Gene Symbol | Ppa2 |
Entrez Gene ID | 310856 |
Full Name | pyrophosphatase (inorganic) 2 |
Synonyms | RGD1307965 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ppa2 cDNA ORF clone
gRNAs
Gene Symbol | Ppa2 |
Entrez Gene ID | 310856 |
Full Name | pyrophosphatase (inorganic) 2 |
Synonyms | RGD1307965 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006233327.3 | XP_006233389.1 | inorganic pyrophosphatase 2, mitochondrial isoform X1 |
NM_001135871.1 | NP_001129343.1 | inorganic pyrophosphatase 2, mitochondrial |
Homo sapiens (human) | PPA2 | NP_789845.1 |
Rattus norvegicus (Norway rat) | Ppa2 | NP_001129343.1 |
Pan troglodytes (chimpanzee) | PPA2 | XP_517378.2 |
Canis lupus familiaris (dog) | PPA2 | XP_535679.3 |
Xenopus tropicalis (tropical clawed frog) | ppa1 | NP_001017130.1 |
PPA2 | XP_001082969.2 | |
Mus musculus (house mouse) | Ppa2 | NP_666253.1 |
Danio rerio (zebrafish) | ppa1a | NP_957027.1 |
Bos taurus (cattle) | PPA2 | NP_001069864.1 |
Gallus gallus (chicken) | PPA2 | XP_420502.3 |
Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase PPA2.
Kennedy H, Haack TB, Hartill V, Matakovi? L, Baumgartner ER, Potter H, Mackay R, Alston CL, O'Sullivan S, McFarland R, Connolly G, Gannon C, King R, Mead S, Crozier I, Chan W, Florkowski CM, Sage M, H?fken T, Alhaddad B, Kremer LS, Kopajtich R, Feichtinger RG, Sperl W, Rodenburg RJ, Minet JC, Dobbie A, Strom TM, Meitinger T, George PM, Johnson CA, Taylor RW, Prokisch H, Doudney K, Mayr JA
American journal of human genetics99(3)674-682(2016 Sep)
Biallelic PPA2 Mutations Cause Sudden Unexpected Cardiac Arrest in Infancy.
Guimier A, Gordon CT, Godard F, Ravenscroft G, Oufadem M, Vasnier C, Rambaud C, Nitschke P, Bole-Feysot C, Masson C, Dauger S, Longman C, Laing NG, Kugener B, Bonnet D, Bouvagnet P, Di Filippo S, Probst V, Redon R, Charron P, R?tig A, Lyonnet S, Dautant A, de Pontual L, di Rago JP, Delahodde A, Amiel J
American journal of human genetics99(3)666-673(2016 Sep)
Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis.
Xing Y, Igarashi H, Wang X, Sakaguchi N
The Journal of experimental medicine202(5)707-19(2005 Sep)
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Mootha VK, Bunkenborg J, Olsen JV, Hjerrild M, Wisniewski JR, Stahl E, Bolouri MS, Ray HN, Sihag S, Kamal M, Patterson N, Lander ES, Mann M
Cell115(5)629-40(2003 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Ppa2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppa2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa04144 | |
Clone ID Related Accession (Same CDS sequence) | NM_001135871.1 | |
Accession Version | NM_001135871.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 993bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-12 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | inorganic pyrophosphatase 2, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07013467.1 and AABR07013468.1. On Oct 16, 2008 this sequence version replaced XM_227690.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGCGCGCGC TGCTGCCACT GCTGAGCGTC GGCCGAGGGT GGCGCGTGGG GGCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129343.1 |
CDS | 1..993 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCGCGCGC TGCTGCCACT GCTGAGCGTC GGCCGAGGGT GGCGCGTGGG GGCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa25274 | |
Clone ID Related Accession (Same CDS sequence) | XM_006233327.3 | |
Accession Version | XM_006233327.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 990bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | inorganic pyrophosphatase 2, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233327.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCGCGC TGCTGCCACT GCTGAGCGTC GGCCGAGGGT GGCGCGTGGG GGCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006233389.1 |
CDS | 95..1084 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCGCGCGC TGCTGCCACT GCTGAGCGTC GGCCGAGGGT GGCGCGTGGG GGCCGCCGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase PPA2. |
Biallelic PPA2 Mutations Cause Sudden Unexpected Cardiac Arrest in Infancy. |
Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis. |
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |