Gene Symbol | Sall2 |
Entrez Gene ID | 305854 |
Full Name | spalt-like transcription factor 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Sall2 cDNA ORF clone
Gene Symbol | Sall2 |
Entrez Gene ID | 305854 |
Full Name | spalt-like transcription factor 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001107262.1 | NP_001100732.1 | sal-like protein 2 |
XM_006251884.3 | XP_006251946.1 | sal-like protein 2 isoform X1 |
Mutation of SALL2 causes recessive ocular coloboma in humans and mice.
Kelberman D, Islam L, Lakowski J, Bacchelli C, Chanudet E, Lescai F, Patel A, Stupka E, Buck A, Wolf S, Beales PL, Jacques TS, Bitner-Glindzicz M, Liasis A, Lehmann OJ, Kohlhase J, Nischal KK, Sowden JC
Human molecular genetics23(10)2511-26(2014 May)
DNA-binding and regulatory properties of the transcription factor and putative tumor suppressor p150(Sal2).
Gu H, Li D, Sung CK, Yim H, Troke P, Benjamin T
Biochimica et biophysica acta1809(4-6)276-83(2011 Apr-Jun)
Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth.
Pincheira R, Baerwald M, Dunbar JD, Donner DB
The EMBO journal28(3)261-73(2009 Feb)
Sall1, sall2, and sall4 are required for neural tube closure in mice.
B?hm J, Buck A, Borozdin W, Mannan AU, Matysiak-Scholze U, Adham I, Schulz-Schaeffer W, Floss T, Wurst W, Kohlhase J, Barrionuevo F
The American journal of pathology173(5)1455-63(2008 Nov)
A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex.
Lauberth SM, Rauchman M
The Journal of biological chemistry281(33)23922-31(2006 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These data establish Sall2 as a link between p75 neurotrophin receptor and transcriptional events that regulate the growth and development of neuronal cells.
Title: Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth.
The following Sall2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sall2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa03199 | |
Clone ID Related Accession (Same CDS sequence) | NM_001107262.1 | |
Accession Version | NM_001107262.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3015bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sal-like protein 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474040.1. On Oct 4, 2007 this sequence version replaced XM_223992.4. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCTCGGC GAAAGCAGCG GAGACCCCAG CAGTTAATCT CGGACTGTGA AGGTCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001100732.1 |
CDS | 596..3610 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001107262.1 |
1 | ATGTCTCGGC GAAAGCAGCG GAGACCCCAG CAGTTAATCT CGGACTGTGA AGGTCCCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa36620 | |
Clone ID Related Accession (Same CDS sequence) | XM_006251884.3 | |
Accession Version | XM_006251884.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3009bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | sal-like protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251884.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGCAGG AAACCGGGAA CGGCTCTCGA CTCGGGGGTC CCTGCGCGGA GCCTGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006251946.1 |
CDS | 169..3177 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006251884.3 |
1 | ATGGCGCAGG AAACCGGGAA CGGCTCTCGA CTCGGGGGTC CCTGCGCGGA GCCTGCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutation of SALL2 causes recessive ocular coloboma in humans and mice. |
DNA-binding and regulatory properties of the transcription factor and putative tumor suppressor p150(Sal2). |
Sall2 is a novel p75NTR-interacting protein that links NGF signalling to cell cycle progression and neurite outgrowth. |
Sall1, sall2, and sall4 are required for neural tube closure in mice. |
A conserved 12-amino acid motif in Sall1 recruits the nucleosome remodeling and deacetylase corepressor complex. |