Gene Symbol | Tymp |
Entrez Gene ID | 315219 |
Full Name | thymidine phosphorylase |
Synonyms | Ecgf1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Tymp cDNA ORF clone
gRNAs
Gene Symbol | Tymp |
Entrez Gene ID | 315219 |
Full Name | thymidine phosphorylase |
Synonyms | Ecgf1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_008765730.2 | XP_008763952.1 | thymidine phosphorylase isoform X1 |
XM_008765734.2 | XP_008763956.1 | thymidine phosphorylase isoform X5 |
XM_017594882.1 | XP_017450371.1 | thymidine phosphorylase isoform X2 |
XM_006242209.3 | XP_006242271.1 | thymidine phosphorylase isoform X3 |
XM_017594883.1 | XP_017450372.1 | thymidine phosphorylase isoform X4 |
XM_017594884.1 | XP_017450373.1 | thymidine phosphorylase isoform X5 |
NM_001012122.1 | NP_001012122.1 | thymidine phosphorylase |
Antiangiogenic and antitumor activity of 6-(2-aminoethyl)amino-5-chlorouracil, a novel small-molecule inhibitor of thymidine phosphorylase, in combination with the vascular endothelial growth factor-trap.
Lu H, Klein RS, Schwartz EL
Clinical cancer research : an official journal of the American Association for Cancer Research15(16)5136-44(2009 Aug)
Prognostic value of thymidine phosphorylase expression for pancreatic cancer.
Hong SP, Shin SK, Bang S, Park SW, Chung JB, Lee WJ, Song SY
Hepato-gastroenterology56(93)1178-82(2009 Jul-Aug)
Role of tumor angiogenesis in gallbladder carcinoma: with special reference to thymidine phosphorylase.
Harino Y, Imura S, Kanemura H, Morine Y, Fujii M, Ikegami T, Uehara H, Shimada M
International journal of clinical oncology13(5)452-7(2008 Oct)
Thymidine phosphorylase expression is associated with time to progression in patients receiving low-dose, docetaxel-modulated capecitabine for metastatic breast cancer.
Puglisi F, Cardellino GG, Crivellari D, Di Loreto C, Magri MD, Minisini AM, Mansutti M, Andreetta C, Russo S, Lombardi D, Perin T, Damante G, Veronesi A
Annals of oncology : official journal of the European Society for Medical Oncology19(9)1541-6(2008 Sep)
A role of thymidine phosphorylase and P53 tissue protein expression in biology of endometrial cancer.
Mazurek A, Ku? P, Mazurek-Wado?kowska E, Lauda?ski T
Neoplasma55(3)261-5(2008)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The PyNpase levels in rat bladder tissue were significantly higher in the BBN-treatment groups than in those in the control group, only during the early carcinogenic stage
Title: Tissue levels of pyrimidine nucleoside phosphorylase activity in human and rodent bladder cancer and normal bladder tissue.
The following Tymp gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tymp cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13078 | |
Clone ID Related Accession (Same CDS sequence) | NM_001012122.1 | |
Accession Version | NM_001012122.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-14 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC089830.1. On Feb 11, 2005 this sequence version replaced XM_235562.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC089830.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01906356, SAMN01906357 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001012122.1 |
CDS | 63..1493 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47400 | |
Clone ID Related Accession (Same CDS sequence) | XM_008765734.2 , XM_017594884.1 | |
Accession Version | XM_008765734.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765734.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGCTAC TGGCTCTAGG GCCCAAAGCT TGGCCCAAGC TCTCTCAGTT CAAACCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008763956.1 |
CDS | 240..1016 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATGCTAC TGGCTCTAGG GCCCAAAGCT TGGCCCAAGC TCTCTCAGTT CAAACCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47400 | |
Clone ID Related Accession (Same CDS sequence) | XM_008765734.2 , XM_017594884.1 | |
Accession Version | XM_017594884.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 777bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase isoform X5 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGCTAC TGGCTCTAGG GCCCAAAGCT TGGCCCAAGC TCTCTCAGTT CAAACCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017450373.1 |
CDS | 1173..1949 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGATGCTAC TGGCTCTAGG GCCCAAAGCT TGGCCCAAGC TCTCTCAGTT CAAACCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa30672 | |
Clone ID Related Accession (Same CDS sequence) | XM_017594882.1 | |
Accession Version | XM_017594882.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2280bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017450371.1 |
CDS | 388..2667 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa30673 | |
Clone ID Related Accession (Same CDS sequence) | XM_006242209.3 | |
Accession Version | XM_006242209.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2277bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006242209.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006242271.1 |
CDS | 161..2437 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa30674 | |
Clone ID Related Accession (Same CDS sequence) | XM_017594883.1 | |
Accession Version | XM_017594883.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017450372.1 |
CDS | 548..2821 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa47398 | |
Clone ID Related Accession (Same CDS sequence) | XM_008765730.2 | |
Accession Version | XM_008765730.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2283bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | thymidine phosphorylase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008765730.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008763952.1 |
CDS | 161..2443 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCTC CAGGGACACC ACCTCCCTTG GCCCCAGAGA CAGCTGGTGC CGACTCGGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Antiangiogenic and antitumor activity of 6-(2-aminoethyl)amino-5-chlorouracil, a novel small-molecule inhibitor of thymidine phosphorylase, in combination with the vascular endothelial growth factor-trap. |
Prognostic value of thymidine phosphorylase expression for pancreatic cancer. |
Role of tumor angiogenesis in gallbladder carcinoma: with special reference to thymidine phosphorylase. |
Thymidine phosphorylase expression is associated with time to progression in patients receiving low-dose, docetaxel-modulated capecitabine for metastatic breast cancer. |
A role of thymidine phosphorylase and P53 tissue protein expression in biology of endometrial cancer. |