Abhd6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Abhd6
Entrez Gene ID	305795
Full Name	abhydrolase domain containing 6
General protein information	Preferred Names abhydrolase domain containing 6 Names monoacylglycerol lipase ABHD6 2-arachidonoylglycerol hydrolase abhydrolase domain-containing protein 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 15 Map Location: 15p14

mRNA and Protein(s)

mRNA	Protein	Name
XM_006251768.3	XP_006251830.1	monoacylglycerol lipase ABHD6 isoform X1
XM_006251767.3	XP_006251829.1	monoacylglycerol lipase ABHD6 isoform X1
NM_001007680.1	NP_001007681.1	monoacylglycerol lipase ABHD6
XM_006251766.3	XP_006251828.1	monoacylglycerol lipase ABHD6 isoform X1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ABHD6	XP_001174068.1
Canis lupus familiaris (dog)	ABHD6	XP_541828.1
Rattus norvegicus (Norway rat)	Abhd6	NP_001007681.1
Mus musculus (house mouse)	Abhd6	NP_079617.2
Gallus gallus (chicken)	ABHD6	XP_414352.1
Danio rerio (zebrafish)	abhd6a	XP_001339480.1
Homo sapiens (human)	ABHD6	NP_065727.4
	ABHD6	XP_001096766.1
Bos taurus (cattle)	ABHD6	NP_001068664.1
Xenopus tropicalis (tropical clawed frog)	abhd6	NP_001120619.1

Gene Ontology
Bibliography

Related articles in PubMed

?/?-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes.
Zhao S, Mugabo Y, Ballentine G, Attane C, Iglesias J, Poursharifi P, Zhang D, Nguyen TA, Erb H, Prentki R, Peyot ML, Joly E, Tobin S, Fulton S, Brown JM, Madiraju SR, Prentki M
Cell reports14(12)2872-88(2016 Mar)

?/? Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.
Pribasnig MA, Mrak I, Grabner GF, Taschler U, Knittelfelder O, Scherz B, Eichmann TO, Heier C, Grumet L, Kowaliuk J, Romauch M, Holler S, Anderl F, Wolinski H, Lass A, Breinbauer R, Marsche G, Brown JM, Zimmermann R
The Journal of biological chemistry290(50)29869-81(2015 Dec)

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.
Thomas G, Betters JL, Lord CC, Brown AL, Marshall S, Ferguson D, Sawyer J, Davis MA, Melchior JT, Blume LC, Howlett AC, Ivanova PT, Milne SB, Myers DS, Mrak I, Leber V, Heier C, Taschler U, Blankman JL, Cravatt BF, Lee RG, Crooke RM, Graham MJ, Zimmermann R, Brown HA, Brown JM
Cell reports5(2)508-20(2013 Oct)

Biochemical and pharmacological characterization of human ?/?-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).
Navia-Paldanius D, Savinainen JR, Laitinen JT
Journal of lipid research53(11)2413-24(2012 Nov)

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.
Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, M?ller CS, Bildl W, Baehrens D, H?ber B, Kulik A, Kl?cker N, Schulte U, Fakler B
Neuron74(4)621-33(2012 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Abhd6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Abhd6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa11578	NM_001007680.1 Latest version!	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa11578	XM_006251766.3 Latest version!	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa11578	XM_006251768.3 Latest version!	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00
ORa11578	XM_006251767.3 Latest version!	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$188.30 $269.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Abhd6 ( NM_001007680.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001007681.1 Rattus norvegicus abhydrolase domain containing 6 (Abhd6), mRNA.

Price & Availability↑

CloneID	ORa11578
Clone ID Related Accession (Same CDS sequence)	XM_006251768.3 , XM_006251767.3 , NM_001007680.1 , XM_006251766.3
Accession Version	NM_001007680.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Rattus norvegicus(Norway rat)
Product	monoacylglycerol lipase ABHD6
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083826.1. On Nov 29, 2004 this sequence version replaced XM_223871.2. ##Evidence-Data-START## Transcript exon combination :: BC083826.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001007681.1
CDS	72..1085
Translation	MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNRFVQRLKELEDSAATQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSITNSQVEVLENCGHSVVMERPRKTAKLVVDFLASVHNPDNNKKLN

Target ORF information:

RefSeq Version	NM_001007680.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001007680.1

ORF Insert Sequence:

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abhd6 ( XM_006251768.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251830.1 Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa11578
Clone ID Related Accession (Same CDS sequence)	XM_006251768.3 , XM_006251767.3 , NM_001007680.1 , XM_006251766.3
Accession Version	XM_006251768.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	monoacylglycerol lipase ABHD6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251768.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251830.1
CDS	49..1062
Translation	MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNRFVQRLKELEDSAATQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSITNSQVEVLENCGHSVVMERPRKTAKLVVDFLASVHNPDNNKKLN

Target ORF information:

RefSeq Version	XM_006251768.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251768.3

ORF Insert Sequence:

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abhd6 ( XM_006251767.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251829.1 Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa11578
Clone ID Related Accession (Same CDS sequence)	XM_006251768.3 , XM_006251767.3 , NM_001007680.1 , XM_006251766.3
Accession Version	XM_006251767.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	monoacylglycerol lipase ABHD6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251767.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251829.1
CDS	883..1896
Translation	MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNRFVQRLKELEDSAATQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSITNSQVEVLENCGHSVVMERPRKTAKLVVDFLASVHNPDNNKKLN

Target ORF information:

RefSeq Version	XM_006251767.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251767.3

ORF Insert Sequence:

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Abhd6 ( XM_006251766.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006251828.1 Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa11578
Clone ID Related Accession (Same CDS sequence)	XM_006251768.3 , XM_006251767.3 , NM_001007680.1 , XM_006251766.3
Accession Version	XM_006251766.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1014bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	monoacylglycerol lipase ABHD6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251766.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006251828.1
CDS	1352..2365
Translation	MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQFCYSFRGRPGHKPSVLMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLSIVGQVKRIHQFVECLKLNKKPFHLIGTSMGGNVAGVYAAYYPSDVCSLSLVCPAGLQYSTDNRFVQRLKELEDSAATQKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHNSFYRKLFLEIVSEKSRYSLHENMDKIKVPTQIIWGKQDQVLDVSGADILAKSITNSQVEVLENCGHSVVMERPRKTAKLVVDFLASVHNPDNNKKLN

Target ORF information:

RefSeq Version	XM_006251766.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus abhydrolase domain containing 6 (Abhd6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006251766.3

ORF Insert Sequence:

ATGGATCTCG ATGTGGTTAA CATGTTTGTG ATTGCGGGTG GGACCCTGGC CATTCCGATC 
CTGGCCTTCG TAGCTTCTTT CCTCCTTTGG CCCTCGGCGC TGATAAGAAT CTATTATTGG 
TACTGGCGGA GGACGCTGGG CATGCAAGTC CGCTACGTGC ACCACGAGGA CTATCAGTTC 
TGTTACTCCT TCCGGGGCAG GCCAGGACAC AAGCCGTCCG TCCTTATGCT TCACGGGTTC 
TCCGCACACA AGGATATGTG GCTCAGTGTG GTCAAGTTCC TTCCCAAGAA TCTGCACTTG 
GTCTGTGTGG ACATGCCTGG ACATGAAGGG ACCACCCGTT CCTCCCTGGA TGACCTGTCC 
ATAGTTGGGC AAGTGAAAAG GATACATCAG TTTGTAGAAT GCCTTAAGCT GAACAAAAAG 
CCCTTTCACC TTATAGGCAC CTCCATGGGT GGCAACGTGG CTGGAGTATA CGCTGCTTAC 
TATCCATCTG ACGTCTGCAG CCTGTCTCTC GTGTGCCCTG CTGGCCTGCA GTATTCAACT 
GACAATCGGT TTGTACAACG GCTCAAAGAG CTGGAGGACT CAGCCGCCAC GCAGAAGATC 
CCTTTGATCC CATCCACCCC GGAAGAGATG AGCGAGATGC TGCAGCTCTG CTCGTACGTC 
CGCTTCAAGG TGCCCCAGCA GATCCTTCAA GGTCTTGTCG ACGTTCGCAT CCCTCACAAC 
AGCTTCTACC GGAAATTGTT TTTGGAAATC GTCAGTGAGA AATCCAGATA CTCTCTGCAT 
GAGAACATGG ACAAGATCAA GGTCCCAACA CAGATCATTT GGGGAAAACA AGACCAGGTG 
CTTGATGTGT CGGGGGCAGA CATATTAGCC AAGTCCATCA CTAACTCCCA GGTAGAGGTT 
CTGGAAAACT GTGGCCATTC AGTGGTGATG GAGAGACCGA GGAAGACAGC CAAGCTCGTC 
GTCGACTTTT TAGCTTCTGT GCACAACCCA GACAACAACA AGAAGCTGAA CTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

?/?-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes.
Cell reports14(12)2872-88(2016 Mar)
Zhao S,Mugabo Y,Ballentine G,Attane C,Iglesias J,Poursharifi P,Zhang D,Nguyen TA,Erb H,Prentki R,Peyot ML,Joly E,Tobin S,Fulton S,Brown JM,Madiraju SR,Prentki M

?/? Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate.
The Journal of biological chemistry290(50)29869-81(2015 Dec)
Pribasnig MA,Mrak I,Grabner GF,Taschler U,Knittelfelder O,Scherz B,Eichmann TO,Heier C,Grumet L,Kowaliuk J,Romauch M,Holler S,Anderl F,Wolinski H,Lass A,Breinbauer R,Marsche G,Brown JM,Zimmermann R

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.
Cell reports5(2)508-20(2013 Oct)
Thomas G,Betters JL,Lord CC,Brown AL,Marshall S,Ferguson D,Sawyer J,Davis MA,Melchior JT,Blume LC,Howlett AC,Ivanova PT,Milne SB,Myers DS,Mrak I,Leber V,Heier C,Taschler U,Blankman JL,Cravatt BF,Lee RG,Crooke RM,Graham MJ,Zimmermann R,Brown HA,Brown JM

Biochemical and pharmacological characterization of human ?/?-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).
Journal of lipid research53(11)2413-24(2012 Nov)
Navia-Paldanius D,Savinainen JR,Laitinen JT

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.
Neuron74(4)621-33(2012 May)
Schwenk J,Harmel N,Brechet A,Zolles G,Berkefeld H,M?ller CS,Bildl W,Baehrens D,H?ber B,Kulik A,Kl?cker N,Schulte U,Fakler B

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Abhd6 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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