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Chmp2a cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Chmp2a
Entrez Gene ID 365191
Full Name charged multivesicular body protein 2A
Synonyms RGD1305050
General protein information
Preferred Names

charged multivesicular body protein 2A

Names

charged multivesicular body protein 2a
chromatin modifying protein 2A
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

1

1q12

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006228118.2 XP_006228180.1 charged multivesicular body protein 2a isoform X2
NM_001108906.1 NP_001102376.1 charged multivesicular body protein 2a
XM_006228117.2 XP_006228179.1 charged multivesicular body protein 2a isoform X1

Pathways from BioSystems


Homologies


Xenopus tropicalis (tropical clawed frog) chmp2a NP_001005008.1
Homo sapiens (human) CHMP2A NP_940818.1
Canis lupus familiaris (dog) CHMP2A XP_850536.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP001285 XP_321862.3
Caenorhabditis elegans (roundworm) vps-2 NP_496717.1
Schizosaccharomyces pombe (fission yeast) did4 NP_593871.3
Oryza sativa (rice) Os07g0236800 NP_001059248.1
Bos taurus (cattle) CHMP2A NP_001029722.1
Mus musculus (house mouse) Chmp2a NP_081161.1
Rattus norvegicus (Norway rat) Chmp2a NP_001102376.1
Danio rerio (zebrafish) bc2 NP_998682.1
Neurospora crassa NCU00435 XP_956699.1
Pan troglodytes (chimpanzee) CHMP2A XP_003316813.1
CHMP2A XP_001099219.1
Gallus gallus (chicken) CHMP2A NP_001074361.1
Drosophila melanogaster (fruit fly) vps2 NP_651455.1
Magnaporthe oryzae (rice blast fungus) MGG_05208 XP_003712753.1
Saccharomyces cerevisiae (baker's yeast) DID4 NP_012924.2
Kluyveromyces lactis KLLA0B13343g XP_452125.1
Eremothecium gossypii AGOS_ABR002C NP_982948.1
Arabidopsis thaliana (thale cress) VPS2.1 NP_565336.1

Gene Ontology


Bibliography

Related articles in PubMed

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells.
Gu M, LaJoie D, Chen OS, von Appen A, Ladinsky MS, Redd MJ, Nikolova L, Bjorkman PJ, Sundquist WI, Ullman KS, Frost A
Proceedings of the National Academy of Sciences of the United States of America114(11)E2166-E2175(2017 Mar)

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Vietri M, Schink KO, Campsteijn C, Wegner CS, Schultz SW, Christ L, Thoresen SB, Brech A, Raiborg C, Stenmark H
Nature522(7555)231-5(2015 Jun)

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
Cashikar AG, Shim S, Roth R, Maldazys MR, Heuser JE, Hanson PI
eLife3(2014 May)

ESCRT requirements for EIAV budding.
Sandrin V, Sundquist WI
Retrovirology10104(2013 Oct)

ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding.
Effantin G, Dordor A, Sandrin V, Martinelli N, Sundquist WI, Schoehn G, Weissenhorn W
Cellular microbiology15(2)213-26(2013 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Chmp2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Chmp2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa08611 NM_001108906.1
Latest version!		 Rattus norvegicus charged multivesicular body protein 2A (Chmp2a), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
ORa08611 XM_006228118.2
Latest version!		 Rattus norvegicus charged multivesicular body protein 2A (Chmp2a), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
ORa22273 XM_006228117.2
Latest version!		 Rattus norvegicus charged multivesicular body protein 2A (Chmp2a), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa08611
Clone ID Related Accession (Same CDS sequence) XM_006228118.2 , NM_001108906.1
Accession Version NM_001108906.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 669bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2018-05-27
Organism Rattus norvegicus(Norway rat)
Product charged multivesicular body protein 2a
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH474090.1. On or before Oct 4, 2007 this sequence version replaced XM_344860.3, XM_001055138.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: FQ231086.1, FQ232385.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AAAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCAGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG CGATATGTGC GCAAGTTTGT GTTGATGCGG 
GCCAATATCC AGGCTGTGTC CCTCAAGATA CAAACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACCATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGATGCCAT TGATGATGCA ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT ACTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTCCCCT CCACTGGAGG CTCACTCAGT GTGGCTGCTG GCGGAAAGAA AGCAGAGGCC 
ACAGCCTCAG CTCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001102376.1
CDS175..843
Translation

Target ORF information:

RefSeq Version NM_001108906.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus charged multivesicular body protein 2A (Chmp2a), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001108906.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AAAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCAGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG CGATATGTGC GCAAGTTTGT GTTGATGCGG 
GCCAATATCC AGGCTGTGTC CCTCAAGATA CAAACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACCATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGATGCCAT TGATGATGCA ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT ACTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTCCCCT CCACTGGAGG CTCACTCAGT GTGGCTGCTG GCGGAAAGAA AGCAGAGGCC 
ACAGCCTCAG CTCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa08611
Clone ID Related Accession (Same CDS sequence) XM_006228118.2 , NM_001108906.1
Accession Version XM_006228118.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 669bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product charged multivesicular body protein 2a isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228118.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AAAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCAGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG CGATATGTGC GCAAGTTTGT GTTGATGCGG 
GCCAATATCC AGGCTGTGTC CCTCAAGATA CAAACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACCATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGATGCCAT TGATGATGCA ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT ACTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTCCCCT CCACTGGAGG CTCACTCAGT GTGGCTGCTG GCGGAAAGAA AGCAGAGGCC 
ACAGCCTCAG CTCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006228180.1
CDS174..842
Translation

Target ORF information:

RefSeq Version XM_006228118.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus charged multivesicular body protein 2A (Chmp2a), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006228118.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AAAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCAGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG CGATATGTGC GCAAGTTTGT GTTGATGCGG 
GCCAATATCC AGGCTGTGTC CCTCAAGATA CAAACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACCATGA ACAGACAGCT GAAATTACCC 
CAGATCCAGA AGATCATGAT GGAGTTTGAA CGGCAGGCAG AGATCATGGA CATGAAGGAA 
GAAATGATGA ATGATGCCAT TGATGATGCA ATGGGTGATG AGGAAGATGA AGAGGAGAGT 
GATGCTGTTG TGTCCCAGGT ACTGGATGAG CTGGGACTGA GCCTCACAGA TGAGCTGTCA 
AACCTCCCCT CCACTGGAGG CTCACTCAGT GTGGCTGCTG GCGGAAAGAA AGCAGAGGCC 
ACAGCCTCAG CTCTGGCTGA TGCTGATGCA GACCTGGAAG AGAGGCTCAA GAACCTTCGC 
AGGGACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa22273
Clone ID Related Accession (Same CDS sequence) XM_006228117.2
Accession Version XM_006228117.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 744bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product charged multivesicular body protein 2a isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228117.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AAAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCAGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG CGATATGTGC GCAAGTTTGT GTTGATGCGG 
GCCAATATCC AGGCTGTGTC CCTCAAGATA CAAACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACCATGA ACAGACAGGT TTGTCCCTCC 
CAATCCACTT TCCCATCCCC ATTGACCTTC AGGCAGGTCA CTCACCCTCC CTGCTTCTTC 
CAGCTGAAAT TACCCCAGAT CCAGAAGATC ATGATGGAGT TTGAACGGCA GGCAGAGATC 
ATGGACATGA AGGAAGAAAT GATGAATGAT GCCATTGATG ATGCAATGGG TGATGAGGAA 
GATGAAGAGG AGAGTGATGC TGTTGTGTCC CAGGTACTGG ATGAGCTGGG ACTGAGCCTC 
ACAGATGAGC TGTCAAACCT CCCCTCCACT GGAGGCTCAC TCAGTGTGGC TGCTGGCGGA 
AAGAAAGCAG AGGCCACAGC CTCAGCTCTG GCTGATGCTG ATGCAGACCT GGAAGAGAGG 
CTCAAGAACC TTCGCAGGGA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006228179.1
CDS557..1300
Translation

Target ORF information:

RefSeq Version XM_006228117.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus charged multivesicular body protein 2A (Chmp2a), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006228117.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
ATGGACCTGT TGTTTGGGCG CCGGAAGACG CCAGAGGAAC TACTTCGGCA AAACCAGAGG 
GCCCTGAACC GAGCCATGAG AGAACTGGAC AGGGAACGAC AAAAACTAGA AACCCAGGAA 
AAGAAAATCA TTGCAGACAT CAAAAAGATG GCAAAGCAAG GCCAGATGGA TGCTGTTCGA 
ATCATGGCAA AAGACCTGGT GCGTACCCGG CGATATGTGC GCAAGTTTGT GTTGATGCGG 
GCCAATATCC AGGCTGTGTC CCTCAAGATA CAAACTCTAA AATCCAACAA CTCAATGGCA 
CAAGCCATGA AGGGTGTTAC TAAGGCCATG GGCACCATGA ACAGACAGGT TTGTCCCTCC 
CAATCCACTT TCCCATCCCC ATTGACCTTC AGGCAGGTCA CTCACCCTCC CTGCTTCTTC 
CAGCTGAAAT TACCCCAGAT CCAGAAGATC ATGATGGAGT TTGAACGGCA GGCAGAGATC 
ATGGACATGA AGGAAGAAAT GATGAATGAT GCCATTGATG ATGCAATGGG TGATGAGGAA 
GATGAAGAGG AGAGTGATGC TGTTGTGTCC CAGGTACTGG ATGAGCTGGG ACTGAGCCTC 
ACAGATGAGC TGTCAAACCT CCCCTCCACT GGAGGCTCAC TCAGTGTGGC TGCTGGCGGA 
AAGAAAGCAG AGGCCACAGC CTCAGCTCTG GCTGATGCTG ATGCAGACCT GGAAGAGAGG 
CTCAAGAACC TTCGCAGGGA CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells.
Proceedings of the National Academy of Sciences of the United States of America114(11)E2166-E2175(2017 Mar)
Gu M,LaJoie D,Chen OS,von Appen A,Ladinsky MS,Redd MJ,Nikolova L,Bjorkman PJ,Sundquist WI,Ullman KS,Frost A


book

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.
Nature522(7555)231-5(2015 Jun)
Vietri M,Schink KO,Campsteijn C,Wegner CS,Schultz SW,Christ L,Thoresen SB,Brech A,Raiborg C,Stenmark H


book

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.
eLife3(2014 May)
Cashikar AG,Shim S,Roth R,Maldazys MR,Heuser JE,Hanson PI


book

ESCRT requirements for EIAV budding.
Retrovirology10104(2013 Oct)
Sandrin V,Sundquist WI


book

ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding.
Cellular microbiology15(2)213-26(2013 Feb)
Effantin G,Dordor A,Sandrin V,Martinelli N,Sundquist WI,Schoehn G,Weissenhorn W