| Gene Symbol | Dchs1 |
| Entrez Gene ID | 308912 |
| Full Name | dachsous cadherin-related 1 |
| Synonyms | Pcdh16 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
gRNAs
The following Dchs1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dchs1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa13532 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107544.2 , XM_006229942.2 | |
| Accession Version | NM_001107544.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 9876bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-02-21 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protocadherin-16 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07071958.1. On Jul 1, 2009 this sequence version replaced NM_001107544.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2689601 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCAGGAGG AGCTAAGTGT TGCACTCTCC TGCCCTGGCA TGAAGAGCCT CGGGACTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001101014.2 |
| CDS | 115..9990 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107544.2 |
1 | ATGCAGGAGG AGCTAAGTGT TGCACTCTCC TGCCCTGGCA TGAAGAGCCT CGGGACTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa13532 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107544.2 , XM_006229942.2 | |
| Accession Version | XM_006229942.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 9876bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | protocadherin-16 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006229942.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCAGGAGG AGCTAAGTGT TGCACTCTCC TGCCCTGGCA TGAAGAGCCT CGGGACTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006230004.1 |
| CDS | 304..10179 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006229942.2 |
1 | ATGCAGGAGG AGCTAAGTGT TGCACTCTCC TGCCCTGGCA TGAAGAGCCT CGGGACTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Mutations in DCHS1 cause mitral valve prolapse. |
Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. |
Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development. |
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development. |
Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex. |
