Gene Symbol | Fech |
Entrez Gene ID | 361338 |
Full Name | ferrochelatase |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Fech cDNA ORF clone
gRNAs
Gene Symbol | Fech |
Entrez Gene ID | 361338 |
Full Name | ferrochelatase |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006254850.3 | XP_006254912.1 | ferrochelatase, mitochondrial isoform X1 |
NM_001108434.1 | NP_001101904.1 | ferrochelatase, mitochondrial |
Gallus gallus (chicken) | FECH | NP_989527.1 |
Kluyveromyces lactis | KLLA0F20141g | XP_455984.1 |
Eremothecium gossypii | AGOS_AGR272W | NP_986938.1 |
Schizosaccharomyces pombe (fission yeast) | hem15 | NP_587720.1 |
Xenopus tropicalis (tropical clawed frog) | fech | XP_002934473.1 |
FECH | XP_002800996.1 | |
Canis lupus familiaris (dog) | FECH | XP_852936.1 |
Saccharomyces cerevisiae (baker's yeast) | HEM15 | NP_014819.3 |
Neurospora crassa | NCU08291 | XP_962504.1 |
Oryza sativa (rice) | Os05g0361200 | NP_001055309.1 |
Homo sapiens (human) | FECH | NP_000131.2 |
Pan troglodytes (chimpanzee) | FECH | NP_001033101.1 |
Mus musculus (house mouse) | Fech | NP_032024.2 |
Rattus norvegicus (Norway rat) | Fech | NP_001101904.1 |
Danio rerio (zebrafish) | fech | NP_571706.1 |
Drosophila melanogaster (fruit fly) | ferrochelatase | NP_524613.1 |
Arabidopsis thaliana (thale cress) | FC2 | NP_001189639.1 |
Bos taurus (cattle) | FECH | NP_776479.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003719 | XP_310249.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_15723 | XP_003714486.1 |
Erythropoietic protoporphyria a clinical and molecular study from Lebanon: Ferrochelatase a potential tumor suppressor gene in colon cancer.
Kadara H, Nemer G, Safi R, Rebeiz N, Daou L, Delbani D, Btadini W, Abbas O, Tofaili M, Bitar F, Kibbi AG, Shimomura Y, Kurban M
Clinical genetics92(5)495-502(2017 Nov)
Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors.
Barupala DP, Dzul SP, Riggs-Gelasco PJ, Stemmler TL
Archives of biochemistry and biophysics59260-75(2016 Feb)
Incomplete erythropoietic protoporphyria caused by a splice site modulator homozygous IVS3-48C polymorphism in the ferrochelatase gene.
Mizawa M, Makino T, Nakano H, Sawamura D, Shimizu T
The British journal of dermatology174(1)172-5(2016 Jan)
A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease.
Farrag MS, Ku?erov? J, ?lachtov? L, ?eda O, ?perl J, Mart?sek P
Folia biologica61(6)227-32(2015)
HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.
White C, Yuan X, Schmidt PJ, Bresciani E, Samuel TK, Campagna D, Hall C, Bishop K, Calicchio ML, Lapierre A, Ward DM, Liu P, Fleming MD, Hamza I
Cell metabolism17(2)261-70(2013 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Fech gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Fech cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa07316 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108434.1 | |
Accession Version | NM_001108434.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ferrochelatase, mitochondrial | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473971.1. On or before Oct 4, 2007 this sequence version replaced XM_001060349.1, XM_341622.3, XM_001060280.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01906349 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGCTTTCGG CCGGCGCCAA CATGGCTGCG GCCCTGCGGG CTGCGGGCGC TCTGTTCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001101904.1 |
CDS | 98..1366 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTTTCGG CCGGCGCCAA CATGGCTGCG GCCCTGCGGG CTGCGGGCGC TCTGTTCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa38451 | |
Clone ID Related Accession (Same CDS sequence) | XM_006254850.3 | |
Accession Version | XM_006254850.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1362bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ferrochelatase, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005117.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006254850.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGACCTG AGCCAAGGCT TGGCGAGAAG ATAAGGGTAG CTTCTAAAAA GATCAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006254912.1 |
CDS | 2261..3622 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGACCTG AGCCAAGGCT TGGCGAGAAG ATAAGGGTAG CTTCTAAAAA GATCAAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Erythropoietic protoporphyria a clinical and molecular study from Lebanon: Ferrochelatase a potential tumor suppressor gene in colon cancer. |
Synthesis, delivery and regulation of eukaryotic heme and Fe-S cluster cofactors. |
Incomplete erythropoietic protoporphyria caused by a splice site modulator homozygous IVS3-48C polymorphism in the ferrochelatase gene. |
A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease. |
HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis. |