Sema7a cDNA ORF clone, Rattus norvegicus(Norway rat)
| Gene Symbol | Sema7a |
| Entrez Gene ID | 315711 |
| Full Name | semaphorin 7A (John Milton Hagen blood group) |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001108153.1 | NP_001101623.1 | semaphorin-7A precursor |
| XM_017595653.1 | XP_017451142.1 | semaphorin-7A isoform X1 |
| Bos taurus (cattle) | SEMA7A | NP_001193114.1 |
| Homo sapiens (human) | SEMA7A | NP_003603.1 |
| Gallus gallus (chicken) | SEMA7A | NP_001186678.1 |
| Danio rerio (zebrafish) | sema7a | NP_001108357.1 |
| SEMA7A | XP_001099042.1 | |
| Canis lupus familiaris (dog) | SEMA7A | XP_005638673.1 |
| Rattus norvegicus (Norway rat) | Sema7a | NP_001101623.1 |
| Pan troglodytes (chimpanzee) | SEMA7A | XP_523219.2 |
| Mus musculus (house mouse) | Sema7a | NP_035482.1 |
| Xenopus tropicalis (tropical clawed frog) | sema7a | XP_002937527.2 |
Related articles in PubMed
Endothelial semaphorin 7A promotes seawater aspiration-induced acute lung injury through plexin C1 and ?1 integrin.
Zhang M, Yan X, Liu W, Sun R, Xie Y, Jin F
Molecular medicine reports16(4)4215-4221(2017 Oct)
Axon guidance molecule expression after cell therapy in a mouse model of Parkinson's disease.
Kalaani J, Roche J, Hamade E, Badran B, Jaber M, Gaillard A, Prestoz L
Restorative neurology and neuroscience34(6)877-895(2016 Nov)
Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence.
Parkash J, Messina A, Langlet F, Cimino I, Loyens A, Mazur D, Gallet S, Balland E, Malone SA, Pralong F, Cagnoni G, Schellino R, De Marchis S, Mazzone M, Pasterkamp RJ, Tamagnone L, Prevot V, Giacobini P
Nature communications66385(2015 Feb)
Endothelial Semaphorin 7A promotes inflammation in seawater aspiration-induced acute lung injury.
Zhang M, Wang L, Dong M, Li Z, Jin F
International journal of molecular sciences15(11)19650-61(2014 Oct)
Maturation of cortical circuits requires Semaphorin 7A.
Carcea I, Patil SB, Robison AJ, Mesias R, Huntsman MM, Froemke RC, Buxbaum JD, Huntley GW, Benson DL
Proceedings of the National Academy of Sciences of the United States of America111(38)13978-83(2014 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study shown that mrna of expression of semaphorin 7A after cell therapy in a mouse model of Parkinson's disease.
Title: Axon guidance molecule expression after cell therapy in a mouse model of Parkinson's disease.
Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence.
Title: Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence.
SEMA7A is critical in the development of lung inflammation and pulmonary edema in seawater aspiration-induced ALI, and may be a therapeutic target for this disease.
Title: Endothelial Semaphorin 7A promotes inflammation in seawater aspiration-induced acute lung injury.
These data identify Sema7A as a regulator of thalamocortical and local circuit development in layer 4 and provide a molecular handle that can be used to explore the coordinated generation of excitatory and inhibitory cortical circuits.
Title: Maturation of cortical circuits requires Semaphorin 7A.
Sema7A acts as a positive regulator for thalamocortical axon branching and/or pre-synaptic puncta formation
Title: The action of Semaphorin7A on thalamocortical axon branching.
The following Sema7a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sema7a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa47455 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017595653.1 | |
| Accession Version | XM_017595653.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1527bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | semaphorin-7A isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTCACTTG GTGAGATGAA AGGCTATGCC CCCTTCAGCC CGGATGAGAA CTCCCTGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017451142.1 |
| CDS | 432..1958 |
| Translation |
Target ORF information:
Target ORF information:
|
 XM_017595653.1 |
ORF Insert Sequence:
1 | ATGTCACTTG GTGAGATGAA AGGCTATGCC CCCTTCAGCC CGGATGAGAA CTCCCTGGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa06765 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001108153.1 | |
| Accession Version | NM_001108153.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2001bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-20 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | semaphorin-7A precursor | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473975.1. On or before Oct 22, 2008 this sequence version replaced XM_001072477.1, XM_243863.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGACGCCTC CTCCTCCCGG ACGTGCCGCC CCCAGCGCAC CGCGCGCCCG CGTCCTCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001101623.1 |
| CDS | 6..2006 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001108153.1 |
ORF Insert Sequence:
1 | ATGACGCCTC CTCCTCCCGG ACGTGCCGCC CCCAGCGCAC CGCGCGCCCG CGTCCTCAGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Endothelial semaphorin 7A promotes seawater aspiration-induced acute lung injury through plexin C1 and ?1 integrin. |
|
Axon guidance molecule expression after cell therapy in a mouse model of Parkinson's disease. |
|
Semaphorin7A regulates neuroglial plasticity in the adult hypothalamic median eminence. |
|
Endothelial Semaphorin 7A promotes inflammation in seawater aspiration-induced acute lung injury. |
|
Maturation of cortical circuits requires Semaphorin 7A. |