Gene Symbol | Adamts16 |
Entrez Gene ID | 306664 |
Full Name | ADAM metallopeptidase with thrombospondin type 1 motif, 16 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Adamts16 cDNA ORF clone
gRNAs
Gene Symbol | Adamts16 |
Entrez Gene ID | 306664 |
Full Name | ADAM metallopeptidase with thrombospondin type 1 motif, 16 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_003753157.4 | XP_003753205.1 | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1 |
XM_006222882.3 | XP_006222944.1 | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X2 |
XM_008774310.2 | XP_008772532.1 | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X3 |
XM_003748684.4 | XP_003748732.1 | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1 |
NM_001372015.1 | NP_001358944.1 | A disintegrin and metalloproteinase with thrombospondin motifs 16 precursor |
Canis lupus familiaris (dog) | ADAMTS16 | XP_005639761.1 |
Xenopus tropicalis (tropical clawed frog) | adamts16 | XP_002935179.2 |
ADAMTS16 | XP_001082662.1 | |
Danio rerio (zebrafish) | adamts16 | XP_001922446.3 |
Homo sapiens (human) | ADAMTS16 | NP_620687.2 |
Rattus norvegicus (Norway rat) | Adamts16 | XP_003748732.1 |
Mus musculus (house mouse) | Adamts16 | NP_742050.2 |
Pan troglodytes (chimpanzee) | ADAMTS16 | XP_526829.2 |
Bos taurus (cattle) | ADAMTS16 | XP_002696504.3 |
Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus.
Abdul-Majeed S, Mell B, Nauli SM, Joe B
PloS one9(7)e100967(2014)
Transcriptional regulation by the Wilms tumor protein, Wt1, suggests a role of the metalloproteinase Adamts16 in murine genitourinary development.
Jacobi CL, Rudigier LJ, Scholz H, Kirschner KM
The Journal of biological chemistry288(26)18811-24(2013 Jun)
Targeted disruption of Adamts16 gene in a rat genetic model of hypertension.
Gopalakrishnan K, Kumarasamy S, Abdul-Majeed S, Kalinoski AL, Morgan EE, Gohara AF, Nauli SM, Filipiak WE, Saunders TL, Joe B
Proceedings of the National Academy of Sciences of the United States of America109(50)20555-9(2012 Dec)
Positional identification of variants of Adamts16 linked to inherited hypertension.
Joe B, Saad Y, Dhindaw S, Lee NH, Frank BC, Achinike OH, Luu TV, Gopalakrishnan K, Toland EJ, Farms P, Yerga-Woolwine S, Manickavasagam E, Rapp JP, Garrett MR, Coe D, Apte SS, Rankinen T, P?russe L, Ehret GB, Ganesh SK, Cooper RS, O'Connor A, Rice T, Weder AB, Chakravarti A, Rao DC, Bouchard C
Human molecular genetics18(15)2825-38(2009 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These observations, taken together with our previous report of renal abnormalities observed with the same Adamts16mutant rats, suggest an important mechanistic link between Adamts16 and the functioning of the male genitourinary system.
Title: Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus.
physiological observations functionally link Adamts16 to blood pressure regulation and suggest the vasculature as the potential site of action of Adamts16 to lower blood pressure
Title: Targeted disruption of Adamts16 gene in a rat genetic model of hypertension.
Genetic variation of Adamts16 is linked to inherited hypertension in a rat model.
Title: Positional identification of variants of Adamts16 linked to inherited hypertension.
The following Adamts16 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adamts16 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa14034 | |
Clone ID Related Accession (Same CDS sequence) | XM_006222882.3 | |
Accession Version | XM_006222882.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2976bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000069.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006222882.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACAACTT TCACCTTGGC CTCTCACGAA AGCAGCATTT CTGTGGAAGA CGCAAGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006222944.1 |
CDS | 101..3076 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACAACTT TCACCTTGGC CTCTCACGAA AGCAGCATTT CTGTGGAAGA CGCAAGAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa46437 | |
Clone ID Related Accession (Same CDS sequence) | XM_008774310.2 | |
Accession Version | XM_008774310.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2961bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000069.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008774310.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008772532.1 |
CDS | 223..3183 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa14031 | |
Clone ID Related Accession (Same CDS sequence) | XM_003753157.4 , XM_003748684.4 , NM_001372015.1 | |
Accession Version | NM_001372015.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3666bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-31 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A disintegrin and metalloproteinase with thrombospondin motifs 16 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07001035.1, AABR07001036.1, AABR07001037.1 and AABR07001039.1. On or before Aug 1, 2019 this sequence version replaced XM_003748684.4, XM_003753157.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN04563757, SAMN04563758 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001358944.1 |
CDS | 223..3888 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa14031 | |
Clone ID Related Accession (Same CDS sequence) | XM_003753157.4 , XM_003748684.4 , NM_001372015.1 | |
Accession Version | XM_003753157.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3666bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000069.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003753157.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_003753205.1 |
CDS | 222..3887 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa14031 | |
Clone ID Related Accession (Same CDS sequence) | XM_003753157.4 , XM_003748684.4 , NM_001372015.1 | |
Accession Version | XM_003748684.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3666bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | A disintegrin and metalloproteinase with thrombospondin motifs 16 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_003748684.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_003748732.1 |
CDS | 223..3888 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGAACCCC GCGGTTGCTT TGCGCTCTGG GTGCTGTTGC TGGCGCAGCT CAGTGAGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cryptorchidism and infertility in rats with targeted disruption of the Adamts16 locus. |
Transcriptional regulation by the Wilms tumor protein, Wt1, suggests a role of the metalloproteinase Adamts16 in murine genitourinary development. |
Targeted disruption of Adamts16 gene in a rat genetic model of hypertension. |
Positional identification of variants of Adamts16 linked to inherited hypertension. |