Gene Symbol | Papola |
Entrez Gene ID | 314417 |
Full Name | poly (A) polymerase alpha |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Papola cDNA ORF clone
gRNAs
Gene Symbol | Papola |
Entrez Gene ID | 314417 |
Full Name | poly (A) polymerase alpha |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001108056.2 | NP_001101526.1 | poly(A) polymerase alpha |
XM_006240521.3 | XP_006240583.1 | poly(A) polymerase alpha isoform X1 |
XM_008764808.2 | XP_008763030.1 | poly(A) polymerase alpha isoform X3 |
XM_008764810.2 | XP_008763032.1 | poly(A) polymerase alpha isoform X5 |
XM_008764809.2 | XP_008763031.1 | poly(A) polymerase alpha isoform X4 |
XM_008764807.2 | XP_008763029.1 | poly(A) polymerase alpha isoform X2 |
Bos taurus (cattle) | PAPOLA | NP_788820.1 |
Rattus norvegicus (Norway rat) | Papola | NP_001101526.1 |
Gallus gallus (chicken) | PAPOLA | NP_001185530.1 |
Oryza sativa (rice) | Os06g0558700 | NP_001174846.1 |
PAPOLA | XP_002805246.1 | |
Mus musculus (house mouse) | Papola | NP_035242.1 |
Caenorhabditis elegans (roundworm) | pap-1 | NP_505683.1 |
Caenorhabditis elegans (roundworm) | T15H9.6 | NP_496067.1 |
Danio rerio (zebrafish) | papola | NP_991321.2 |
Caenorhabditis elegans (roundworm) | CELE_F43G6.5 | NP_496524.1 |
Arabidopsis thaliana (thale cress) | PAPS2 | NP_001031417.1 |
Oryza sativa (rice) | Os02g0227400 | NP_001046352.2 |
Xenopus tropicalis (tropical clawed frog) | papola | NP_001136382.1 |
Homo sapiens (human) | PAPOLA | NP_116021.2 |
Pan troglodytes (chimpanzee) | PAPOLA | XP_003314562.1 |
Canis lupus familiaris (dog) | PAPOLA | XP_005623838.1 |
Arabidopsis thaliana (thale cress) | nPAP | NP_974668.1 |
Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors.
Gruber AR, Martin G, Keller W, Zavolan M
Wiley interdisciplinary reviews. RNA5(2)183-96(2014 Mar-Apr)
Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.
Kiefer H, Mizutani A, Iemura S, Natsume T, Ando H, Kuroda Y, Mikoshiba K
The Journal of biological chemistry284(16)10694-705(2009 Apr)
ERK is a novel regulatory kinase for poly(A) polymerase.
Lee SH, Choi HS, Kim H, Lee Y
Nucleic acids research36(3)803-13(2008 Feb)
The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation.
Murthy KG, Manley JL
Genes & development9(21)2672-83(1995 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Papola gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Papola cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa06591 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108056.2 | |
Accession Version | NM_001108056.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-30 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) polymerase alpha | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC125847.4, AABR07073261.1 and AABR07065460.1. On Jul 21, 2011 this sequence version replaced NM_001108056.1. ##Evidence-Data-START## Transcript exon combination :: BC083612.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001101526.1 |
CDS | 206..2425 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa29595 | |
Clone ID Related Accession (Same CDS sequence) | XM_006240521.3 | |
Accession Version | XM_006240521.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) polymerase alpha isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006240521.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006240583.1 |
CDS | 211..2487 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47322 | |
Clone ID Related Accession (Same CDS sequence) | XM_008764807.2 | |
Accession Version | XM_008764807.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) polymerase alpha isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764807.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008763029.1 |
CDS | 212..2485 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47323 | |
Clone ID Related Accession (Same CDS sequence) | XM_008764808.2 | |
Accession Version | XM_008764808.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2217bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) polymerase alpha isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764808.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008763030.1 |
CDS | 211..2427 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47324 | |
Clone ID Related Accession (Same CDS sequence) | XM_008764809.2 | |
Accession Version | XM_008764809.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2214bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) polymerase alpha isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764809.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008763031.1 |
CDS | 211..2424 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47325 | |
Clone ID Related Accession (Same CDS sequence) | XM_008764810.2 | |
Accession Version | XM_008764810.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2157bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | poly(A) polymerase alpha isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005105.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008764810.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008763032.1 |
CDS | 211..2367 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCCGTTTC CAGTTACAAC GCAGGGATCA CAACAAACGC AGCCGCCACA GAGGCACTAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors. |
Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation. |
ERK is a novel regulatory kinase for poly(A) polymerase. |
The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. |