Cul1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Cul1
Entrez Gene ID	362356
Full Name	cullin 1
General protein information	Preferred Names cullin 1 Names cullin-1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 4 Map Location: 4q24

mRNA and Protein(s)

mRNA	Protein	Name
XM_006236411.2	XP_006236473.1	cullin-1 isoform X2
NM_001108627.2	NP_001102097.1	cullin-1
XM_006236409.2	XP_006236471.1	cullin-1 isoform X1
XM_006236410.3	XP_006236472.1	cullin-1 isoform X1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Cul1	NP_036172.1
Danio rerio (zebrafish)	cul1b	NP_998660.1
Neurospora crassa	NCU05204	XP_962203.2
Xenopus tropicalis (tropical clawed frog)	cul1	NP_001039255.1
	CUL1	XP_002803558.1
Canis lupus familiaris (dog)	CUL1	XP_848402.1
Bos taurus (cattle)	CUL1	NP_001180162.1
Schizosaccharomyces pombe (fission yeast)	cul1	NP_594259.1
Magnaporthe oryzae (rice blast fungus)	MGG_07145	XP_003715342.1
Rattus norvegicus (Norway rat)	Cul1	NP_001102097.1
Gallus gallus (chicken)	CUL1	XP_418878.3
Drosophila melanogaster (fruit fly)	lin19	NP_724622.1
Pan troglodytes (chimpanzee)	CUL1	NP_001233533.1
Caenorhabditis elegans (roundworm)	cul-1	NP_499309.1
Homo sapiens (human)	CUL1	NP_003583.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP008007	XP_317457.4

Gene Ontology
Bibliography

Related articles in PubMed

The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.
Reiterer V, Figueras-Puig C, Le Guerroue F, Confalonieri S, Vecchi M, Jalapothu D, Kanse SM, Deshaies RJ, Di Fiore PP, Behrends C, Farhan H
The EMBO journal36(3)260-273(2017 Feb)

FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51.
Chu WK, Payne MJ, Beli P, Hanada K, Choudhary C, Hickson ID
Nature communications65931(2015 Jan)

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism.
Hayes JD, Dinkova-Kostova AT
Trends in biochemical sciences39(4)199-218(2014 Apr)

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes.
Hirano A, Yumimoto K, Tsunematsu R, Matsumoto M, Oyama M, Kozuka-Hata H, Nakagawa T, Lanjakornsiripan D, Nakayama KI, Fukada Y
Cell152(5)1106-18(2013 Feb)

SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.
Fern?ndez-S?iz V, Targosz BS, Lemeer S, Eichner R, Langer C, Bullinger L, Reiter C, Slotta-Huspenina J, Schroeder S, Knorn AM, Kurutz J, Peschel C, Pagano M, Kuster B, Bassermann F
Nature cell biology15(1)72-81(2013 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Cul1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cul1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa07952	NM_001108627.2 Latest version!	Rattus norvegicus cullin 1 (Cul1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa07952	XM_006236411.2 Latest version!	Rattus norvegicus cullin 1 (Cul1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa27231	XM_006236409.2 Latest version!	Rattus norvegicus cullin 1 (Cul1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa27231	XM_006236410.3 Latest version!	Rattus norvegicus cullin 1 (Cul1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Cul1 ( NM_001108627.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001102097.1 Rattus norvegicus cullin 1 (Cul1), mRNA.

Price & Availability↑

CloneID	ORa07952
Clone ID Related Accession (Same CDS sequence)	XM_006236411.2 , NM_001108627.2
Accession Version	NM_001108627.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2331bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	cullin-1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC161932.1. On Apr 6, 2008 this sequence version replaced NM_001108627.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC161932.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END##

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG AAATGCATTG ATATTCTCAT CGAAAAAGAA 
TATTTGGAGC GAGTCGATGG TGAGAAGGAC ACCTACAGTT ACTTGGCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001102097.1
CDS	255..2585
Translation	MSSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA

Target ORF information:

RefSeq Version	NM_001108627.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cullin 1 (Cul1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001108627.2

ORF Insert Sequence:

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG AAATGCATTG ATATTCTCAT CGAAAAAGAA 
TATTTGGAGC GAGTCGATGG TGAGAAGGAC ACCTACAGTT ACTTGGCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul1 ( XM_006236411.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236473.1 Rattus norvegicus cullin 1 (Cul1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa07952
Clone ID Related Accession (Same CDS sequence)	XM_006236411.2 , NM_001108627.2
Accession Version	XM_006236411.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2331bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cullin-1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236411.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG AAATGCATTG ATATTCTCAT CGAAAAAGAA 
TATTTGGAGC GAGTCGATGG TGAGAAGGAC ACCTACAGTT ACTTGGCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236473.1
CDS	245..2575
Translation	MSSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKKCIDILIEKEYLERVDGEKDTYSYLA

Target ORF information:

RefSeq Version	XM_006236411.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cullin 1 (Cul1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236411.2

ORF Insert Sequence:

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG AAATGCATTG ATATTCTCAT CGAAAAAGAA 
TATTTGGAGC GAGTCGATGG TGAGAAGGAC ACCTACAGTT ACTTGGCTTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul1 ( XM_006236409.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236471.1 Rattus norvegicus cullin 1 (Cul1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa27231
Clone ID Related Accession (Same CDS sequence)	XM_006236409.2 , XM_006236410.3
Accession Version	XM_006236409.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cullin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236409.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG GTCCCTCCTA GTGAAGCTTT TCCAAGGAGG 
CTGCCATATT CACCCCAGGA TGTCCCCGGA AGGAGGGCCC AGGCCAGGGG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236471.1
CDS	245..2578
Translation	MSSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKVPPSEAFPRRLPYSPQDVPGRRAQARG

Target ORF information:

RefSeq Version	XM_006236409.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cullin 1 (Cul1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236409.2

ORF Insert Sequence:

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG GTCCCTCCTA GTGAAGCTTT TCCAAGGAGG 
CTGCCATATT CACCCCAGGA TGTCCCCGGA AGGAGGGCCC AGGCCAGGGG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Cul1 ( XM_006236410.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_006236472.1 Rattus norvegicus cullin 1 (Cul1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa27231
Clone ID Related Accession (Same CDS sequence)	XM_006236409.2 , XM_006236410.3
Accession Version	XM_006236410.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	cullin-1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005103.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006236410.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG GTCCCTCCTA GTGAAGCTTT TCCAAGGAGG 
CTGCCATATT CACCCCAGGA TGTCCCCGGA AGGAGGGCCC AGGCCAGGGG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006236472.1
CDS	247..2580
Translation	MSSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQARGAGVPPSKSKKGQTPGGAQFVGLELYKRLKEFLKNYLTNLLKDGEDLMDESVLKFYTQQWEDYRFSSKVLNGICAYLNRHWVRRECDEGRKGIYEIYSLALVTWRDCLFRPLNKQVTNAVLKLIEKERNGETINTRLISGVVQSYVELGLNEDDAFAKGPTLTVYKESFESQFLADTERFYTRESTEFLQQNPVTEYMKKAEARLLEEQRRVQVYLHESTQDELARKCEQVLIEKHLEIFHTEFQNLLDADKNEDLGRMYNLVSRIQDGLGELKKLLETHIHNQGLAAIEKCGEAALNDPKMYVQTVLDVHKKYNALVMSAFNNDAGFVAALDKACGRFINNNAVTKMAQSSSKSPELLARYCDSLLKKSSKNPEEAELEDTLNQVMVVFKYIEDKDVFQKFYAKMLAKRLVHQNSASDDAEASMISKLKQACGFEYTSKLQRMFQDIGVSKDLNEQFKKHLTNSEPLDLDFSIQVLSSGSWPFQQSCTFALPSELERSYQRFTAFYASRHSGRKLTWLYQLSKGELVTNCFKNRYTLQASTFQMAILLQYNTEDAYTVQQLTDSTQIKMDILAQVLQILLKSKLLVLEDENANVDEVELKPDTLIKLYLGYKNKKLRVNINVPMKTEQKQEQETTHKNIEEDRKLLIQAAIVRIMKMRKVLKHQQLLGEVLTQLSSRFKPRVPVIKVPPSEAFPRRLPYSPQDVPGRRAQARG

Target ORF information:

RefSeq Version	XM_006236410.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus cullin 1 (Cul1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006236410.3

ORF Insert Sequence:

ATGTCATCAA ACAGGAGTCA GAATCCTCAT GGACTGAAGC AGATCGGTCT TGACCAGATC 
TGGGATGACC TCAGAGCTGG AATTCAGCAA GTGTACACCA GACAAAGCAT GGCAAAGTCC 
AGATACATGG AGCTCTACAC TCATGTTTAT AACTACTGTA CTAGTGTGCA TCAGTCCAAC 
CAAGCCCGGG GTGCTGGAGT CCCTCCTTCC AAGTCAAAAA AGGGGCAGAC TCCTGGGGGA 
GCTCAGTTTG TCGGCTTGGA GTTATACAAG CGATTGAAGG AGTTTTTGAA GAATTACTTG 
ACAAATCTTC TTAAGGATGG AGAAGATTTA ATGGATGAGA GTGTGCTGAA GTTCTACACT 
CAGCAGTGGG AAGATTACCG ATTCTCCAGC AAAGTGCTGA ATGGAATCTG TGCCTACCTC 
AATAGACATT GGGTTCGTCG CGAATGTGAT GAAGGACGAA AAGGAATATA TGAAATCTAT 
TCGCTTGCGT TGGTGACATG GAGAGATTGT TTGTTCAGGC CATTGAATAA ACAGGTAACA 
AATGCTGTTT TAAAACTGAT TGAGAAGGAA AGAAATGGCG AAACCATCAA TACAAGACTG 
ATTAGTGGAG TTGTACAATC TTATGTGGAA TTGGGACTGA ATGAAGATGA TGCATTTGCA 
AAGGGCCCTA CGTTAACAGT GTATAAAGAA TCCTTTGAAT CTCAATTTTT GGCTGACACA 
GAGAGATTTT ATACCAGAGA AAGTACTGAA TTCTTACAGC AGAACCCAGT TACTGAATAT 
ATGAAAAAGG CTGAAGCTCG TCTGCTTGAG GAACAGCGGA GAGTTCAGGT TTATCTCCAT 
GAGAGCACAC AAGATGAGCT AGCACGGAAA TGTGAGCAGG TCCTCATTGA AAAACACTTG 
GAAATTTTTC ACACAGAGTT TCAGAATTTG TTGGATGCTG ACAAGAATGA AGATTTGGGC 
CGCATGTATA ATCTTGTATC TAGAATTCAG GATGGCCTAG GAGAATTGAA AAAACTACTA 
GAGACACATA TTCATAATCA GGGTCTTGCG GCAATTGAGA AGTGTGGAGA AGCTGCTCTG 
AATGACCCCA AGATGTATGT GCAGACAGTG CTGGATGTTC ATAAAAAATA CAATGCCCTG 
GTGATGTCAG CATTCAACAA CGATGCTGGC TTCGTGGCTG CACTTGATAA GGCTTGTGGT 
CGCTTCATAA ACAACAATGC AGTTACCAAA ATGGCCCAGT CATCCAGTAA ATCCCCTGAG 
CTTCTTGCTC GGTACTGTGA CTCCTTGTTG AAGAAAAGTT CTAAGAACCC AGAAGAGGCA 
GAACTAGAAG ATACCCTCAA TCAAGTGATG GTGGTCTTCA AGTACATCGA GGACAAAGAT 
GTATTTCAGA AGTTCTATGC AAAGATGCTT GCCAAGAGAC TGGTACATCA GAACAGTGCG 
AGTGACGATG CTGAAGCAAG CATGATCTCT AAATTAAAGC AAGCTTGTGG TTTTGAGTAC 
ACTTCCAAAC TCCAGCGAAT GTTTCAAGAC ATTGGTGTAA GCAAAGATCT AAATGAACAG 
TTCAAAAAGC ACCTGACGAA TTCAGAACCA CTGGACTTGG ACTTCAGTAT TCAGGTCCTG 
AGTTCCGGAT CATGGCCCTT TCAGCAGTCT TGCACGTTTG CCTTGCCGTC AGAGTTGGAG 
CGCAGTTACC AACGGTTTAC AGCTTTCTAC GCCAGCCGTC ACAGTGGCAG AAAATTGACA 
TGGTTGTATC AACTGTCCAA AGGGGAACTA GTCACTAACT GCTTCAAAAA CAGATACACT 
TTGCAGGCGT CCACATTCCA GATGGCCATC CTGCTTCAGT ACAACACAGA AGACGCCTAT 
ACTGTGCAGC AGCTGACCGA CAGCACTCAG ATTAAAATGG ACATTTTGGC ACAAGTCCTA 
CAGATTTTAC TGAAGTCAAA ATTGCTGGTC TTAGAAGATG AAAATGCCAA TGTTGATGAG 
GTGGAATTGA AGCCAGACAC CTTAATAAAG TTATATCTTG GTTATAAAAA TAAGAAATTG 
AGGGTTAATA TCAATGTACC AATGAAAACT GAACAGAAGC AGGAACAAGA AACCACACAC 
AAAAATATAG AGGAAGACCG CAAACTACTG ATTCAGGCGG CCATCGTAAG AATCATGAAA 
ATGAGGAAGG TTCTGAAACA CCAGCAGTTA CTTGGTGAAG TCCTCACTCA GCTGTCCTCC 
AGGTTCAAAC CTCGGGTCCC AGTGATCAAG GTCCCTCCTA GTGAAGCTTT TCCAAGGAGG 
CTGCCATATT CACCCCAGGA TGTCCCCGGA AGGAGGGCCC AGGCCAGGGG TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function.
The EMBO journal36(3)260-273(2017 Feb)
Reiterer V,Figueras-Puig C,Le Guerroue F,Confalonieri S,Vecchi M,Jalapothu D,Kanse SM,Deshaies RJ,Di Fiore PP,Behrends C,Farhan H

FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51.
Nature communications65931(2015 Jan)
Chu WK,Payne MJ,Beli P,Hanada K,Choudhary C,Hickson ID

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism.
Trends in biochemical sciences39(4)199-218(2014 Apr)
Hayes JD,Dinkova-Kostova AT

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes.
Cell152(5)1106-18(2013 Feb)
Hirano A,Yumimoto K,Tsunematsu R,Matsumoto M,Oyama M,Kozuka-Hata H,Nakagawa T,Lanjakornsiripan D,Nakayama KI,Fukada Y

SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.
Nature cell biology15(1)72-81(2013 Jan)
Fern?ndez-S?iz V,Targosz BS,Lemeer S,Eichner R,Langer C,Bullinger L,Reiter C,Slotta-Huspenina J,Schroeder S,Knorn AM,Kurutz J,Peschel C,Pagano M,Kuster B,Bassermann F

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Cul1 cDNA ORF clone, Rattus norvegicus(Norway rat)

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