Gene Symbol | Ctnna1 |
Entrez Gene ID | 307505 |
Full Name | catenin alpha 1 |
Synonyms | Catna1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ctnna1 cDNA ORF clone
Gene Symbol | Ctnna1 |
Entrez Gene ID | 307505 |
Full Name | catenin alpha 1 |
Synonyms | Catna1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001007145.1 | NP_001007146.1 | catenin alpha-1 |
XM_008772037.2 | XP_008770259.1 | catenin alpha-1 isoform X2 |
XM_017600965.1 | XP_017456454.1 | catenin alpha-1 isoform X3 |
XM_017600964.1 | XP_017456453.1 | catenin alpha-1 isoform X1 |
CTNNA1 | XP_001113555.2 | |
Gallus gallus (chicken) | CTNNA1 | XP_414513.1 |
Homo sapiens (human) | CTNNA1 | NP_001894.2 |
Mus musculus (house mouse) | Ctnna1 | NP_033948.1 |
Xenopus tropicalis (tropical clawed frog) | ctnna1 | XP_002932348.2 |
Pan troglodytes (chimpanzee) | CTNNA1 | XP_001172013.1 |
Canis lupus familiaris (dog) | CTNNA1 | XP_003431682.1 |
Bos taurus (cattle) | CTNNA1 | NP_001030443.1 |
Rattus norvegicus (Norway rat) | Ctnna1 | NP_001007146.1 |
Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation.
Caldwell JM, Collins MH, Kemme KA, Sherrill JD, Wen T, Rochman M, Stucke EM, Amin L, Tai H, Putnam PE, Jim?nez-Dalmaroni MJ, Wormald MR, Porollo A, Abonia JP, Rothenberg ME
Mucosal immunology10(5)1190-1201(2017 Sep)
Annexin-1 Mediates Microglial Activation and Migration via the CK2 Pathway during Oxygen-Glucose Deprivation/Reperfusion.
Liu S, Gao Y, Yu X, Zhao B, Liu L, Zhao Y, Luo Z, Shi J
International journal of molecular sciences17(10)(2016 Oct)
Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK.
Bear MD, Liu T, Abualkhair S, Ghamloush MA, Hill NS, Preston I, Fanburg BL, Kayyali US, Toksoz D
Journal of cellular physiology231(4)934-43(2016 Apr)
E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)
Loss of ?(E)-catenin potentiates cisplatin-induced nephrotoxicity via increasing apoptosis in renal tubular epithelial cells.
Wang X, Grunz-Borgmann EA, Parrish AR
Toxicological sciences : an official journal of the Society of Toxicology141(1)254-62(2014 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ANXA1 promotes microglial activation and migration during oxygen-glucose deprivation/reperfusion via FPR, and CK2 target alpha-E-catenin phosphorylation is involved in this process.
Title: Annexin-1 Mediates Microglial Activation and Migration via the CK2 Pathway during Oxygen-Glucose Deprivation/Reperfusion.
alpha-catulin has a unique function in co-localization with vimentin filaments that contributes to vascular endothelial cells migration via a pathway that may involve ROCK signaling.
Title: Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK.
Taken together, these data suggest that loss of alpha(E)-catenin increases apoptosis of tubular epithelial cells which may contribute to the increased nephrotoxicity induced by cisplatin in aged kidney.
Title: Loss of ?(E)-catenin potentiates cisplatin-induced nephrotoxicity via increasing apoptosis in renal tubular epithelial cells.
expression of E-cadherin and alpha-catenin was significantly associated with the ROS and degenerative changes in the seminiferous tubules.
Title: Expression of E-cadherin and ?-catenin in a varicocele-induced infertility rat model.
Results provide marker proteins Gap-43 and newly identified candidate neuronal growth-associated proteins MAP1B, CRMP5, crmp5 and catenins.
Title: Identification of functional marker proteins in the mammalian growth cone.
The following Ctnna1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ctnna1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11036 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007145.1 , XM_017600964.1 | |
Accession Version | NM_001007145.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2727bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | catenin alpha-1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085789.1. On Nov 22, 2004 this sequence version replaced XM_226048.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC085789.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACTGCCG TCCACACAGG CAACATAAAC TTCAAATGGG ACCCCAAAAG TCTAGAGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001007146.1 |
CDS | 69..2795 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001007145.1 |
1 | ATGACTGCCG TCCACACAGG CAACATAAAC TTCAAATGGG ACCCCAAAAG TCTAGAGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa11036 | |
Clone ID Related Accession (Same CDS sequence) | NM_001007145.1 , XM_017600964.1 | |
Accession Version | XM_017600964.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2727bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | catenin alpha-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTGCCG TCCACACAGG CAACATAAAC TTCAAATGGG ACCCCAAAAG TCTAGAGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017456453.1 |
CDS | 210..2936 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017600964.1 |
1 | ATGACTGCCG TCCACACAGG CAACATAAAC TTCAAATGGG ACCCCAAAAG TCTAGAGATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa46509 | |
Clone ID Related Accession (Same CDS sequence) | XM_008772037.2 | |
Accession Version | XM_008772037.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | catenin alpha-1 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008772037.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACCAAGA AGACCAGGGA CCTGCGTCGA CAGCTTCGCA AAGCTGTCAT GGACCACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008770259.1 |
CDS | 138..1748 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008772037.2 |
1 | ATGACCAAGA AGACCAGGGA CCTGCGTCGA CAGCTTCGCA AAGCTGTCAT GGACCACGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa59274 | |
Clone ID Related Accession (Same CDS sequence) | XM_017600965.1 | |
Accession Version | XM_017600965.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1563bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | catenin alpha-1 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACCACG TATCAGATTC CTTCCTGGAG ACCAATGTCC CTCTTTTAGT ACTGATTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017456454.1 |
CDS | 140..1702 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017600965.1 |
1 | ATGGACCACG TATCAGATTC CTTCCTGGAG ACCAATGTCC CTCTTTTAGT ACTGATTGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation. |
Annexin-1 Mediates Microglial Activation and Migration via the CK2 Pathway during Oxygen-Glucose Deprivation/Reperfusion. |
Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK. |
E-cadherin interactome complexity and robustness resolved by quantitative proteomics. |
Loss of ?(E)-catenin potentiates cisplatin-induced nephrotoxicity via increasing apoptosis in renal tubular epithelial cells. |