Gene Symbol | Ang |
Entrez Gene ID | 305843 |
Full Name | angiogenin |
Synonyms | Ang1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ang cDNA ORF clone
Gene Symbol | Ang |
Entrez Gene ID | 305843 |
Full Name | angiogenin |
Synonyms | Ang1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006251874.3 | XP_006251936.1 | angiogenin isoform X1 |
NM_001006992.1 | NP_001006993.1 | angiogenin precursor |
Ribonuclease 5 coordinates signals for the regulation of intraocular pressure and inhibits neural apoptosis as a novel multi-functional anti-glaucomatous strategy.
Kim KW, Park SH, Oh DH, Lee SH, Lim KS, Joo K, Chun YS, Chang SI, Min KM, Kim JC
Biochimica et biophysica acta1862(2)145-54(2016 Feb)
The dual binding site of angiogenin and its inhibition mechanism: the crystal structure of the rat angiogenin-heparin complex.
Yeo KJ, Hwang E, Min KM, Jee JG, Lee CK, Hwang KY, Jeon YH, Chang SI, Cheong HK
Chemical communications (Cambridge, England)50(85)12966-9(2014 Nov)
Computational and functional characterization of Angiogenin mutations, and correlation with amyotrophic lateral sclerosis.
Padhi AK, Banerjee K, Gomes J, Banerjee M
PloS one9(11)e111963(2014)
Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2.
Li Y, Xia Y, Wang Y, Mao L, Gao Y, He Q, Huang M, Chen S, Hu B
Molecular neurobiology47(3)967-75(2013 Jun)
Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues.
Iyer S, Holloway DE, Acharya KR
The FEBS journal280(1)302-18(2013 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The heparin complex of rat angiogenin revealed that a heparin strand is fitted into a positively charged groove formed by the dual binding site of rat angiogenin.
Title: The dual binding site of angiogenin and its inhibition mechanism: the crystal structure of the rat angiogenin-heparin complex.
oxygen-glucose deprivation could induce the expressions of VEGF, Ang-1, and Ang-2, with the expression of Shh signaling components increased.
Title: Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2.
Ang1 induces neurite outgrowth in PC12 cells in a Tie2-independent, beta1-integrin-FAK-PI3K-Akt-dependent manner. NGF and Ang1 mediate neurite outgrowth via two independent signaling mechanisms.
Title: Angiopoietin-1 induces neurite outgrowth of PC12 cells in a Tie2-independent, beta1-integrin-dependent manner.
The following Ang gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ang cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa42809 | |
Clone ID Related Accession (Same CDS sequence) | NM_001006992.1 | |
Accession Version | NM_001006992.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 438bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | angiogenin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY395869.1. On Nov 22, 2004 this sequence version replaced XM_223968.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY395869.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGGAGATGA GCCTGCGTCC TCTGTTGTCG GTTTTTGTGC TGGGTCTGGT TTCGACCCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001006993.1 |
CDS | 1..438 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001006992.1 |
1 | ATGGAGATGA GCCTGCGTCC TCTGTTGTCG GTTTTTGTGC TGGGTCTGGT TTCGACCCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa36616 | |
Clone ID Related Accession (Same CDS sequence) | XM_006251874.3 | |
Accession Version | XM_006251874.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 600bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | angiogenin isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251874.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTCTCCC CACCCCTTCA CACGAGCCCT GTATATAACC AGACTGACAG GAGCCTCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006251936.1 |
CDS | 4..603 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006251874.3 |
1 | ATGTTCTCCC CACCCCTTCA CACGAGCCCT GTATATAACC AGACTGACAG GAGCCTCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Ribonuclease 5 coordinates signals for the regulation of intraocular pressure and inhibits neural apoptosis as a novel multi-functional anti-glaucomatous strategy. |
The dual binding site of angiogenin and its inhibition mechanism: the crystal structure of the rat angiogenin-heparin complex. |
Computational and functional characterization of Angiogenin mutations, and correlation with amyotrophic lateral sclerosis. |
Sonic hedgehog (Shh) regulates the expression of angiogenic growth factors in oxygen-glucose-deprived astrocytes by mediating the nuclear receptor NR2F2. |
Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues. |