Gene Symbol | Ttbk2 |
Entrez Gene ID | 311349 |
Full Name | tau tubulin kinase 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ttbk2 cDNA ORF clone
Gene Symbol | Ttbk2 |
Entrez Gene ID | 311349 |
Full Name | tau tubulin kinase 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017591733.1 | XP_017447222.1 | tau-tubulin kinase 2 isoform X2 |
XM_006234835.2 | XP_006234897.1 | tau-tubulin kinase 2 isoform X1 |
XM_006234837.3 | XP_006234899.1 | tau-tubulin kinase 2 isoform X1 |
NM_001107766.1 | NP_001101236.1 | tau-tubulin kinase 2 |
XM_006234833.2 | XP_006234895.1 | tau-tubulin kinase 2 isoform X1 |
XM_006234834.3 | XP_006234896.1 | tau-tubulin kinase 2 isoform X1 |
Rattus norvegicus (Norway rat) | Ttbk2 | NP_001101236.1 |
Xenopus tropicalis (tropical clawed frog) | ttbk2 | NP_001072838.1 |
Mus musculus (house mouse) | Ttbk2 | NP_542966.2 |
TTBK2 | XP_002804790.1 | |
Gallus gallus (chicken) | TTBK2 | XP_004941717.1 |
Homo sapiens (human) | TTBK2 | NP_775771.3 |
Pan troglodytes (chimpanzee) | TTBK2 | XP_001155340.1 |
Canis lupus familiaris (dog) | TTBK2 | XP_005638372.1 |
Bos taurus (cattle) | TTBK2 | NP_001193000.1 |
TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K
The Journal of cell biology210(5)737-51(2015 Aug)
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals.
Ye X, Zeng H, Ning G, Reiter JF, Liu A
Proceedings of the National Academy of Sciences of the United States of America111(6)2164-9(2014 Feb)
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.
Goetz SC, Liem KF Jr, Anderson KV
Cell151(4)847-58(2012 Nov)
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.
B?hm D, Keller K, Pieter J, Boehm N, Wolters D, Siggelkow W, Lebrecht A, Schmidt M, K?lbl H, Pfeiffer N, Grus FH
Oncology reports28(2)429-38(2012 Aug)
TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development.
Bouskila M, Esoof N, Gay L, Fang EH, Deak M, Begley MJ, Cantley LC, Prescott A, Storey KG, Alessi DR
The Biochemical journal437(1)157-67(2011 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Ttbk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ttbk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa60395 | |
Clone ID Related Accession (Same CDS sequence) | XM_017591733.1 | |
Accession Version | XM_017591733.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3270bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tau-tubulin kinase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017447222.1 |
CDS | 521..3790 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017591733.1 |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa05906 | |
Clone ID Related Accession (Same CDS sequence) | NM_001107766.1 | |
Accession Version | NM_001107766.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3636bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tau-tubulin kinase 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473949.1. On or before Oct 4, 2007 this sequence version replaced XM_230495.4, XM_001080916.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689595 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001101236.1 |
CDS | 180..3815 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001107766.1 |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa26269 | |
Clone ID Related Accession (Same CDS sequence) | XM_006234835.2 , XM_006234837.3 , XM_006234833.2 , XM_006234834.3 | |
Accession Version | XM_006234835.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tau-tubulin kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006234835.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006234897.1 |
CDS | 446..4174 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006234835.2 |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa26269 | |
Clone ID Related Accession (Same CDS sequence) | XM_006234835.2 , XM_006234837.3 , XM_006234833.2 , XM_006234834.3 | |
Accession Version | XM_006234837.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tau-tubulin kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234837.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006234899.1 |
CDS | 168..3896 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006234837.3 |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa26269 | |
Clone ID Related Accession (Same CDS sequence) | XM_006234835.2 , XM_006234837.3 , XM_006234833.2 , XM_006234834.3 | |
Accession Version | XM_006234833.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tau-tubulin kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 7, 2014 this sequence version replaced XM_006234833.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006234895.1 |
CDS | 520..4248 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006234833.2 |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa26269 | |
Clone ID Related Accession (Same CDS sequence) | XM_006234835.2 , XM_006234837.3 , XM_006234833.2 , XM_006234834.3 | |
Accession Version | XM_006234834.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tau-tubulin kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006234834.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006234896.1 |
CDS | 751..4479 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006234834.3 |
1 | ATGAGTGGAG GAGGAGAGCA GCCAGATATC CTCAGTGTTG GAATCCTGGT CAAAGAAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation. |
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals. |
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis. |
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. |
TTBK2 kinase substrate specificity and the impact of spinocerebellar-ataxia-causing mutations on expression, activity, localization and development. |