Gene Symbol | Ripk2 |
Entrez Gene ID | 362491 |
Full Name | receptor-interacting serine-threonine kinase 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Ripk2 cDNA ORF clone
Gene Symbol | Ripk2 |
Entrez Gene ID | 362491 |
Full Name | receptor-interacting serine-threonine kinase 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001191865.1 | NP_001178794.1 | receptor-interacting serine/threonine-protein kinase 2 |
XM_017593470.1 | XP_017448959.1 | receptor-interacting serine/threonine-protein kinase 2 isoform X1 |
Bos taurus (cattle) | RIPK2 | NP_001029782.1 |
Danio rerio (zebrafish) | ripk2 | NP_919392.2 |
Canis lupus familiaris (dog) | RIPK2 | XP_005638158.1 |
Mus musculus (house mouse) | Ripk2 | NP_620402.1 |
Pan troglodytes (chimpanzee) | RIPK2 | XP_519850.2 |
RIPK2 | XP_001084687.1 | |
Rattus norvegicus (Norway rat) | Ripk2 | NP_001178794.1 |
Xenopus tropicalis (tropical clawed frog) | ripk2 | XP_002939201.2 |
Homo sapiens (human) | RIPK2 | NP_003812.1 |
Gallus gallus (chicken) | RIPK2 | NP_001026114.1 |
High Glucose and Lipopolysaccharide Activate NOD1- RICK-NF-?B Inflammatory Signaling in Mesangial Cells.
Huang W, Gou F, Long Y, Li Y, Feng H, Zhang Q, Gao C, Chen G, Xu Y
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association124(8)512-517(2016 Sep)
Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.
Ma G, Shi B, Liu J, Zhang H, YinTao Z, Lou X, Liang D, Hou Y, Wan S, Yang W
Digestive diseases and sciences60(11)3264-70(2015 Nov)
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease.
Mohanan V, Grimes CL
The Journal of biological chemistry289(27)18987-98(2014 Jul)
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling.
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M
Molecular cell50(6)818-830(2013 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
combined results support the hypothesis that high glucose and LPS can activate the NOD1-RICK-NF-kappaB inflammatory signaling pathway via the NOD1 receptor, and may participate in the development of diabetic nephropathy.
Title: High Glucose and Lipopolysaccharide Activate NOD1- RICK-NF-?B Inflammatory Signaling in Mesangial Cells.
Nod2-Rip2-NFkappaB signaling involved in the small intestinal inflammatory injury caused by muramyl dipeptide which is transported through PepT1.
Title: Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats.
The following Ripk2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ripk2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa07869 | |
Clone ID Related Accession (Same CDS sequence) | NM_001191865.1 | |
Accession Version | NM_001191865.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | receptor-interacting serine/threonine-protein kinase 2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AABR07047366.1. On Jul 17, 2010 this sequence version replaced XM_342810.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAACGGGG ACGCCATCTG CAGCGCGCTG CCCCACATCC CCTACCACAA GCTCGCCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001178794.1 |
CDS | 135..1754 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001191865.1 |
1 | ATGAACGGGG ACGCCATCTG CAGCGCGCTG CCCCACATCC CCTACCACAA GCTCGCCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa61289 | |
Clone ID Related Accession (Same CDS sequence) | XM_017593470.1 | |
Accession Version | XM_017593470.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1329bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | receptor-interacting serine/threonine-protein kinase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCAAACG GATCATTAAA TGAGCTTCTA CACAGAAAAA CTGAATATCC TGAGATTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017448959.1 |
CDS | 312..1640 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017593470.1 |
1 | ATGCCAAACG GATCATTAAA TGAGCTTCTA CACAGAAAAA CTGAATATCC TGAGATTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
High Glucose and Lipopolysaccharide Activate NOD1- RICK-NF-?B Inflammatory Signaling in Mesangial Cells. |
Nod2-Rip2 Signaling Contributes to Intestinal Injury Induced by Muramyl Dipeptide Via Oligopeptide Transporter in Rats. |
The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease. |
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. |