Gene Symbol | Tbc1d20 |
Entrez Gene ID | 362237 |
Full Name | TBC1 domain family, member 20 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Tbc1d20 cDNA ORF clone
Gene Symbol | Tbc1d20 |
Entrez Gene ID | 362237 |
Full Name | TBC1 domain family, member 20 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001004281.1 | NP_001004281.1 | TBC1 domain family member 20 |
XM_008762348.1 | XP_008760570.1 | TBC1 domain family member 20 isoform X1 |
Canis lupus familiaris (dog) | TBC1D20 | XP_861927.2 |
Mus musculus (house mouse) | Tbc1d20 | NP_077158.1 |
Rattus norvegicus (Norway rat) | Tbc1d20 | NP_001004281.1 |
Caenorhabditis elegans (roundworm) | tbc-20 | NP_497068.2 |
Xenopus tropicalis (tropical clawed frog) | tbc1d20.1 | NP_001016881.1 |
Homo sapiens (human) | TBC1D20 | NP_653229.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008312 | XP_317154.4 |
Schizosaccharomyces pombe (fission yeast) | gyp10 | NP_595501.1 |
Bos taurus (cattle) | TBC1D20 | NP_001033118.1 |
Gallus gallus (chicken) | TBC1D20 | XP_001235015.2 |
Danio rerio (zebrafish) | tbc1d20 | NP_001020343.1 |
Neurospora crassa | NCU05272 | XP_961909.1 |
Pan troglodytes (chimpanzee) | TBC1D20 | XP_003316844.1 |
TBC1D20 | XP_001107845.1 | |
Drosophila melanogaster (fruit fly) | CG17883 | NP_001036448.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06021 | XP_003711868.1 |
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.
Liegel RP, Handley MT, Ronchetti A, Brown S, Langemeyer L, Linford A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V, Sheridan E, Abdel-Salam GM, Terhal PA, Faravelli F, Accorsi P, Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA, Sidjanin DJ
American journal of human genetics93(6)1001-14(2013 Dec)
Role for TBC1D20 and Rab1 in hepatitis C virus replication via interaction with lipid droplet-bound nonstructural protein 5A.
Nevo-Yassaf I, Yaffe Y, Asher M, Ravid O, Eizenberg S, Henis YI, Nahmias Y, Hirschberg K, Sklan EH
Journal of virology86(12)6491-502(2012 Jun)
Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment.
Zenner HL, Yoshimura S, Barr FA, Crump CM
Journal of virology85(16)8012-21(2011 Aug)
A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication.
Sklan EH, Staschke K, Oakes TM, Elazar M, Winters M, Aroeti B, Danieli T, Glenn JS
Journal of virology81(20)11096-105(2007 Oct)
Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells.
Haas AK, Yoshimura S, Stephens DJ, Preisinger C, Fuchs E, Barr FA
Journal of cell science120(Pt 17)2997-3010(2007 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Tbc1d20 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tbc1d20 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa10344 | |
Clone ID Related Accession (Same CDS sequence) | NM_001004281.1 | |
Accession Version | NM_001004281.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-26 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | TBC1 domain family member 20 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079383.1. On Sep 10, 2004 this sequence version replaced XM_342544.1. ##Evidence-Data-START## Transcript exon combination :: BC079383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCCTCC GGCCCTCAGA GGGCGACGGC TCCGCCGGCC GCTGGAACCG CGGCTCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001004281.1 |
CDS | 58..1266 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001004281.1 |
1 | ATGGCCCTCC GGCCCTCAGA GGGCGACGGC TCCGCCGGCC GCTGGAACCG CGGCTCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa48165 | |
Clone ID Related Accession (Same CDS sequence) | XM_008762348.1 | |
Accession Version | XM_008762348.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | TBC1 domain family member 20 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005102.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCCTCC GGCCCTCAGA GGGCGACGGC TCCGCCGGCC GCTGGAACCG CGGCTCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_008760570.1 |
CDS | 207..1352 |
Translation |
Target ORF information:
Target ORF information:
|
XM_008762348.1 |
1 | ATGGCCCTCC GGCCCTCAGA GGGCGACGGC TCCGCCGGCC GCTGGAACCG CGGCTCAGGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. |
Role for TBC1D20 and Rab1 in hepatitis C virus replication via interaction with lipid droplet-bound nonstructural protein 5A. |
Analysis of Rab GTPase-activating proteins indicates that Rab1a/b and Rab43 are important for herpes simplex virus 1 secondary envelopment. |
A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication. |
Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells. |