Gene Symbol | Pds5b |
Entrez Gene ID | 304218 |
Full Name | PDS5 cohesin associated factor B |
Synonyms | AS3,Aprin,CG008 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Pds5b cDNA ORF clone
Gene Symbol | Pds5b |
Entrez Gene ID | 304218 |
Full Name | PDS5 cohesin associated factor B |
Synonyms | AS3,Aprin,CG008 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001102383.2 | NP_001095853.1 | sister chromatid cohesion protein PDS5 homolog B isoform 1 |
XM_017598314.1 | XP_017453803.1 | sister chromatid cohesion protein PDS5 homolog B isoform X3 |
XM_017598313.1 | XP_017453802.1 | sister chromatid cohesion protein PDS5 homolog B isoform X2 |
NM_001101805.1 | NP_001095275.1 | sister chromatid cohesion protein PDS5 homolog B isoform 2 |
XM_008768957.2 | XP_008767179.1 | sister chromatid cohesion protein PDS5 homolog B isoform X1 |
PDS5B | XP_001118201.2 | |
Bos taurus (cattle) | PDS5B | XP_002691801.2 |
Caenorhabditis elegans (roundworm) | evl-14 | NP_497865.2 |
Saccharomyces cerevisiae (baker's yeast) | PDS5 | NP_013793.1 |
Kluyveromyces lactis | KLLA0F25806g | XP_456229.1 |
Schizosaccharomyces pombe (fission yeast) | pds5 | NP_593535.1 |
Neurospora crassa | NCU00424 | XP_956688.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_06465 | XP_003717099.1 |
Homo sapiens (human) | PDS5B | NP_055847.1 |
Danio rerio (zebrafish) | pds5b | XP_693953.2 |
Drosophila melanogaster (fruit fly) | pds5 | NP_001246271.1 |
Canis lupus familiaris (dog) | PDS5B | XP_543139.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010643 | XP_311361.4 |
Eremothecium gossypii | AGOS_AGL076W | NP_986590.1 |
Xenopus tropicalis (tropical clawed frog) | pds5b | NP_001107500.1 |
Pan troglodytes (chimpanzee) | PDS5B | XP_003314158.2 |
Mus musculus (house mouse) | Pds5b | NP_780519.3 |
Rattus norvegicus (Norway rat) | Pds5b | NP_001095853.1 |
Gallus gallus (chicken) | PDS5B | NP_001012845.2 |
Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.
Zhang B, Chang J, Fu M, Huang J, Kashyap R, Salavaggione E, Jain S, Kulkarni S, Shashikant K, Deardorff MA, Uzielli ML, Dorsett D, Beebe DC, Jay PY, Heuckeroth RO, Krantz I, Milbrandt J
PloS one4(5)e5232(2009)
Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.
Watrin E, Schleiffer A, Tanaka K, Eisenhaber F, Nasmyth K, Peters JM
Current biology : CB16(9)863-74(2006 May)
Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.
Losada A, Yokochi T, Hirano T
Journal of cell science118(Pt 10)2133-41(2005 May)
Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator.
Geck P, Maffini MV, Szelei J, Sonnenschein C, Soto AM
Proceedings of the National Academy of Sciences of the United States of America97(18)10185-90(2000 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
AS3 is a mediator of the proliferative arrest in the normal rat prostate in situ and that its expression is androgen-induced (AS3 protein)
Title: Mechanism of androgen action on cell proliferation: AS3 protein as a mediator of proliferative arrest in the rat prostate.
The following Pds5b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pds5b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa57805 | |
Clone ID Related Accession (Same CDS sequence) | XM_017598313.1 | |
Accession Version | XM_017598313.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2970bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sister chromatid cohesion protein PDS5 homolog B isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017453802.1 |
CDS | 20..2989 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017598313.1 |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa57806 | |
Clone ID Related Accession (Same CDS sequence) | XM_017598314.1 | |
Accession Version | XM_017598314.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4344bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sister chromatid cohesion protein PDS5 homolog B isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017453803.1 |
CDS | 20..4363 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017598314.1 |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa46122 | |
Clone ID Related Accession (Same CDS sequence) | XM_008768957.2 | |
Accession Version | XM_008768957.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3576bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sister chromatid cohesion protein PDS5 homolog B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008768957.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008767179.1 |
CDS | 112..3687 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008768957.2 |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa00551 | |
Clone ID Related Accession (Same CDS sequence) | NM_001101805.1 | |
Accession Version | NM_001101805.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4242bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sister chromatid cohesion protein PDS5 homolog B isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07034927.1, CK357543.1 and AABR07034928.1. On or before Aug 22, 2007 this sequence version replaced XM_221833.4, XM_001056510.1, XM_001056563.1. Transcript Variant: This variant (2) lacks alternate in-frame segments in the 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001095275.1 |
CDS | 10..4251 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001101805.1 |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa00568 | |
Clone ID Related Accession (Same CDS sequence) | NM_001102383.2 | |
Accession Version | NM_001102383.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4353bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sister chromatid cohesion protein PDS5 homolog B isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07034927.1, CK357543.1 and AABR07034928.1. On Dec 28, 2007 this sequence version replaced NM_001102383.1. Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001095853.1 |
CDS | 10..4362 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001102383.2 |
1 | ATGGCTCATT CAAAGACAAG AACCAACGAT GGCAAAATTA CTTACCCTCC TGGTGTCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies. |
Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression. |
Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts. |
Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator. |