Nelfb cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Nelfb |
| Entrez Gene ID | 311796 |
| Full Name | negative elongation factor complex member B |
| Synonyms | Cobra1,RGD1307832 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001107817.3 | NP_001101287.3 | negative elongation factor B |
| COBRA1 | XP_001087434.1 | |
| Rattus norvegicus (Norway rat) | Nelfb | NP_001101287.2 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012109 | XP_320419.3 |
| Homo sapiens (human) | NELFB | NP_056271.2 |
| Bos taurus (cattle) | NELFB | XP_002691742.3 |
| Xenopus tropicalis (tropical clawed frog) | nelfb | NP_001011448.1 |
| Mus musculus (house mouse) | Nelfb | NP_067368.2 |
| Gallus gallus (chicken) | COBRA1 | NP_001006202.1 |
| Pan troglodytes (chimpanzee) | COBRA1 | XP_001136264.3 |
| Canis lupus familiaris (dog) | NELFB | XP_548351.2 |
| Danio rerio (zebrafish) | nelfb | NP_956462.1 |
| Drosophila melanogaster (fruit fly) | NELF-B | NP_572402.1 |
Related articles in PubMed
Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks.
Williams LH, Fromm G, Gokey NG, Henriques T, Muse GW, Burkholder A, Fargo DC, Hu G, Adelman K
Molecular cell58(2)311-322(2015 Apr)
Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B.
Pan H, Zhao X, Zhang X, Abouelsoud M, Sun J, April C, Amleh A, Fan JB, Hu Y, Li R
PloS one10(5)e0127422(2015)
Negative elongation factor controls energy homeostasis in cardiomyocytes.
Pan H, Qin K, Guo Z, Ma Y, April C, Gao X, Andrews TG, Bokov A, Zhang J, Chen Y, Weintraub ST, Fan JB, Wang D, Hu Y, Aune GJ, Lindsey ML, Li R
Cell reports7(1)79-85(2014 Apr)
A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.
Luo M, Lu X, Zhu R, Zhang Z, Chow CC, Li R, Simons SS Jr
The Journal of biological chemistry288(47)34055-72(2013 Nov)
Control of transcriptional elongation.
Kwak H, Lis JT
Annual review of genetics47483-508(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These studies allow us to position the actions of two new modulators of GR-regulated transactivation, NELF-A and NELF-B, relative to other factors in the overall gene induction sequence.
Title: A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties.
The following Nelfb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Nelfb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa47068 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001107817.3 | |
| Accession Version | NM_001107817.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1896bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-18 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | negative elongation factor B | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07051240.1 and BC160853.1. On Jul 3, 2015 this sequence version replaced NM_001107817.2. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## non-AUG initiation codon :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | CTGGCCACAC TGGAGGCGGC GGGCGAACGG GGCTTGGGTG GTCCTCGTGG CACCGTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001101287.3 |
| CDS | 67..1962 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001107817.3 |
ORF Insert Sequence:
1 | CTGGCCACAC TGGAGGCGGC GGGCGAACGG GGCTTGGGTG GTCCTCGTGG CACCGTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Pausing of RNA polymerase II regulates mammalian developmental potential through control of signaling networks. |
|
Translational Initiation at a Non-AUG Start Codon for Human and Mouse Negative Elongation Factor-B. |
|
Negative elongation factor controls energy homeostasis in cardiomyocytes. |
|
A conserved protein motif is required for full modulatory activity of negative elongation factor subunits NELF-A and NELF-B in modifying glucocorticoid receptor-regulated gene induction properties. |
|
Control of transcriptional elongation. |