Xrn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Xrn2
Entrez Gene ID	362229
Full Name	5'-3' exoribonuclease 2
General protein information	Preferred Names 5'-3' exoribonuclease 2 Names 5'-3' exoribonuclease 2
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 3 Map Location: 3q41

mRNA and Protein(s)

mRNA Protein Name

XM_006235156.3 XP_006235218.1 5'-3' exoribonuclease 2

NM_001108596.2 NP_001102066.2 5'-3' exoribonuclease 2

XM_017602625.1 XP_017458114.1 5'-3' exoribonuclease 2
Pathways from BioSystems

mRNA	Protein	Name
XM_006235156.3	XP_006235218.1	5'-3' exoribonuclease 2
NM_001108596.2	NP_001102066.2	5'-3' exoribonuclease 2
XM_017602625.1	XP_017458114.1	5'-3' exoribonuclease 2

Homologies

Eremothecium gossypii	AGOS_AGR303W	NP_986969.2
Pan troglodytes (chimpanzee)	XRN2	XP_514546.2
Canis lupus familiaris (dog)	XRN2	XP_534324.2
Rattus norvegicus (Norway rat)	Xrn2	NP_001102066.1
Drosophila melanogaster (fruit fly)	Rat1	NP_001260166.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004090	XP_309641.5
Caenorhabditis elegans (roundworm)	xrn-2	NP_496958.2
Saccharomyces cerevisiae (baker's yeast)	RAT1	NP_014691.1
Xenopus tropicalis (tropical clawed frog)	xrn2	XP_002939479.1
Homo sapiens (human)	XRN2	NP_036387.2
Bos taurus (cattle)	XRN2	NP_001179401.1
Mus musculus (house mouse)	Xrn2	NP_036047.2
Schizosaccharomyces pombe (fission yeast)	dhp1	NP_594155.1
Neurospora crassa	NCU01643	XP_956265.1
	XRN2	XP_001094734.2
Gallus gallus (chicken)	XRN2	NP_001026204.1
Danio rerio (zebrafish)	xrn2	NP_001001944.2
Magnaporthe oryzae (rice blast fungus)	MGG_11426	XP_003717803.1
Kluyveromyces lactis	KLLA0F07469g	XP_455419.1
Arabidopsis thaliana (thale cress)	XRN3	NP_565114.1
Oryza sativa (rice)	Os01g0872700	NP_001044947.1

Gene Ontology
Bibliography

Related articles in PubMed

Pilocarpine-induced seizures trigger differential regulation of microRNA-stability related genes in rat hippocampal neurons.
Kinjo ER, Higa GS, Santos BA, de Sousa E, Damico MV, Walter LT, Morya E, Valle AC, Britto LR, Kihara AH
Scientific reports620969(2016 Feb)

The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.
Sloan KE, Bohnsack MT, Schneider C, Watkins NJ
RNA (New York, N.Y.)20(4)540-50(2014 Apr)

Gene expression signatures of primary and metastatic uterine leiomyosarcoma.
Davidson B, Abeler VM, F?rsund M, Holth A, Yang Y, Kobayashi Y, Chen L, Kristensen GB, Shih IeM, Wang TL
Human pathology45(4)691-700(2014 Apr)

A possible new mechanism for the control of miRNA expression in neurons.
Kinjo ER, Higa GS, de Sousa E, Casado OA, Damico MV, Britto LR, Kihara AH
Experimental neurology248546-58(2013 Oct)

Developmental and functional expression of miRNA-stability related genes in the nervous system.
de Sousa ?, Walter LT, Higa GS, Casado OA, Kihara AH
PloS one8(5)e56908(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

XRN2 and PAPD4 and are highly expressed in the retina and have distinct gene expression profiles during development.
Title: Developmental and functional expression of miRNA-stability related genes in the nervous system.

The following Xrn2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Xrn2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa26464	XM_006235156.3 Latest version!	Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa26464	XM_017602625.1 Latest version!	Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa26464	NM_001108596.2 Latest version!	Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Xrn2 ( XM_006235156.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006235218.1 Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.

Price & Availability↑

CloneID	ORa26464
Clone ID Related Accession (Same CDS sequence)	XM_006235156.3 , NM_001108596.2 , XM_017602625.1
Accession Version	XM_006235156.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2856bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	5'-3' exoribonuclease 2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006235156.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CGGCGTTCTT CCGCTGGCTC AGCCGCAAGT ACCCGTCCAT CATTGTCAAT 
TGCGTGGAGG AGAAGCCAAA AGAATGCAAT GGTGTGAAGA TTCCAGTTGA TGCCAGTAAA 
CCTAATCCAA ATGATGTGGA GTTTGATAAT CTGTATTTGG ATATGAATGG AATCATCCAT 
CCCTGTACTC ATCCTGAAGA CAAACCAGCA CCAAAAAATG AAGATGAAAT GATGGTTGCA 
ATTTTTGAGT ACATTGACAG ACTTTTCAAT ATTGTAAGAC CAAGAAGACT TCTCTATATG 
GCAATAGATG GAGTGGCACC ACGTGCCAAA ATGAACCAGC AGCGTTCAAG GAGGTTCAGA 
GCATCTAAGG AAGGAATGGA AGCCGCAGTT GAGAAGCAGC GAGTCAGAGA GGAAATACTT 
GCAAAAGGTG GCTTTCTTCC TCCAGAAGAA ATAAAAGAAA GATTTGACAG CAACTGTATT 
ACACCAGGAA CTGAGTTCAT GGACAATCTT GCTAAATGCC TTCGCTATTA CATAGCTGAT 
CGTTTAAATA ATGACCCCGG GTGGAAAAAT TTGACAGTTA TATTATCTGA CGCTAGTGCG 
CCTGGTGAAG GAGAACACAA AATCATGGAT TACATTAGAA GACAAAGAGC CCAGCCTAAC 
CATGACCCAA ATACTCATCA TTGTTTATGT GGAGCTGATG CTGATCTCAT TATGCTTGGT 
CTTGCTACAC ATGAACCTAA CTTCACCATA ATCAGAGAAG AATTCAAACC AAATAAACCT 
AAACCATGTG CTCTTTGTAA TCAGTTTGGA CACGAGGTCA AGGACTGTGA AGGTTTGCCC 
AGAGAAAAGA AGGGGAAGCA TGATGAACTT GCAGATAGTC TTCCTTGTGC AGAAGGGGAG 
TTCATCTTCC TTCGGCTGAA TGTCCTTCGA GAGTATCTGG AACGAGAGCT CACCATGGCC 
AGCTTACCGT TCCCATTTGA TGTGGAGAGG AGCATCGATG ACTGGGTGTT CATGTGCTTC 
TTTGTGGGGA ATGATTTCCT TCCTCACTTG CCGTCACTAG AGATTAGGGA AGGTGCAATT 
GATCGTTTGG TTAACATATA CAAAAACGTG GTACACAAAA CTGGGGGTTA CCTTACAGAA 
AGTGGTTATG TCAATCTACA AAGAGTACAG ATGATCATGT TAGCAGTTGG TGAAGTTGAG 
GATAGCATTT TTAAAAAGAG AAAAGATGAT GAGGACAGTT TTAGAAGACG ACAGAAAGAA 
AAAAGAAAGA GGATGAAGAG AGATCAACCA GCTTTTACTC CTAGTGGAAT ATTAACACCT 
TACGCTTTGG GTTCAAGAAA TTCTCCAGGT TGTCAAGTAG CCAGTAATCC AAGACAAGCC 
GCCTATGAAA TGAGGATGCA GAGTAACTCT AGTCCTTCAA TATCCCCTAA TACAAGTTTT 
GCATCTGATG GCTCCCCATC TCCACTAGGA GGACTTAAGA GAAAAGCAGA AGATAGTGAT 
AGTGAGCCAG AGCCAGAGGA TAACGTCAGG TTATGGGAAG CTGGTTGGAA GCAGCGATAC 
TACAAGAACA AATTTGATGT AGATGCAGCT GATGAGAAAT TCCGACGTAA GGTTGTTCAG 
TCTTATGTTG AAGGATTGTG CTGGGTTCTT CGATATTATT ACCAGGGCTG TGCTTCCTGG 
AAGTGGTATT ACCCATTCCA TTATGCGCCG TTTGCCTCAG ACTTTGAAGG TATTGCAGAC 
ATGCCTTCTG AATTTGAAAA GGGCACAAAA CCGTTTAAAC CACTGGAACA GCTAATGGGG 
GTTTTTCCAG CTGCAAGTGG TAACTTTTTA CCTCCAACAT GGCGGAAGCT CATGAGTGAC 
CCTGATTCTA GTATAATTGA CTTCTATCCT GAAGACTTTG CTATTGATTT GAATGGGAAG 
AAGTATGCAT GGCAAGGTGT TGCTCTGTTG CCATTTGTGG ATGAGCGAAG GCTGCGAGCG 
GCCCTAGAAG AGGTGTACCC AGACCTCACT CCAGAAGAGA ACAGGAGAAA TAGTCTTGGA 
AGTGATGTTT TGTTTGTGGG AAAAGTTCAT CCACTACACG ACTTCATTTT AGAGCTGTAT 
CAGACAGGTT CTACAGAGCC AGTAGATGTG CCGCCTGAGT TGTGTCACGG GATTCAAGGG 
AAGTTTTCTT TGGATGAAGA AGCCATACTT CCAGACCAAA CAGTATGTTC CCCTGTGCCC 
ATGTTACGGG ACTTGACACA GAACACTGCA ATCAGTATTA ATTTTAAAGA TCCACAGTTT 
GCGGAAGATT ATGTTTTTAA AGCTATAATG CTTCCAGGAG CAAGAAAGCC AGCAGCAGTT 
CTGAAACCCG GAGACTGGGA AAAATCCAGC AATGGGCGGC AATGGAAACC CCAGCTTGGC 
TTTAACCGGG ACCGGCGGCC TGTTCACCTG GACCAGGCAG CCTTTAGAAC TTTAGGCCAT 
GTTATACCAA GAGGCTCAGG GACTGGTGTT TACAGCAACA CTGCACCCCC ACCTGCCAAT 
TACCAGGGGA ACGTATACAG GCCACTGCTG AGAGGTCAAG CTCAGATCCC AAAACTAATG 
TCAAATATGA GGCCCCAAGA TAACTGGCGA GGTCCTCCTC CTCTTTTCCA GCAGCAGAGA 
TTTGACAGAA GTGTTGGAGC TGAACCCCTA CTGCCGTGGA ACCGAATGCT CCAAACCCAA 
AATGCAGCCT TTCAGCCAAA TCAGTACCAG ATGCTGGCTG GGCCCGGAGG ATATCCACCC 
AGACGTGATG ACCATCGAGG AGGGCGACAG GGATATCCCA GAGAAGGAAG GAAGTACCCT 
TTGCCACCGC CCTCGGGAAG ATACAGTTGG AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006235218.1
CDS	529..3384
Translation	MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHLPSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPYALGSRNSPGCQVASNPRQAAYEMRMQSNSSPSISPNTSFASDGSPSPLGGLKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGSDVLFVGKVHPLHDFILELYQTGSTEPVDVPPELCHGIQGKFSLDEEAILPDQTVCSPVPMLRDLTQNTAISINFKDPQFAEDYVFKAIMLPGARKPAAVLKPGDWEKSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVIPRGSGTGVYSNTAPPPANYQGNVYRPLLRGQAQIPKLMSNMRPQDNWRGPPPLFQQQRFDRSVGAEPLLPWNRMLQTQNAAFQPNQYQMLAGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN

Target ORF information:

RefSeq Version	XM_006235156.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006235156.3

ORF Insert Sequence:

ATGGGAGTCC CGGCGTTCTT CCGCTGGCTC AGCCGCAAGT ACCCGTCCAT CATTGTCAAT 
TGCGTGGAGG AGAAGCCAAA AGAATGCAAT GGTGTGAAGA TTCCAGTTGA TGCCAGTAAA 
CCTAATCCAA ATGATGTGGA GTTTGATAAT CTGTATTTGG ATATGAATGG AATCATCCAT 
CCCTGTACTC ATCCTGAAGA CAAACCAGCA CCAAAAAATG AAGATGAAAT GATGGTTGCA 
ATTTTTGAGT ACATTGACAG ACTTTTCAAT ATTGTAAGAC CAAGAAGACT TCTCTATATG 
GCAATAGATG GAGTGGCACC ACGTGCCAAA ATGAACCAGC AGCGTTCAAG GAGGTTCAGA 
GCATCTAAGG AAGGAATGGA AGCCGCAGTT GAGAAGCAGC GAGTCAGAGA GGAAATACTT 
GCAAAAGGTG GCTTTCTTCC TCCAGAAGAA ATAAAAGAAA GATTTGACAG CAACTGTATT 
ACACCAGGAA CTGAGTTCAT GGACAATCTT GCTAAATGCC TTCGCTATTA CATAGCTGAT 
CGTTTAAATA ATGACCCCGG GTGGAAAAAT TTGACAGTTA TATTATCTGA CGCTAGTGCG 
CCTGGTGAAG GAGAACACAA AATCATGGAT TACATTAGAA GACAAAGAGC CCAGCCTAAC 
CATGACCCAA ATACTCATCA TTGTTTATGT GGAGCTGATG CTGATCTCAT TATGCTTGGT 
CTTGCTACAC ATGAACCTAA CTTCACCATA ATCAGAGAAG AATTCAAACC AAATAAACCT 
AAACCATGTG CTCTTTGTAA TCAGTTTGGA CACGAGGTCA AGGACTGTGA AGGTTTGCCC 
AGAGAAAAGA AGGGGAAGCA TGATGAACTT GCAGATAGTC TTCCTTGTGC AGAAGGGGAG 
TTCATCTTCC TTCGGCTGAA TGTCCTTCGA GAGTATCTGG AACGAGAGCT CACCATGGCC 
AGCTTACCGT TCCCATTTGA TGTGGAGAGG AGCATCGATG ACTGGGTGTT CATGTGCTTC 
TTTGTGGGGA ATGATTTCCT TCCTCACTTG CCGTCACTAG AGATTAGGGA AGGTGCAATT 
GATCGTTTGG TTAACATATA CAAAAACGTG GTACACAAAA CTGGGGGTTA CCTTACAGAA 
AGTGGTTATG TCAATCTACA AAGAGTACAG ATGATCATGT TAGCAGTTGG TGAAGTTGAG 
GATAGCATTT TTAAAAAGAG AAAAGATGAT GAGGACAGTT TTAGAAGACG ACAGAAAGAA 
AAAAGAAAGA GGATGAAGAG AGATCAACCA GCTTTTACTC CTAGTGGAAT ATTAACACCT 
TACGCTTTGG GTTCAAGAAA TTCTCCAGGT TGTCAAGTAG CCAGTAATCC AAGACAAGCC 
GCCTATGAAA TGAGGATGCA GAGTAACTCT AGTCCTTCAA TATCCCCTAA TACAAGTTTT 
GCATCTGATG GCTCCCCATC TCCACTAGGA GGACTTAAGA GAAAAGCAGA AGATAGTGAT 
AGTGAGCCAG AGCCAGAGGA TAACGTCAGG TTATGGGAAG CTGGTTGGAA GCAGCGATAC 
TACAAGAACA AATTTGATGT AGATGCAGCT GATGAGAAAT TCCGACGTAA GGTTGTTCAG 
TCTTATGTTG AAGGATTGTG CTGGGTTCTT CGATATTATT ACCAGGGCTG TGCTTCCTGG 
AAGTGGTATT ACCCATTCCA TTATGCGCCG TTTGCCTCAG ACTTTGAAGG TATTGCAGAC 
ATGCCTTCTG AATTTGAAAA GGGCACAAAA CCGTTTAAAC CACTGGAACA GCTAATGGGG 
GTTTTTCCAG CTGCAAGTGG TAACTTTTTA CCTCCAACAT GGCGGAAGCT CATGAGTGAC 
CCTGATTCTA GTATAATTGA CTTCTATCCT GAAGACTTTG CTATTGATTT GAATGGGAAG 
AAGTATGCAT GGCAAGGTGT TGCTCTGTTG CCATTTGTGG ATGAGCGAAG GCTGCGAGCG 
GCCCTAGAAG AGGTGTACCC AGACCTCACT CCAGAAGAGA ACAGGAGAAA TAGTCTTGGA 
AGTGATGTTT TGTTTGTGGG AAAAGTTCAT CCACTACACG ACTTCATTTT AGAGCTGTAT 
CAGACAGGTT CTACAGAGCC AGTAGATGTG CCGCCTGAGT TGTGTCACGG GATTCAAGGG 
AAGTTTTCTT TGGATGAAGA AGCCATACTT CCAGACCAAA CAGTATGTTC CCCTGTGCCC 
ATGTTACGGG ACTTGACACA GAACACTGCA ATCAGTATTA ATTTTAAAGA TCCACAGTTT 
GCGGAAGATT ATGTTTTTAA AGCTATAATG CTTCCAGGAG CAAGAAAGCC AGCAGCAGTT 
CTGAAACCCG GAGACTGGGA AAAATCCAGC AATGGGCGGC AATGGAAACC CCAGCTTGGC 
TTTAACCGGG ACCGGCGGCC TGTTCACCTG GACCAGGCAG CCTTTAGAAC TTTAGGCCAT 
GTTATACCAA GAGGCTCAGG GACTGGTGTT TACAGCAACA CTGCACCCCC ACCTGCCAAT 
TACCAGGGGA ACGTATACAG GCCACTGCTG AGAGGTCAAG CTCAGATCCC AAAACTAATG 
TCAAATATGA GGCCCCAAGA TAACTGGCGA GGTCCTCCTC CTCTTTTCCA GCAGCAGAGA 
TTTGACAGAA GTGTTGGAGC TGAACCCCTA CTGCCGTGGA ACCGAATGCT CCAAACCCAA 
AATGCAGCCT TTCAGCCAAA TCAGTACCAG ATGCTGGCTG GGCCCGGAGG ATATCCACCC 
AGACGTGATG ACCATCGAGG AGGGCGACAG GGATATCCCA GAGAAGGAAG GAAGTACCCT 
TTGCCACCGC CCTCGGGAAG ATACAGTTGG AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Xrn2 ( XM_017602625.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017458114.1 Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.

Price & Availability↑

CloneID	ORa26464
Clone ID Related Accession (Same CDS sequence)	XM_006235156.3 , NM_001108596.2 , XM_017602625.1
Accession Version	XM_017602625.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2856bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	5'-3' exoribonuclease 2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (AC_000071.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGAGTCC CGGCGTTCTT CCGCTGGCTC AGCCGCAAGT ACCCGTCCAT CATTGTCAAT 
TGCGTGGAGG AGAAGCCAAA AGAATGCAAT GGTGTGAAGA TTCCAGTTGA TGCCAGTAAA 
CCTAATCCAA ATGATGTGGA GTTTGATAAT CTGTATTTGG ATATGAATGG AATCATCCAT 
CCCTGTACTC ATCCTGAAGA CAAACCAGCA CCAAAAAATG AAGATGAAAT GATGGTTGCA 
ATTTTTGAGT ACATTGACAG ACTTTTCAAT ATTGTAAGAC CAAGAAGACT TCTCTATATG 
GCAATAGATG GAGTGGCACC ACGTGCCAAA ATGAACCAGC AGCGTTCAAG GAGGTTCAGA 
GCATCTAAGG AAGGAATGGA AGCCGCAGTT GAGAAGCAGC GAGTCAGAGA GGAAATACTT 
GCAAAAGGTG GCTTTCTTCC TCCAGAAGAA ATAAAAGAAA GATTTGACAG CAACTGTATT 
ACACCAGGAA CTGAGTTCAT GGACAATCTT GCTAAATGCC TTCGCTATTA CATAGCTGAT 
CGTTTAAATA ATGACCCCGG GTGGAAAAAT TTGACAGTTA TATTATCTGA CGCTAGTGCG 
CCTGGTGAAG GAGAACACAA AATCATGGAT TACATTAGAA GACAAAGAGC CCAGCCTAAC 
CATGACCCAA ATACTCATCA TTGTTTATGT GGAGCTGATG CTGATCTCAT TATGCTTGGT 
CTTGCTACAC ATGAACCTAA CTTCACCATA ATCAGAGAAG AATTCAAACC AAATAAACCT 
AAACCATGTG CTCTTTGTAA TCAGTTTGGA CACGAGGTCA AGGACTGTGA AGGTTTGCCC 
AGAGAAAAGA AGGGGAAGCA TGATGAACTT GCAGATAGTC TTCCTTGTGC AGAAGGGGAG 
TTCATCTTCC TTCGGCTGAA TGTCCTTCGA GAGTATCTGG AACGAGAGCT CACCATGGCC 
AGCTTACCGT TCCCATTTGA TGTGGAGAGG AGCATCGATG ACTGGGTGTT CATGTGCTTC 
TTTGTGGGGA ATGATTTCCT TCCTCACTTG CCGTCACTAG AGATTAGGGA AGGTGCAATT 
GATCGTTTGG TTAACATATA CAAAAACGTG GTACACAAAA CTGGGGGTTA CCTTACAGAA 
AGTGGTTATG TCAATCTACA AAGAGTACAG ATGATCATGT TAGCAGTTGG TGAAGTTGAG 
GATAGCATTT TTAAAAAGAG AAAAGATGAT GAGGACAGTT TTAGAAGACG ACAGAAAGAA 
AAAAGAAAGA GGATGAAGAG AGATCAACCA GCTTTTACTC CTAGTGGAAT ATTAACACCT 
TACGCTTTGG GTTCAAGAAA TTCTCCAGGT TGTCAAGTAG CCAGTAATCC AAGACAAGCC 
GCCTATGAAA TGAGGATGCA GAGTAACTCT AGTCCTTCAA TATCCCCTAA TACAAGTTTT 
GCATCTGATG GCTCCCCATC TCCACTAGGA GGACTTAAGA GAAAAGCAGA AGATAGTGAT 
AGTGAGCCAG AGCCAGAGGA TAACGTCAGG TTATGGGAAG CTGGTTGGAA GCAGCGATAC 
TACAAGAACA AATTTGATGT AGATGCAGCT GATGAGAAAT TCCGACGTAA GGTTGTTCAG 
TCTTATGTTG AAGGATTGTG CTGGGTTCTT CGATATTATT ACCAGGGCTG TGCTTCCTGG 
AAGTGGTATT ACCCATTCCA TTATGCGCCG TTTGCCTCAG ACTTTGAAGG TATTGCAGAC 
ATGCCTTCTG AATTTGAAAA GGGCACAAAA CCGTTTAAAC CACTGGAACA GCTAATGGGG 
GTTTTTCCAG CTGCAAGTGG TAACTTTTTA CCTCCAACAT GGCGGAAGCT CATGAGTGAC 
CCTGATTCTA GTATAATTGA CTTCTATCCT GAAGACTTTG CTATTGATTT GAATGGGAAG 
AAGTATGCAT GGCAAGGTGT TGCTCTGTTG CCATTTGTGG ATGAGCGAAG GCTGCGAGCG 
GCCCTAGAAG AGGTGTACCC AGACCTCACT CCAGAAGAGA ACAGGAGAAA TAGTCTTGGA 
AGTGATGTTT TGTTTGTGGG AAAAGTTCAT CCACTACACG ACTTCATTTT AGAGCTGTAT 
CAGACAGGTT CTACAGAGCC AGTAGATGTG CCGCCTGAGT TGTGTCACGG GATTCAAGGG 
AAGTTTTCTT TGGATGAAGA AGCCATACTT CCAGACCAAA CAGTATGTTC CCCTGTGCCC 
ATGTTACGGG ACTTGACACA GAACACTGCA ATCAGTATTA ATTTTAAAGA TCCACAGTTT 
GCGGAAGATT ATGTTTTTAA AGCTATAATG CTTCCAGGAG CAAGAAAGCC AGCAGCAGTT 
CTGAAACCCG GAGACTGGGA AAAATCCAGC AATGGGCGGC AATGGAAACC CCAGCTTGGC 
TTTAACCGGG ACCGGCGGCC TGTTCACCTG GACCAGGCAG CCTTTAGAAC TTTAGGCCAT 
GTTATACCAA GAGGCTCAGG GACTGGTGTT TACAGCAACA CTGCACCCCC ACCTGCCAAT 
TACCAGGGGA ACGTATACAG GCCACTGCTG AGAGGTCAAG CTCAGATCCC AAAACTAATG 
TCAAATATGA GGCCCCAAGA TAACTGGCGA GGTCCTCCTC CTCTTTTCCA GCAGCAGAGA 
TTTGACAGAA GTGTTGGAGC TGAACCCCTA CTGCCGTGGA ACCGAATGCT CCAAACCCAA 
AATGCAGCCT TTCAGCCAAA TCAGTACCAG ATGCTGGCTG GGCCCGGAGG ATATCCACCC 
AGACGTGATG ACCATCGAGG AGGGCGACAG GGATATCCCA GAGAAGGAAG GAAGTACCCT 
TTGCCACCGC CCTCGGGAAG ATACAGTTGG AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017458114.1
CDS	529..3384
Translation	MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHLPSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPYALGSRNSPGCQVASNPRQAAYEMRMQSNSSPSISPNTSFASDGSPSPLGGLKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGSDVLFVGKVHPLHDFILELYQTGSTEPVDVPPELCHGIQGKFSLDEEAILPDQTVCSPVPMLRDLTQNTAISINFKDPQFAEDYVFKAIMLPGARKPAAVLKPGDWEKSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVIPRGSGTGVYSNTAPPPANYQGNVYRPLLRGQAQIPKLMSNMRPQDNWRGPPPLFQQQRFDRSVGAEPLLPWNRMLQTQNAAFQPNQYQMLAGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN

Target ORF information:

RefSeq Version	XM_017602625.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017602625.1

ORF Insert Sequence:

ATGGGAGTCC CGGCGTTCTT CCGCTGGCTC AGCCGCAAGT ACCCGTCCAT CATTGTCAAT 
TGCGTGGAGG AGAAGCCAAA AGAATGCAAT GGTGTGAAGA TTCCAGTTGA TGCCAGTAAA 
CCTAATCCAA ATGATGTGGA GTTTGATAAT CTGTATTTGG ATATGAATGG AATCATCCAT 
CCCTGTACTC ATCCTGAAGA CAAACCAGCA CCAAAAAATG AAGATGAAAT GATGGTTGCA 
ATTTTTGAGT ACATTGACAG ACTTTTCAAT ATTGTAAGAC CAAGAAGACT TCTCTATATG 
GCAATAGATG GAGTGGCACC ACGTGCCAAA ATGAACCAGC AGCGTTCAAG GAGGTTCAGA 
GCATCTAAGG AAGGAATGGA AGCCGCAGTT GAGAAGCAGC GAGTCAGAGA GGAAATACTT 
GCAAAAGGTG GCTTTCTTCC TCCAGAAGAA ATAAAAGAAA GATTTGACAG CAACTGTATT 
ACACCAGGAA CTGAGTTCAT GGACAATCTT GCTAAATGCC TTCGCTATTA CATAGCTGAT 
CGTTTAAATA ATGACCCCGG GTGGAAAAAT TTGACAGTTA TATTATCTGA CGCTAGTGCG 
CCTGGTGAAG GAGAACACAA AATCATGGAT TACATTAGAA GACAAAGAGC CCAGCCTAAC 
CATGACCCAA ATACTCATCA TTGTTTATGT GGAGCTGATG CTGATCTCAT TATGCTTGGT 
CTTGCTACAC ATGAACCTAA CTTCACCATA ATCAGAGAAG AATTCAAACC AAATAAACCT 
AAACCATGTG CTCTTTGTAA TCAGTTTGGA CACGAGGTCA AGGACTGTGA AGGTTTGCCC 
AGAGAAAAGA AGGGGAAGCA TGATGAACTT GCAGATAGTC TTCCTTGTGC AGAAGGGGAG 
TTCATCTTCC TTCGGCTGAA TGTCCTTCGA GAGTATCTGG AACGAGAGCT CACCATGGCC 
AGCTTACCGT TCCCATTTGA TGTGGAGAGG AGCATCGATG ACTGGGTGTT CATGTGCTTC 
TTTGTGGGGA ATGATTTCCT TCCTCACTTG CCGTCACTAG AGATTAGGGA AGGTGCAATT 
GATCGTTTGG TTAACATATA CAAAAACGTG GTACACAAAA CTGGGGGTTA CCTTACAGAA 
AGTGGTTATG TCAATCTACA AAGAGTACAG ATGATCATGT TAGCAGTTGG TGAAGTTGAG 
GATAGCATTT TTAAAAAGAG AAAAGATGAT GAGGACAGTT TTAGAAGACG ACAGAAAGAA 
AAAAGAAAGA GGATGAAGAG AGATCAACCA GCTTTTACTC CTAGTGGAAT ATTAACACCT 
TACGCTTTGG GTTCAAGAAA TTCTCCAGGT TGTCAAGTAG CCAGTAATCC AAGACAAGCC 
GCCTATGAAA TGAGGATGCA GAGTAACTCT AGTCCTTCAA TATCCCCTAA TACAAGTTTT 
GCATCTGATG GCTCCCCATC TCCACTAGGA GGACTTAAGA GAAAAGCAGA AGATAGTGAT 
AGTGAGCCAG AGCCAGAGGA TAACGTCAGG TTATGGGAAG CTGGTTGGAA GCAGCGATAC 
TACAAGAACA AATTTGATGT AGATGCAGCT GATGAGAAAT TCCGACGTAA GGTTGTTCAG 
TCTTATGTTG AAGGATTGTG CTGGGTTCTT CGATATTATT ACCAGGGCTG TGCTTCCTGG 
AAGTGGTATT ACCCATTCCA TTATGCGCCG TTTGCCTCAG ACTTTGAAGG TATTGCAGAC 
ATGCCTTCTG AATTTGAAAA GGGCACAAAA CCGTTTAAAC CACTGGAACA GCTAATGGGG 
GTTTTTCCAG CTGCAAGTGG TAACTTTTTA CCTCCAACAT GGCGGAAGCT CATGAGTGAC 
CCTGATTCTA GTATAATTGA CTTCTATCCT GAAGACTTTG CTATTGATTT GAATGGGAAG 
AAGTATGCAT GGCAAGGTGT TGCTCTGTTG CCATTTGTGG ATGAGCGAAG GCTGCGAGCG 
GCCCTAGAAG AGGTGTACCC AGACCTCACT CCAGAAGAGA ACAGGAGAAA TAGTCTTGGA 
AGTGATGTTT TGTTTGTGGG AAAAGTTCAT CCACTACACG ACTTCATTTT AGAGCTGTAT 
CAGACAGGTT CTACAGAGCC AGTAGATGTG CCGCCTGAGT TGTGTCACGG GATTCAAGGG 
AAGTTTTCTT TGGATGAAGA AGCCATACTT CCAGACCAAA CAGTATGTTC CCCTGTGCCC 
ATGTTACGGG ACTTGACACA GAACACTGCA ATCAGTATTA ATTTTAAAGA TCCACAGTTT 
GCGGAAGATT ATGTTTTTAA AGCTATAATG CTTCCAGGAG CAAGAAAGCC AGCAGCAGTT 
CTGAAACCCG GAGACTGGGA AAAATCCAGC AATGGGCGGC AATGGAAACC CCAGCTTGGC 
TTTAACCGGG ACCGGCGGCC TGTTCACCTG GACCAGGCAG CCTTTAGAAC TTTAGGCCAT 
GTTATACCAA GAGGCTCAGG GACTGGTGTT TACAGCAACA CTGCACCCCC ACCTGCCAAT 
TACCAGGGGA ACGTATACAG GCCACTGCTG AGAGGTCAAG CTCAGATCCC AAAACTAATG 
TCAAATATGA GGCCCCAAGA TAACTGGCGA GGTCCTCCTC CTCTTTTCCA GCAGCAGAGA 
TTTGACAGAA GTGTTGGAGC TGAACCCCTA CTGCCGTGGA ACCGAATGCT CCAAACCCAA 
AATGCAGCCT TTCAGCCAAA TCAGTACCAG ATGCTGGCTG GGCCCGGAGG ATATCCACCC 
AGACGTGATG ACCATCGAGG AGGGCGACAG GGATATCCCA GAGAAGGAAG GAAGTACCCT 
TTGCCACCGC CCTCGGGAAG ATACAGTTGG AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Xrn2 ( NM_001108596.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102066.2 Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.

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CloneID	ORa26464
Clone ID Related Accession (Same CDS sequence)	XM_006235156.3 , NM_001108596.2 , XM_017602625.1
Accession Version	NM_001108596.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2856bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-02
Organism	Rattus norvegicus(Norway rat)
Product	5'-3' exoribonuclease 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07054104.1, AABR07054105.1, AABR07054106.1 and FQ201757.1. On or before Sep 3, 2019 this sequence version replaced XM_006235156.3, XM_017602625.1, NM_001108596.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. This RefSeq transcript is based on transcript alignments from orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END##

ATGGGAGTCC CGGCGTTCTT CCGCTGGCTC AGCCGCAAGT ACCCGTCCAT CATTGTCAAT 
TGCGTGGAGG AGAAGCCAAA AGAATGCAAT GGTGTGAAGA TTCCAGTTGA TGCCAGTAAA 
CCTAATCCAA ATGATGTGGA GTTTGATAAT CTGTATTTGG ATATGAATGG AATCATCCAT 
CCCTGTACTC ATCCTGAAGA CAAACCAGCA CCAAAAAATG AAGATGAAAT GATGGTTGCA 
ATTTTTGAGT ACATTGACAG ACTTTTCAAT ATTGTAAGAC CAAGAAGACT TCTCTATATG 
GCAATAGATG GAGTGGCACC ACGTGCCAAA ATGAACCAGC AGCGTTCAAG GAGGTTCAGA 
GCATCTAAGG AAGGAATGGA AGCCGCAGTT GAGAAGCAGC GAGTCAGAGA GGAAATACTT 
GCAAAAGGTG GCTTTCTTCC TCCAGAAGAA ATAAAAGAAA GATTTGACAG CAACTGTATT 
ACACCAGGAA CTGAGTTCAT GGACAATCTT GCTAAATGCC TTCGCTATTA CATAGCTGAT 
CGTTTAAATA ATGACCCCGG GTGGAAAAAT TTGACAGTTA TATTATCTGA CGCTAGTGCG 
CCTGGTGAAG GAGAACACAA AATCATGGAT TACATTAGAA GACAAAGAGC CCAGCCTAAC 
CATGACCCAA ATACTCATCA TTGTTTATGT GGAGCTGATG CTGATCTCAT TATGCTTGGT 
CTTGCTACAC ATGAACCTAA CTTCACCATA ATCAGAGAAG AATTCAAACC AAATAAACCT 
AAACCATGTG CTCTTTGTAA TCAGTTTGGA CACGAGGTCA AGGACTGTGA AGGTTTGCCC 
AGAGAAAAGA AGGGGAAGCA TGATGAACTT GCAGATAGTC TTCCTTGTGC AGAAGGGGAG 
TTCATCTTCC TTCGGCTGAA TGTCCTTCGA GAGTATCTGG AACGAGAGCT CACCATGGCC 
AGCTTACCGT TCCCATTTGA TGTGGAGAGG AGCATCGATG ACTGGGTGTT CATGTGCTTC 
TTTGTGGGGA ATGATTTCCT TCCTCACTTG CCGTCACTAG AGATTAGGGA AGGTGCAATT 
GATCGTTTGG TTAACATATA CAAAAACGTG GTACACAAAA CTGGGGGTTA CCTTACAGAA 
AGTGGTTATG TCAATCTACA AAGAGTACAG ATGATCATGT TAGCAGTTGG TGAAGTTGAG 
GATAGCATTT TTAAAAAGAG AAAAGATGAT GAGGACAGTT TTAGAAGACG ACAGAAAGAA 
AAAAGAAAGA GGATGAAGAG AGATCAACCA GCTTTTACTC CTAGTGGAAT ATTAACACCT 
TACGCTTTGG GTTCAAGAAA TTCTCCAGGT TGTCAAGTAG CCAGTAATCC AAGACAAGCC 
GCCTATGAAA TGAGGATGCA GAGTAACTCT AGTCCTTCAA TATCCCCTAA TACAAGTTTT 
GCATCTGATG GCTCCCCATC TCCACTAGGA GGACTTAAGA GAAAAGCAGA AGATAGTGAT 
AGTGAGCCAG AGCCAGAGGA TAACGTCAGG TTATGGGAAG CTGGTTGGAA GCAGCGATAC 
TACAAGAACA AATTTGATGT AGATGCAGCT GATGAGAAAT TCCGACGTAA GGTTGTTCAG 
TCTTATGTTG AAGGATTGTG CTGGGTTCTT CGATATTATT ACCAGGGCTG TGCTTCCTGG 
AAGTGGTATT ACCCATTCCA TTATGCGCCG TTTGCCTCAG ACTTTGAAGG TATTGCAGAC 
ATGCCTTCTG AATTTGAAAA GGGCACAAAA CCGTTTAAAC CACTGGAACA GCTAATGGGG 
GTTTTTCCAG CTGCAAGTGG TAACTTTTTA CCTCCAACAT GGCGGAAGCT CATGAGTGAC 
CCTGATTCTA GTATAATTGA CTTCTATCCT GAAGACTTTG CTATTGATTT GAATGGGAAG 
AAGTATGCAT GGCAAGGTGT TGCTCTGTTG CCATTTGTGG ATGAGCGAAG GCTGCGAGCG 
GCCCTAGAAG AGGTGTACCC AGACCTCACT CCAGAAGAGA ACAGGAGAAA TAGTCTTGGA 
AGTGATGTTT TGTTTGTGGG AAAAGTTCAT CCACTACACG ACTTCATTTT AGAGCTGTAT 
CAGACAGGTT CTACAGAGCC AGTAGATGTG CCGCCTGAGT TGTGTCACGG GATTCAAGGG 
AAGTTTTCTT TGGATGAAGA AGCCATACTT CCAGACCAAA CAGTATGTTC CCCTGTGCCC 
ATGTTACGGG ACTTGACACA GAACACTGCA ATCAGTATTA ATTTTAAAGA TCCACAGTTT 
GCGGAAGATT ATGTTTTTAA AGCTATAATG CTTCCAGGAG CAAGAAAGCC AGCAGCAGTT 
CTGAAACCCG GAGACTGGGA AAAATCCAGC AATGGGCGGC AATGGAAACC CCAGCTTGGC 
TTTAACCGGG ACCGGCGGCC TGTTCACCTG GACCAGGCAG CCTTTAGAAC TTTAGGCCAT 
GTTATACCAA GAGGCTCAGG GACTGGTGTT TACAGCAACA CTGCACCCCC ACCTGCCAAT 
TACCAGGGGA ACGTATACAG GCCACTGCTG AGAGGTCAAG CTCAGATCCC AAAACTAATG 
TCAAATATGA GGCCCCAAGA TAACTGGCGA GGTCCTCCTC CTCTTTTCCA GCAGCAGAGA 
TTTGACAGAA GTGTTGGAGC TGAACCCCTA CTGCCGTGGA ACCGAATGCT CCAAACCCAA 
AATGCAGCCT TTCAGCCAAA TCAGTACCAG ATGCTGGCTG GGCCCGGAGG ATATCCACCC 
AGACGTGATG ACCATCGAGG AGGGCGACAG GGATATCCCA GAGAAGGAAG GAAGTACCCT 
TTGCCACCGC CCTCGGGAAG ATACAGTTGG AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102066.2
CDS	46..2901
Translation	MGVPAFFRWLSRKYPSIIVNCVEEKPKECNGVKIPVDASKPNPNDVEFDNLYLDMNGIIHPCTHPEDKPAPKNEDEMMVAIFEYIDRLFNIVRPRRLLYMAIDGVAPRAKMNQQRSRRFRASKEGMEAAVEKQRVREEILAKGGFLPPEEIKERFDSNCITPGTEFMDNLAKCLRYYIADRLNNDPGWKNLTVILSDASAPGEGEHKIMDYIRRQRAQPNHDPNTHHCLCGADADLIMLGLATHEPNFTIIREEFKPNKPKPCALCNQFGHEVKDCEGLPREKKGKHDELADSLPCAEGEFIFLRLNVLREYLERELTMASLPFPFDVERSIDDWVFMCFFVGNDFLPHLPSLEIREGAIDRLVNIYKNVVHKTGGYLTESGYVNLQRVQMIMLAVGEVEDSIFKKRKDDEDSFRRRQKEKRKRMKRDQPAFTPSGILTPYALGSRNSPGCQVASNPRQAAYEMRMQSNSSPSISPNTSFASDGSPSPLGGLKRKAEDSDSEPEPEDNVRLWEAGWKQRYYKNKFDVDAADEKFRRKVVQSYVEGLCWVLRYYYQGCASWKWYYPFHYAPFASDFEGIADMPSEFEKGTKPFKPLEQLMGVFPAASGNFLPPTWRKLMSDPDSSIIDFYPEDFAIDLNGKKYAWQGVALLPFVDERRLRAALEEVYPDLTPEENRRNSLGSDVLFVGKVHPLHDFILELYQTGSTEPVDVPPELCHGIQGKFSLDEEAILPDQTVCSPVPMLRDLTQNTAISINFKDPQFAEDYVFKAIMLPGARKPAAVLKPGDWEKSSNGRQWKPQLGFNRDRRPVHLDQAAFRTLGHVIPRGSGTGVYSNTAPPPANYQGNVYRPLLRGQAQIPKLMSNMRPQDNWRGPPPLFQQQRFDRSVGAEPLLPWNRMLQTQNAAFQPNQYQMLAGPGGYPPRRDDHRGGRQGYPREGRKYPLPPPSGRYSWN

Target ORF information:

RefSeq Version	NM_001108596.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus 5'-3' exoribonuclease 2 (Xrn2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108596.2

ORF Insert Sequence:

ATGGGAGTCC CGGCGTTCTT CCGCTGGCTC AGCCGCAAGT ACCCGTCCAT CATTGTCAAT 
TGCGTGGAGG AGAAGCCAAA AGAATGCAAT GGTGTGAAGA TTCCAGTTGA TGCCAGTAAA 
CCTAATCCAA ATGATGTGGA GTTTGATAAT CTGTATTTGG ATATGAATGG AATCATCCAT 
CCCTGTACTC ATCCTGAAGA CAAACCAGCA CCAAAAAATG AAGATGAAAT GATGGTTGCA 
ATTTTTGAGT ACATTGACAG ACTTTTCAAT ATTGTAAGAC CAAGAAGACT TCTCTATATG 
GCAATAGATG GAGTGGCACC ACGTGCCAAA ATGAACCAGC AGCGTTCAAG GAGGTTCAGA 
GCATCTAAGG AAGGAATGGA AGCCGCAGTT GAGAAGCAGC GAGTCAGAGA GGAAATACTT 
GCAAAAGGTG GCTTTCTTCC TCCAGAAGAA ATAAAAGAAA GATTTGACAG CAACTGTATT 
ACACCAGGAA CTGAGTTCAT GGACAATCTT GCTAAATGCC TTCGCTATTA CATAGCTGAT 
CGTTTAAATA ATGACCCCGG GTGGAAAAAT TTGACAGTTA TATTATCTGA CGCTAGTGCG 
CCTGGTGAAG GAGAACACAA AATCATGGAT TACATTAGAA GACAAAGAGC CCAGCCTAAC 
CATGACCCAA ATACTCATCA TTGTTTATGT GGAGCTGATG CTGATCTCAT TATGCTTGGT 
CTTGCTACAC ATGAACCTAA CTTCACCATA ATCAGAGAAG AATTCAAACC AAATAAACCT 
AAACCATGTG CTCTTTGTAA TCAGTTTGGA CACGAGGTCA AGGACTGTGA AGGTTTGCCC 
AGAGAAAAGA AGGGGAAGCA TGATGAACTT GCAGATAGTC TTCCTTGTGC AGAAGGGGAG 
TTCATCTTCC TTCGGCTGAA TGTCCTTCGA GAGTATCTGG AACGAGAGCT CACCATGGCC 
AGCTTACCGT TCCCATTTGA TGTGGAGAGG AGCATCGATG ACTGGGTGTT CATGTGCTTC 
TTTGTGGGGA ATGATTTCCT TCCTCACTTG CCGTCACTAG AGATTAGGGA AGGTGCAATT 
GATCGTTTGG TTAACATATA CAAAAACGTG GTACACAAAA CTGGGGGTTA CCTTACAGAA 
AGTGGTTATG TCAATCTACA AAGAGTACAG ATGATCATGT TAGCAGTTGG TGAAGTTGAG 
GATAGCATTT TTAAAAAGAG AAAAGATGAT GAGGACAGTT TTAGAAGACG ACAGAAAGAA 
AAAAGAAAGA GGATGAAGAG AGATCAACCA GCTTTTACTC CTAGTGGAAT ATTAACACCT 
TACGCTTTGG GTTCAAGAAA TTCTCCAGGT TGTCAAGTAG CCAGTAATCC AAGACAAGCC 
GCCTATGAAA TGAGGATGCA GAGTAACTCT AGTCCTTCAA TATCCCCTAA TACAAGTTTT 
GCATCTGATG GCTCCCCATC TCCACTAGGA GGACTTAAGA GAAAAGCAGA AGATAGTGAT 
AGTGAGCCAG AGCCAGAGGA TAACGTCAGG TTATGGGAAG CTGGTTGGAA GCAGCGATAC 
TACAAGAACA AATTTGATGT AGATGCAGCT GATGAGAAAT TCCGACGTAA GGTTGTTCAG 
TCTTATGTTG AAGGATTGTG CTGGGTTCTT CGATATTATT ACCAGGGCTG TGCTTCCTGG 
AAGTGGTATT ACCCATTCCA TTATGCGCCG TTTGCCTCAG ACTTTGAAGG TATTGCAGAC 
ATGCCTTCTG AATTTGAAAA GGGCACAAAA CCGTTTAAAC CACTGGAACA GCTAATGGGG 
GTTTTTCCAG CTGCAAGTGG TAACTTTTTA CCTCCAACAT GGCGGAAGCT CATGAGTGAC 
CCTGATTCTA GTATAATTGA CTTCTATCCT GAAGACTTTG CTATTGATTT GAATGGGAAG 
AAGTATGCAT GGCAAGGTGT TGCTCTGTTG CCATTTGTGG ATGAGCGAAG GCTGCGAGCG 
GCCCTAGAAG AGGTGTACCC AGACCTCACT CCAGAAGAGA ACAGGAGAAA TAGTCTTGGA 
AGTGATGTTT TGTTTGTGGG AAAAGTTCAT CCACTACACG ACTTCATTTT AGAGCTGTAT 
CAGACAGGTT CTACAGAGCC AGTAGATGTG CCGCCTGAGT TGTGTCACGG GATTCAAGGG 
AAGTTTTCTT TGGATGAAGA AGCCATACTT CCAGACCAAA CAGTATGTTC CCCTGTGCCC 
ATGTTACGGG ACTTGACACA GAACACTGCA ATCAGTATTA ATTTTAAAGA TCCACAGTTT 
GCGGAAGATT ATGTTTTTAA AGCTATAATG CTTCCAGGAG CAAGAAAGCC AGCAGCAGTT 
CTGAAACCCG GAGACTGGGA AAAATCCAGC AATGGGCGGC AATGGAAACC CCAGCTTGGC 
TTTAACCGGG ACCGGCGGCC TGTTCACCTG GACCAGGCAG CCTTTAGAAC TTTAGGCCAT 
GTTATACCAA GAGGCTCAGG GACTGGTGTT TACAGCAACA CTGCACCCCC ACCTGCCAAT 
TACCAGGGGA ACGTATACAG GCCACTGCTG AGAGGTCAAG CTCAGATCCC AAAACTAATG 
TCAAATATGA GGCCCCAAGA TAACTGGCGA GGTCCTCCTC CTCTTTTCCA GCAGCAGAGA 
TTTGACAGAA GTGTTGGAGC TGAACCCCTA CTGCCGTGGA ACCGAATGCT CCAAACCCAA 
AATGCAGCCT TTCAGCCAAA TCAGTACCAG ATGCTGGCTG GGCCCGGAGG ATATCCACCC 
AGACGTGATG ACCATCGAGG AGGGCGACAG GGATATCCCA GAGAAGGAAG GAAGTACCCT 
TTGCCACCGC CCTCGGGAAG ATACAGTTGG AATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Pilocarpine-induced seizures trigger differential regulation of microRNA-stability related genes in rat hippocampal neurons.
Scientific reports620969(2016 Feb)
Kinjo ER,Higa GS,Santos BA,de Sousa E,Damico MV,Walter LT,Morya E,Valle AC,Britto LR,Kihara AH

The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA.
RNA (New York, N.Y.)20(4)540-50(2014 Apr)
Sloan KE,Bohnsack MT,Schneider C,Watkins NJ

Gene expression signatures of primary and metastatic uterine leiomyosarcoma.
Human pathology45(4)691-700(2014 Apr)
Davidson B,Abeler VM,F?rsund M,Holth A,Yang Y,Kobayashi Y,Chen L,Kristensen GB,Shih IeM,Wang TL

A possible new mechanism for the control of miRNA expression in neurons.
Experimental neurology248546-58(2013 Oct)
Kinjo ER,Higa GS,de Sousa E,Casado OA,Damico MV,Britto LR,Kihara AH

Developmental and functional expression of miRNA-stability related genes in the nervous system.
PloS one8(5)e56908(2013)
de Sousa ?,Walter LT,Higa GS,Casado OA,Kihara AH

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Xrn2 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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