Gene Symbol | Ube2e2 |
Entrez Gene ID | 361013 |
Full Name | ubiquitin-conjugating enzyme E2E 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ube2e2 cDNA ORF clone
Gene Symbol | Ube2e2 |
Entrez Gene ID | 361013 |
Full Name | ubiquitin-conjugating enzyme E2E 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006251699.3 | XP_006251761.3 | ubiquitin-conjugating enzyme E2 E2 isoform X1 |
NM_001108371.1 | NP_001101841.1 | ubiquitin-conjugating enzyme E2 E2 |
Mus musculus (house mouse) | Ube2e2 | NP_659088.1 |
Rattus norvegicus (Norway rat) | Ube2e2 | NP_001101841.1 |
Drosophila melanogaster (fruit fly) | UbcD2 | NP_001260362.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007952 | XP_317521.4 |
Homo sapiens (human) | UBE2E2 | NP_689866.1 |
UBE2E2 | XP_001089978.1 | |
Bos taurus (cattle) | UBE2E2 | NP_001178119.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012754 | XP_306962.4 |
Xenopus tropicalis (tropical clawed frog) | ube2e2 | NP_001119983.1 |
Pan troglodytes (chimpanzee) | UBE2E2 | XP_003309701.1 |
Canis lupus familiaris (dog) | UBE2E2 | XP_005634421.1 |
Gallus gallus (chicken) | UBE2E2 | XP_004939459.1 |
Danio rerio (zebrafish) | ube2e2 | NP_001003494.1 |
Identification of epigenetically downregulated Tmem70 and Ube2e2 in rat liver after 28-day treatment with hepatocarcinogenic thioacetamide showing gene product downregulation in hepatocellular preneoplastic and neoplastic lesions produced by tumor promotion.
Mizukami S, Yafune A, Watanabe Y, Nakajima K, Jin M, Yoshida T, Shibutani M
Toxicology letters26613-22(2017 Jan)
Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex.
Shibata E, Abbas T, Huang X, Wohlschlegel JA, Dutta A
Molecular and cellular biology31(15)3136-45(2011 Aug)
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.
David Y, Ziv T, Admon A, Navon A
The Journal of biological chemistry285(12)8595-604(2010 Mar)
Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme.
Takeuchi T, Iwahara S, Saeki Y, Sasajima H, Yokosawa H
Journal of biochemistry138(6)711-9(2005 Dec)
cDNA cloning, characterization, and chromosome mapping of UBE2E2 encoding a human ubiquitin-conjugating E2 enzyme.
Kimura M, Hattori T, Matsuda Y, Yoshioka T, Sumi N, Umeda Y, Nakashima S, Okano Y
Cytogenetics and cell genetics78(2)107-11(1997)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The effect of thioacetamide on neoplastic liver changes and hypermethylation and downregulation of proteins, especially Tmem70 and Ube2e2, are reported.
Title: Identification of epigenetically downregulated Tmem70 and Ube2e2 in rat liver after 28-day treatment with hepatocarcinogenic thioacetamide showing gene product downregulation in hepatocellular preneoplastic and neoplastic lesions produced by tumor promotion.
The following Ube2e2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ube2e2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa11708 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108371.1 | |
Accession Version | NM_001108371.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 555bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ubiquitin-conjugating enzyme E2 E2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474010.1. On or before Oct 4, 2007 this sequence version replaced XM_341288.3, XM_001067024.1. ##Evidence-Data-START## Transcript exon combination :: CB608770.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMEA2689598 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCACCG AGGCACAGAG AGTTGATGAC AGTCCAAGCA CTAGCGGAGG AAGTTCTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001101841.1 |
CDS | 14..568 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001108371.1 |
1 | ATGTCCACCG AGGCACAGAG AGTTGATGAC AGTCCAAGCA CTAGCGGAGG AAGTTCTGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa58611 | |
Clone ID Related Accession (Same CDS sequence) | XM_006251699.3 | |
Accession Version | XM_006251699.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 633bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ubiquitin-conjugating enzyme E2 E2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005114.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251699.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATTCT TTAACCCAGG ATCTAAGATG TCCACCGAGG CACAGAGAGT TGATGACAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006251761.3 |
CDS | 24..656 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006251699.3 |
1 | ATGTCATTCT TTAACCCAGG ATCTAAGATG TCCACCGAGG CACAGAGAGT TGATGACAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Identification of epigenetically downregulated Tmem70 and Ube2e2 in rat liver after 28-day treatment with hepatocarcinogenic thioacetamide showing gene product downregulation in hepatocellular preneoplastic and neoplastic lesions produced by tumor promotion. |
Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex. |
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. |
Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme. |
cDNA cloning, characterization, and chromosome mapping of UBE2E2 encoding a human ubiquitin-conjugating E2 enzyme. |