Gene Symbol | Tab1 |
Entrez Gene ID | 315139 |
Full Name | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
Synonyms | Map3k7ip1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Tab1 cDNA ORF clone
gRNAs
Gene Symbol | Tab1 |
Entrez Gene ID | 315139 |
Full Name | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
Synonyms | Map3k7ip1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001109976.2 | NP_001103446.1 | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 |
TAB1 | XP_002798398.1 | |
Mus musculus (house mouse) | Tab1 | NP_079885.2 |
Rattus norvegicus (Norway rat) | Tab1 | NP_001103446.1 |
Homo sapiens (human) | TAB1 | NP_006107.1 |
Canis lupus familiaris (dog) | TAB1 | XP_538366.4 |
Pan troglodytes (chimpanzee) | TAB1 | XP_515141.3 |
Gallus gallus (chicken) | TAB1 | NP_001006240.1 |
Xenopus tropicalis (tropical clawed frog) | tab1 | NP_001016463.1 |
Danio rerio (zebrafish) | tab1 | XP_002662286.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002953 | XP_311946.5 |
Global genetic analysis in mice unveils central role for cilia in congenital heart disease.
Li Y, Klena NT, Gabriel GC, Liu X, Kim AJ, Lemke K, Chen Y, Chatterjee B, Devine W, Damerla RR, Chang C, Yagi H, San Agustin JT, Thahir M, Anderton S, Lawhead C, Vescovi A, Pratt H, Morgan J, Haynes L, Smith CL, Eppig JT, Reinholdt L, Francis R, Leatherbury L, Ganapathiraju MK, Tobita K, Pazour GJ, Lo CW
Nature521(7553)520-4(2015 May)
Immunolocalization of TAK1, TAB1, and p38 in the developing rat molar.
Moriguchi M, Yamada M, Miake Y, Yanagisawa T
Anatomical science international86(2)69-77(2011 Jun)
TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.
Brown J, Wang H, Hajishengallis GN, Martin M
Journal of dental research90(4)417-27(2011 Apr)
Expanding role of ubiquitination in NF-?B signaling.
Liu S, Chen ZJ
Cell research21(1)6-21(2011 Jan)
Magnesium Lithospermate B Protects Cardiomyocytes from Ischemic Injury Via Inhibition of TAB1-p38 Apoptosis Signaling.
Du CS, Yang RF, Song SW, Wang YP, Kang JH, Zhang R, Su DF, Xie X
Frontiers in pharmacology1111(2010)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
TGF-beta or BMP is involved in molar development through the non-Smad signaling pathway via TAK1, TAB1 and p38 as well as Smad signaling pathways.
Title: Immunolocalization of TAK1, TAB1, and p38 in the developing rat molar.
TGF-beta3 selectively disrupts Sertoli-germ cell adhesion in the seminiferous epithelium to facilitate germ cell migration without compromising BTB when TbetaRI interacts only with adaptor CD2AP.
Title: Differential interactions between transforming growth factor-beta3/TbetaR1, TAB1, and CD2AP disrupt blood-testis barrier and Sertoli-germ cell adhesion.
Data suggest that TAB-1 can mediate MKK-independent p38 kinase activation while negatively modulating MKK-dependent p38 function.
Title: TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling.
The following Tab1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tab1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa00730 | |
Clone ID Related Accession (Same CDS sequence) | NM_001109976.2 | |
Accession Version | NM_001109976.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB802111.1, CB605878.1, EV771639.1, DY311072.1, DN948807.1, CO567997.1, BP466072.1, CB706441.1 and BP483385.1. On Nov 25, 2008 this sequence version replaced NM_001109976.1. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGCGC AGAGGAGGAG CCTGCTCCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001103446.1 |
CDS | 15..1523 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGCGGCGC AGAGGAGGAG CCTGCTCCAG AGTGAGCAGC AGCCAAGCTG GACAGATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Global genetic analysis in mice unveils central role for cilia in congenital heart disease. |
Immunolocalization of TAK1, TAB1, and p38 in the developing rat molar. |
TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. |
Expanding role of ubiquitination in NF-?B signaling. |
Magnesium Lithospermate B Protects Cardiomyocytes from Ischemic Injury Via Inhibition of TAB1-p38 Apoptosis Signaling. |