| Gene Symbol | Dusp19 |
| Entrez Gene ID | 311151 |
| Full Name | dual specificity phosphatase 19 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Dusp19 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dusp19 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa05800 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107739.2 | |
| Accession Version | NM_001107739.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 663bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-07-28 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | dual specificity protein phosphatase 19 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07052648.1. On Jan 1, 2009 this sequence version replaced NM_001107739.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: FM114648.1, FM098635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCACTCCC TGAACCAAGA AATCAAAGCA TTCTCCCGGG ATAATCTCAG GAAGCAGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001101209.2 |
| CDS | 159..821 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107739.2 |
1 | ATGCACTCCC TGAACCAAGA AATCAAAGCA TTCTCCCGGG ATAATCTCAG GAAGCAGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
DUSP19 regulates IL-1?-induced apoptosis and MMPs expression in rat chondrocytes through JAK2/STAT3 signaling pathway. |
DUSP19, a downstream effector of leptin, inhibits chondrocyte apoptosis via dephosphorylating JNK during osteoarthritis pathogenesis. |
A novel dual specificity phosphatase SKRP1 interacts with the MAPK kinase MKK7 and inactivates the JNK MAPK pathway. Implication for the precise regulation of the particular MAPK pathway. |
Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathway. |
A growing family of dual specificity phosphatases with low molecular masses. |
