Gene Symbol | RGD1307443 |
Entrez Gene ID | 361244 |
Full Name | similar to mKIAA0319 protein |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » RGD1307443 cDNA ORF clone
gRNAs
Gene Symbol | RGD1307443 |
Entrez Gene ID | 361244 |
Full Name | similar to mKIAA0319 protein |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001197023.1 | NP_001183952.1 | dyslexia-associated protein KIAA0319 homolog precursor |
XM_006253936.3 | XP_006253998.1 | dyslexia-associated protein KIAA0319 homolog isoform X2 |
XM_017600604.1 | XP_017456093.1 | dyslexia-associated protein KIAA0319 homolog isoform X1 |
Pan troglodytes (chimpanzee) | KIAA0319 | XP_003311087.2 |
Mus musculus (house mouse) | D130043K22Rik | NP_001074520.1 |
Canis lupus familiaris (dog) | KIAA0319 | XP_535903.3 |
Rattus norvegicus (Norway rat) | RGD1307443 | NP_001183952.1 |
Gallus gallus (chicken) | KIAA0319 | XP_426033.4 |
Danio rerio (zebrafish) | LOC794624 | XP_005158358.1 |
Bos taurus (cattle) | KIAA0319 | XP_005223874.1 |
Homo sapiens (human) | KIAA0319 | NP_001161846.1 |
Drosophila melanogaster (fruit fly) | CG7565 | NP_648171.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008639 | XP_314736.4 |
Xenopus tropicalis (tropical clawed frog) | kiaa0319 | XP_002936492.2 |
Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing.
Guidi LG, Mattley J, Martinez-Garay I, Monaco AP, Linden JF, Velayos-Baeza A, Moln?r Z
Cerebral cortex (New York, N.Y. : 1991)27(12)5831-5845(2017 Dec)
Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice.
Martinez-Garay I, Guidi LG, Holloway ZG, Bailey MA, Lyngholm D, Schneider T, Donnison T, Butt SJ, Monaco AP, Moln?r Z, Velayos-Baeza A
Brain structure & function222(3)1367-1384(2017 04)
Knockdown of the dyslexia-associated gene Kiaa0319 impairs temporal responses to speech stimuli in rat primary auditory cortex.
Centanni TM, Booker AB, Sloan AM, Chen F, Maher BJ, Carraway RS, Khodaparast N, Rennaker R, LoTurco JJ, Kilgard MP
Cerebral cortex (New York, N.Y. : 1991)24(7)1753-66(2014 Jul)
Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown.
Centanni TM, Chen F, Booker AM, Engineer CT, Sloan AM, Rennaker RL, LoTurco JJ, Kilgard MP
PloS one9(5)e98439(2014)
The effects of Kiaa0319 knockdown on cortical and subcortical anatomy in male rats.
Szalkowski CE, Fiondella CF, Truong DT, Rosen GD, LoTurco JJ, Fitch RH
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience31(2)116-22(2013 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results provide the first evidence that decreased expression of the dyslexia-associated gene Kiaa0319 can alter cortical responses and impair phoneme processing in auditory cortex.
Title: Knockdown of the dyslexia-associated gene Kiaa0319 impairs temporal responses to speech stimuli in rat primary auditory cortex.
Reduced expression of the dyslexia-associated gene KIAA0319 can cause phoneme processing impairments similar to those seen in dyslexia.
Title: Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown.
These results suggest that Kiaa0319 has a specific involvement in neural systems important for temporal processing.
Title: The effects of Kiaa0319 knockdown on cortical and subcortical anatomy in male rats.
The following RGD1307443 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RGD1307443 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13327 | |
Clone ID Related Accession (Same CDS sequence) | NM_001197023.1 , XM_017600604.1 | |
Accession Version | NM_001197023.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | dyslexia-associated protein KIAA0319 homolog precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07027719.1 and AABR07027718.1. On or before Oct 2, 2010 this sequence version replaced XM_001070349.2, XM_341527.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGTGTCCC CACCAGGAGT ACTGTCTTCC TTGCTGCTGC TGGCAGCCAT GGCAGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001183952.1 |
CDS | 245..3490 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGTGTCCC CACCAGGAGT ACTGTCTTCC TTGCTGCTGC TGGCAGCCAT GGCAGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa13327 | |
Clone ID Related Accession (Same CDS sequence) | NM_001197023.1 , XM_017600604.1 | |
Accession Version | XM_017600604.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3246bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | dyslexia-associated protein KIAA0319 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGTCCC CACCAGGAGT ACTGTCTTCC TTGCTGCTGC TGGCAGCCAT GGCAGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017456093.1 |
CDS | 740..3985 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTGTCCC CACCAGGAGT ACTGTCTTCC TTGCTGCTGC TGGCAGCCAT GGCAGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa37880 | |
Clone ID Related Accession (Same CDS sequence) | XM_006253936.3 | |
Accession Version | XM_006253936.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3123bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | dyslexia-associated protein KIAA0319 homolog isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005116.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006253936.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGTCCC CACCAGGAGT ACTGTCTTCC TTGCTGCTGC TGGCAGCCAT GGCAGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006253998.1 |
CDS | 593..3715 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTGTCCC CACCAGGAGT ACTGTCTTCC TTGCTGCTGC TGGCAGCCAT GGCAGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing. |
Normal radial migration and lamination are maintained in dyslexia-susceptibility candidate gene homolog Kiaa0319 knockout mice. |
Knockdown of the dyslexia-associated gene Kiaa0319 impairs temporal responses to speech stimuli in rat primary auditory cortex. |
Speech sound processing deficits and training-induced neural plasticity in rats with dyslexia gene knockdown. |
The effects of Kiaa0319 knockdown on cortical and subcortical anatomy in male rats. |