| Gene Symbol | C1r |
| Entrez Gene ID | 312705 |
| Full Name | complement C1r |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following C1r gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C1r cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa02727 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001134555.1 | |
| Accession Version | NM_001134555.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-27 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | complement C1r subcomponent precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC168673.1. On or before Sep 7, 2008 this sequence version replaced XM_242644.4, XM_001061611.1. ##Evidence-Data-START## Transcript exon combination :: BC168673.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCGTCTCA TCCCCCTCCT CCTGGTGACC CTGTTCTGTG GGGTGGAGGG CTCCATCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001128027.1 |
| CDS | 80..2203 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001134555.1 |
1 | ATGCGTCTCA TCCCCCTCCT CCTGGTGACC CTGTTCTGTG GGGTGGAGGG CTCCATCTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. |
Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r. |
Alterations of the classic pathway of complement in adipose tissue of obesity and insulin resistance. |
The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex. |
