| Gene Symbol | Efhc1 |
| Entrez Gene ID | 301295 |
| Full Name | EF-hand domain containing 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Efhc1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Efhc1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa01243 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001122947.2 | |
| Accession Version | NM_001122947.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1947bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-02-04 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | EF-hand domain-containing protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07067033.1. On Jul 22, 2009 this sequence version replaced NM_001122947.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGTGACCA ACCCGGTGCA CGGCCTGCCC TTACTCCCGG GCTCGTCCTT TACGGACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001116419.2 |
| CDS | 47..1993 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001122947.2 |
1 | ATGGTGACCA ACCCGGTGCA CGGCCTGCCC TTACTCCCGG GCTCGTCCTT TACGGACTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Microtubule-associated defects caused by EFHC1 mutations in juvenile myoclonic epilepsy. |
Mutations of EFHC1, linked to juvenile myoclonic epilepsy, disrupt radial and tangential migrations during brain development. |
EFHC1 interacts with microtubules to regulate cell division and cortical development. |
Expression profile and distribution of Efhc1 gene transcript during rodent brain development. |
The mouse ortholog of EFHC1 implicated in juvenile myoclonic epilepsy is an axonemal protein widely conserved among organisms with motile cilia and flagella. |
