Usp18 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Usp18
Entrez Gene ID	312688
Full Name	ubiquitin specific peptidase 18
General protein information	Preferred Names ubiquitin specific peptidase 18 Names ubl carboxyl-terminal hydrolase 18
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q42

mRNA and Protein(s)

mRNA Protein Name

NM_001014058.1 NP_001014080.1 ubl carboxyl-terminal hydrolase 18
Pathways from BioSystems

mRNA	Protein	Name
NM_001014058.1	NP_001014080.1	ubl carboxyl-terminal hydrolase 18

Homologies

Homo sapiens (human)	USP18	NP_059110.2
Pan troglodytes (chimpanzee)	USP18	XP_001164261.1
Canis lupus familiaris (dog)	USP18	XP_005637457.1
Mus musculus (house mouse)	Usp18	NP_036039.2
Rattus norvegicus (Norway rat)	Usp18	NP_001014080.1
Gallus gallus (chicken)	USP18	XP_004938016.1
	USP18	XP_001111984.2
Bos taurus (cattle)	USP18	NP_001017940.1
Xenopus tropicalis (tropical clawed frog)	usp18	XP_004912550.1
Danio rerio (zebrafish)	LOC100334535	XP_002661398.1

Gene Ontology
Bibliography

Related articles in PubMed

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.
Meuwissen ME, Schot R, Buta S, Oudesluijs G, Tinschert S, Speer SD, Li Z, van Unen L, Heijsman D, Goldmann T, Lequin MH, Kros JM, Stam W, Hermann M, Willemsen R, Brouwer RW, Van IJcken WF, Martin-Fernandez M, de Coo I, Dudink J, de Vries FA, Bertoli Avella A, Prinz M, Crow YJ, Verheijen FW, Pellegrini S, Bogunovic D, Mancini GM
The Journal of experimental medicine213(7)1163-74(2016 Jun)

Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)

Resveratrol improves health and survival of mice on a high-calorie diet.
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA
Nature444(7117)337-42(2006 Nov)

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling.
Kim KI, Yan M, Malakhova O, Luo JK, Shen MF, Zou W, de la Torre JC, Zhang DE
Molecular and cellular biology26(2)472-9(2006 Jan)

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Giannakopoulos NV, Luo JK, Papov V, Zou W, Lenschow DJ, Jacobs BS, Borden EC, Li J, Virgin HW, Zhang DE
Biochemical and biophysical research communications336(2)496-506(2005 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Usp18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Usp18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa04809	NM_001014058.1 Latest version!	Rattus norvegicus ubiquitin specific peptidase 18 (Usp18), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Usp18 ( NM_001014058.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001014080.1 Rattus norvegicus ubiquitin specific peptidase 18 (Usp18), mRNA.

Price & Availability↑

CloneID	ORa04809
Clone ID Related Accession (Same CDS sequence)	NM_001014058.1
Accession Version	NM_001014058.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	ubl carboxyl-terminal hydrolase 18
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079101.1. On Apr 20, 2005 this sequence version replaced XM_232259.3. ##Evidence-Data-START## Transcript exon combination :: BC079101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGGGCAAAG GGTTTGGGCT CCTGAGGAAA ACCTGCCAGT CAGTTGTGGC TAATCCTCAG 
CAGCACTCAG CTCTGGAGGA AGAGAAGAAC ATGAAGAGGA AGAGAGTGCT GTCTAGAGAG 
CTCTGCAGTG CCTGGGACCG CCCTCATGGT TTCGTTGGGT TACACAACAT CGGTCAGACA 
TGTTGCCTTA ACTCCTTGAT TCAGGTGTTC ATGATGAATG TGGACTTCAG GATGGTATTG 
AAGAGGATAA CAGTGCCACG AGGGGCAGAA GAACAGAAGA GAAGTGTCCC CTTCCAGCTG 
CTTTTGCTGC TGGAGAAGAT GCAGGACAGC CGGCAGAAGG CAGTGCTGCC CACGGAGCTC 
GTTCAGTGCC TCCAGAAATA CAACGTGCCA TTGTTTGTCC AGCACGATGC TGCTCATCTC 
TTCCTTACAA TCTGGAACCT GACTAAGGAC CAGATCACGG ACATAGACTT GGCAGAGCGG 
CTGCAGGATC TGTTCACAAT CTGGACCGAG GAGTCCCTGA TGTGCGTGGG CTGTGGAGCA 
GAGAGCAGCA GGAGGGGCAA GTTGCTCACT CTCTCTCTTC CTCTTTTTGA TATGGATTCA 
AAGCCCCTAA AAACACTGGA GGATGCCTTG AGATGTTTCT TCCAGCCCAA AGAGTTAGCA 
AGCTCAGACA AGTGCTTCTG TGAGACCTGC GGGAAGAAGA CGCCTTGCAA ACAGGCTCAG 
AAGCTGACTG GTTTCCCTCA GACCCTGACC ATCCACCTCA TGAGATTCTC TGTCAGGAAC 
TCACAGACAG TAAAGATCTG CCACTCAGTG TACTTCCCGC AGAGCTTGGA TTTCAGTCAG 
ATTCTGCCAA CCACGGATCA GTCTGAGATA CACTATGAAC TCTTTGCTGT GATTGCCCAT 
GTTGGGATGG CAGACTTCGG TCATTACTGT GCCTACATCC GGAATCCCGT GGATGGAGAA 
TGGTTCTGCT TCAATGATTC ACATGTTTGT TGGGTGACCT GGAAGGATGT CCAGTGTACC 
TATGGGGATC ACATATATCG TTGGAGGGAA ACTGCCTATC TCTTGGTTTA CATGAAGACT 
GGATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001014080.1
CDS	119..1207
Translation	MGKGFGLLRKTCQSVVANPQQHSALEEEKNMKRKRVLSRELCSAWDRPHGFVGLHNIGQTCCLNSLIQVFMMNVDFRMVLKRITVPRGAEEQKRSVPFQLLLLLEKMQDSRQKAVLPTELVQCLQKYNVPLFVQHDAAHLFLTIWNLTKDQITDIDLAERLQDLFTIWTEESLMCVGCGAESSRRGKLLTLSLPLFDMDSKPLKTLEDALRCFFQPKELASSDKCFCETCGKKTPCKQAQKLTGFPQTLTIHLMRFSVRNSQTVKICHSVYFPQSLDFSQILPTTDQSEIHYELFAVIAHVGMADFGHYCAYIRNPVDGEWFCFNDSHVCWVTWKDVQCTYGDHIYRWRETAYLLVYMKTGS

Target ORF information:

RefSeq Version	NM_001014058.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ubiquitin specific peptidase 18 (Usp18), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001014058.1

ORF Insert Sequence:

ATGGGCAAAG GGTTTGGGCT CCTGAGGAAA ACCTGCCAGT CAGTTGTGGC TAATCCTCAG 
CAGCACTCAG CTCTGGAGGA AGAGAAGAAC ATGAAGAGGA AGAGAGTGCT GTCTAGAGAG 
CTCTGCAGTG CCTGGGACCG CCCTCATGGT TTCGTTGGGT TACACAACAT CGGTCAGACA 
TGTTGCCTTA ACTCCTTGAT TCAGGTGTTC ATGATGAATG TGGACTTCAG GATGGTATTG 
AAGAGGATAA CAGTGCCACG AGGGGCAGAA GAACAGAAGA GAAGTGTCCC CTTCCAGCTG 
CTTTTGCTGC TGGAGAAGAT GCAGGACAGC CGGCAGAAGG CAGTGCTGCC CACGGAGCTC 
GTTCAGTGCC TCCAGAAATA CAACGTGCCA TTGTTTGTCC AGCACGATGC TGCTCATCTC 
TTCCTTACAA TCTGGAACCT GACTAAGGAC CAGATCACGG ACATAGACTT GGCAGAGCGG 
CTGCAGGATC TGTTCACAAT CTGGACCGAG GAGTCCCTGA TGTGCGTGGG CTGTGGAGCA 
GAGAGCAGCA GGAGGGGCAA GTTGCTCACT CTCTCTCTTC CTCTTTTTGA TATGGATTCA 
AAGCCCCTAA AAACACTGGA GGATGCCTTG AGATGTTTCT TCCAGCCCAA AGAGTTAGCA 
AGCTCAGACA AGTGCTTCTG TGAGACCTGC GGGAAGAAGA CGCCTTGCAA ACAGGCTCAG 
AAGCTGACTG GTTTCCCTCA GACCCTGACC ATCCACCTCA TGAGATTCTC TGTCAGGAAC 
TCACAGACAG TAAAGATCTG CCACTCAGTG TACTTCCCGC AGAGCTTGGA TTTCAGTCAG 
ATTCTGCCAA CCACGGATCA GTCTGAGATA CACTATGAAC TCTTTGCTGT GATTGCCCAT 
GTTGGGATGG CAGACTTCGG TCATTACTGT GCCTACATCC GGAATCCCGT GGATGGAGAA 
TGGTTCTGCT TCAATGATTC ACATGTTTGT TGGGTGACCT GGAAGGATGT CCAGTGTACC 
TATGGGGATC ACATATATCG TTGGAGGGAA ACTGCCTATC TCTTGGTTTA CATGAAGACT 
GGATCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome.
The Journal of experimental medicine213(7)1163-74(2016 Jun)
Meuwissen ME,Schot R,Buta S,Oudesluijs G,Tinschert S,Speer SD,Li Z,van Unen L,Heijsman D,Goldmann T,Lequin MH,Kros JM,Stam W,Hermann M,Willemsen R,Brouwer RW,Van IJcken WF,Martin-Fernandez M,de Coo I,Dudink J,de Vries FA,Bertoli Avella A,Prinz M,Crow YJ,Verheijen FW,Pellegrini S,Bogunovic D,Mancini GM

Impact of lactobacilli on orally acquired listeriosis.
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
Archambaud C,Nahori MA,Soubigou G,B?cavin C,Laval L,Lechat P,Smokvina T,Langella P,Lecuit M,Cossart P

Resveratrol improves health and survival of mice on a high-calorie diet.
Nature444(7117)337-42(2006 Nov)
Baur JA,Pearson KJ,Price NL,Jamieson HA,Lerin C,Kalra A,Prabhu VV,Allard JS,Lopez-Lluch G,Lewis K,Pistell PJ,Poosala S,Becker KG,Boss O,Gwinn D,Wang M,Ramaswamy S,Fishbein KW,Spencer RG,Lakatta EG,Le Couteur D,Shaw RJ,Navas P,Puigserver P,Ingram DK,de Cabo R,Sinclair DA

Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling.
Molecular and cellular biology26(2)472-9(2006 Jan)
Kim KI,Yan M,Malakhova O,Luo JK,Shen MF,Zou W,de la Torre JC,Zhang DE

Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Biochemical and biophysical research communications336(2)496-506(2005 Oct)
Giannakopoulos NV,Luo JK,Papov V,Zou W,Lenschow DJ,Jacobs BS,Borden EC,Li J,Virgin HW,Zhang DE

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Usp18 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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