Gene Symbol | Ahcyl1 |
Entrez Gene ID | 362013 |
Full Name | adenosylhomocysteinase-like 1 |
Synonyms | IRBIT |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ahcyl1 cDNA ORF clone
Gene Symbol | Ahcyl1 |
Entrez Gene ID | 362013 |
Full Name | adenosylhomocysteinase-like 1 |
Synonyms | IRBIT |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001108561.1 | NP_001102031.1 | S-adenosylhomocysteine hydrolase-like protein 1 |
XM_006233166.3 | XP_006233228.1 | adenosylhomocysteinase 2 isoform X2 |
XM_006233165.1 | XP_006233227.1 | adenosylhomocysteinase 2 isoform X1 |
XM_008761405.2 | XP_008759627.1 | adenosylhomocysteinase 2 isoform X2 |
XM_006233167.1 | XP_006233229.1 | adenosylhomocysteinase 2 isoform X3 |
Homo sapiens (human) | AHCYL1 | NP_006612.2 |
Mus musculus (house mouse) | Ahcyl1 | NP_663517.2 |
Canis lupus familiaris (dog) | AHCYL1 | XP_005621863.1 |
Drosophila melanogaster (fruit fly) | CG9977 | NP_647746.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000792 | XP_311334.4 |
Danio rerio (zebrafish) | ahcyl1 | NP_958450.1 |
Pan troglodytes (chimpanzee) | AHCYL1 | XP_514386.3 |
AHCYL1 | XP_001098170.1 | |
Rattus norvegicus (Norway rat) | Ahcyl1 | NP_001102031.1 |
Gallus gallus (chicken) | AHCYL1 | NP_001026084.1 |
Bos taurus (cattle) | AHCYL1 | NP_001094522.2 |
The IP3 R Binding Protein Released With Inositol 1,4,5-Trisphosphate Is Expressed in Rodent Reproductive Tissue and Spermatozoa.
Borth H, Weber N, Meyer D, Wartenberg A, Arlt E, Zierler S, Breit A, Wennemuth G, Gudermann T, Boekhoff I
Journal of cellular physiology231(5)1114-29(2016 May)
IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type I? and II? through Conserved Catalytic Aspartate Residues.
Ando H, Hirose M, Gainche L, Kawaai K, Bonneau B, Ijuin T, Itoh T, Takenawa T, Mikoshiba K
PloS one10(10)e0141569(2015)
Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.
Park S, Shcheynikov N, Hong JH, Zheng C, Suh SH, Kawaai K, Ando H, Mizutani A, Abe T, Kiyonari H, Seki G, Yule D, Mikoshiba K, Muallem S
Gastroenterology145(1)232-41(2013 Jul)
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.
Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W
Immunology and cell biology88(8)851-6(2010 Nov-Dec)
Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II.
He P, Klein J, Yun CC
The Journal of biological chemistry285(36)27869-78(2010 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The present study documents that IRBIT is expressed in Leydig and Sertoli cells.
Title: The IP3 R Binding Protein Released With Inositol 1,4,5-Trisphosphate Is Expressed in Rodent Reproductive Tissue and Spermatozoa.
IRBIT forms signaling complexes with PIPKIalpha and NBCe1-B, whose activity is regulated by PI(4,5)P2.
Title: IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type I? and II? through Conserved Catalytic Aspartate Residues.
IRBIT is critically involved in mediating activation of NHE3 by ANG II via a Ca(2+)/calmodulin-dependent protein kinases II-dependent pathway.
Title: Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II.
The following Ahcyl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ahcyl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13919 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108561.1 | |
Accession Version | NM_001108561.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | S-adenosylhomocysteine hydrolase-like protein 1 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473952.1. On or before Oct 4, 2007 this sequence version replaced XM_342312.3, XM_001068488.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102031.1 |
CDS | 136..1563 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001108561.1 |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa25184 | |
Clone ID Related Accession (Same CDS sequence) | XM_006233166.3 , XM_006233165.1 , XM_008761405.2 | |
Accession Version | XM_006233166.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | adenosylhomocysteinase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006233166.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006233228.1 |
CDS | 345..1796 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006233166.3 |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa25184 | |
Clone ID Related Accession (Same CDS sequence) | XM_006233166.3 , XM_006233165.1 , XM_008761405.2 | |
Accession Version | XM_006233165.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | adenosylhomocysteinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006233227.1 |
CDS | 20..1471 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006233165.1 |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa25184 | |
Clone ID Related Accession (Same CDS sequence) | XM_006233166.3 , XM_006233165.1 , XM_008761405.2 | |
Accession Version | XM_008761405.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1452bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | adenosylhomocysteinase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008761405.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008759627.1 |
CDS | 360..1811 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008761405.2 |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa25185 | |
Clone ID Related Accession (Same CDS sequence) | XM_006233167.1 | |
Accession Version | XM_006233167.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | adenosylhomocysteinase 2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006233229.1 |
CDS | 20..1468 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006233167.1 |
1 | ATGCAAGAGT TCACCAAATT CCCTACTAAG ACTGGCCGGA GATCCTTGTC TCGCTCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The IP3 R Binding Protein Released With Inositol 1,4,5-Trisphosphate Is Expressed in Rodent Reproductive Tissue and Spermatozoa. |
IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type I? and II? through Conserved Catalytic Aspartate Residues. |
Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice. |
MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. |
Activation of Na+/H+ exchanger NHE3 by angiotensin II is mediated by inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3 (IRBIT) and Ca2+/calmodulin-dependent protein kinase II. |