 loss-of-function variant that abrogates U4/U6.U5 tri-snRNP integration and is associated with retinitis pigmentosa. |
|
The nuclear cap-binding complex interacts with the U4/U6?U5 tri-snRNP and promotes spliceosome assembly in mammalian cells. |
|
The spliceosome: design principles of a dynamic RNP machine. |
|
RNAi knockdown of hPrp31 leads to an accumulation of U4/U6 di-snRNPs in Cajal bodies. |