Gene Symbol | Arhgap8 |
Entrez Gene ID | 300115 |
Full Name | Rho GTPase activating protein 8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Arhgap8 cDNA ORF clone
gRNAs
Gene Symbol | Arhgap8 |
Entrez Gene ID | 300115 |
Full Name | Rho GTPase activating protein 8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017594773.1 | XP_017450262.1 | rho GTPase-activating protein 8 isoform X1 |
NM_001004242.1 | NP_001004242.1 | rho GTPase-activating protein 8 |
XM_017594772.1 | XP_017450261.1 | rho GTPase-activating protein 8 isoform X1 |
Homo sapiens (human) | ARHGAP8 | NP_851852.2 |
Canis lupus familiaris (dog) | ARHGAP8 | NP_001191334.1 |
Mus musculus (house mouse) | Arhgap8 | NP_082731.2 |
Gallus gallus (chicken) | ARHGAP8 | NP_001191318.1 |
Pan troglodytes (chimpanzee) | ARHGAP8 | XP_003317351.1 |
Homo sapiens (human) | PRR5-ARHGAP8 | NP_851851.2 |
Rattus norvegicus (Norway rat) | Arhgap8 | NP_001004242.1 |
Xenopus tropicalis (tropical clawed frog) | arhgap8 | NP_001016951.1 |
SmgGDS antagonizes BPGAP1-induced Ras/ERK activation and neuritogenesis in PC12 cell differentiation.
Ravichandran A, Low BC
Molecular biology of the cell24(2)145-56(2013 Jan)
Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration.
Pan CQ, Liou YC, Low BC
Journal of cell science123(Pt 6)903-16(2010 Mar)
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes.
Wang L, Yang L, Debidda M, Witte D, Zheng Y
Proceedings of the National Academy of Sciences of the United States of America104(4)1248-53(2007 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Unique role of BPGAP1 as a dual regulator for Ras and Rho signaling in cell morphogenesis and differentiation.
Title: SmgGDS antagonizes BPGAP1-induced Ras/ERK activation and neuritogenesis in PC12 cell differentiation.
The following Arhgap8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Arhgap8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10206 | |
Clone ID Related Accession (Same CDS sequence) | XM_017594773.1 , NM_001004242.1 , XM_017594772.1 | |
Accession Version | NM_001004242.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | rho GTPase-activating protein 8 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079089.1. On Sep 10, 2004 this sequence version replaced XM_217004.2. ##Evidence-Data-START## Transcript exon combination :: BC079089.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN02642770, SAMN02642786 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTGGCC TGGACCCCAC GCTGAGCACA AGTCACCCAT TCTATGATGT GGCCAGACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001004242.1 |
CDS | 116..1393 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTGGCC TGGACCCCAC GCTGAGCACA AGTCACCCAT TCTATGATGT GGCCAGACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa10206 | |
Clone ID Related Accession (Same CDS sequence) | XM_017594773.1 , NM_001004242.1 , XM_017594772.1 | |
Accession Version | XM_017594773.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | rho GTPase-activating protein 8 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGGCC TGGACCCCAC GCTGAGCACA AGTCACCCAT TCTATGATGT GGCCAGACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017450262.1 |
CDS | 145..1422 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTGGCC TGGACCCCAC GCTGAGCACA AGTCACCCAT TCTATGATGT GGCCAGACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa10206 | |
Clone ID Related Accession (Same CDS sequence) | XM_017594773.1 , NM_001004242.1 , XM_017594772.1 | |
Accession Version | XM_017594772.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1278bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | rho GTPase-activating protein 8 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGGCC TGGACCCCAC GCTGAGCACA AGTCACCCAT TCTATGATGT GGCCAGACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017450261.1 |
CDS | 130..1407 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTGGCC TGGACCCCAC GCTGAGCACA AGTCACCCAT TCTATGATGT GGCCAGACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
SmgGDS antagonizes BPGAP1-induced Ras/ERK activation and neuritogenesis in PC12 cell differentiation. |
Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration. |
Cdc42 GTPase-activating protein deficiency promotes genomic instability and premature aging-like phenotypes. |