Gene Symbol | Maml1 |
Entrez Gene ID | 303101 |
Full Name | mastermind-like transcriptional coactivator 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Maml1 cDNA ORF clone
Gene Symbol | Maml1 |
Entrez Gene ID | 303101 |
Full Name | mastermind-like transcriptional coactivator 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006246251.2 | XP_006246313.1 | mastermind-like protein 1 isoform X1 |
NM_001106997.1 | NP_001100467.1 | mastermind-like protein 1 |
Rattus norvegicus (Norway rat) | Maml1 | NP_001100467.1 |
Homo sapiens (human) | MAML1 | NP_055572.1 |
MAML1 | XP_001105097.2 | |
Bos taurus (cattle) | MAML1 | XP_005208449.1 |
Gallus gallus (chicken) | MAML1 | XP_414607.4 |
Mus musculus (house mouse) | Maml1 | NP_780543.2 |
Danio rerio (zebrafish) | LOC567335 | XP_005157273.1 |
Pan troglodytes (chimpanzee) | MAML1 | XP_527150.3 |
Canis lupus familiaris (dog) | MAML1 | XP_005626406.1 |
Xenopus tropicalis (tropical clawed frog) | maml1 | XP_002941844.2 |
Notch pathway is activated in cell culture and mouse models of mutant SOD1-related familial amyotrophic lateral sclerosis, with suppression of its activation as an additional mechanism of neuroprotection for lithium and valproate.
Wang SY, Ren M, Jiang HZ, Wang J, Jiang HQ, Yin X, Qi Y, Wang XD, Dong GT, Wang TH, Yang YQ, Feng HL
Neuroscience301276-88(2015 Aug)
BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets.
Tiberi L, van den Ameele J, Dimidschstein J, Piccirilli J, Gall D, Herpoel A, Bilheu A, Bonnefont J, Iacovino M, Kyba M, Bouschet T, Vanderhaeghen P
Nature neuroscience15(12)1627-35(2012 Dec)
Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways.
Rentschler S, Harris BS, Kuznekoff L, Jain R, Manderfield L, Lu MM, Morley GE, Patel VV, Epstein JA
The Journal of clinical investigation121(2)525-33(2011 Feb)
Cell and molecular biology of Notch.
Fi?za UM, Arias AM
The Journal of endocrinology194(3)459-74(2007 Sep)
The notch regulator MAML1 interacts with p53 and functions as a coactivator.
Zhao Y, Katzman RB, Delmolino LM, Bhat I, Zhang Y, Gurumurthy CB, Germaniuk-Kurowska A, Reddi HV, Solomon A, Zeng MS, Kung A, Ma H, Gao Q, Dimri G, Stanculescu A, Miele L, Wu L, Griffin JD, Wazer DE, Band H, Band V
The Journal of biological chemistry282(16)11969-81(2007 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Maml1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Maml1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa05081 | |
Clone ID Related Accession (Same CDS sequence) | NM_001106997.1 | |
Accession Version | NM_001106997.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2355bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | mastermind-like protein 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 4, 2007 this sequence version replaced XM_220373.4, XM_001071703.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGATCGCAG GGGCTGGCAG CTCTGTAGCT CAGAGCAACC TCATGCCTGA CCTCAACCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001100467.1 |
CDS | 956..3310 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001106997.1 |
1 | ATGATCGCAG GGGCTGGCAG CTCTGTAGCT CAGAGCAACC TCATGCCTGA CCTCAACCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa33033 | |
Clone ID Related Accession (Same CDS sequence) | XM_006246251.2 | |
Accession Version | XM_006246251.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3054bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | mastermind-like protein 1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006246251.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006246313.1 |
CDS | 1531..4584 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006246251.2 |
1 | ATGGTGCTAC CCACCTGCCC CATGGCGGAG TTCGCGCTGC CGCGGCACAG CGCGGTCATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Notch pathway is activated in cell culture and mouse models of mutant SOD1-related familial amyotrophic lateral sclerosis, with suppression of its activation as an additional mechanism of neuroprotection for lithium and valproate. |
BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets. |
Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways. |
Cell and molecular biology of Notch. |
The notch regulator MAML1 interacts with p53 and functions as a coactivator. |