Ufm1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Ufm1
Entrez Gene ID	365797
Full Name	ubiquitin-fold modifier 1
Synonyms	RGD1304890
General protein information	Preferred Names ubiquitin-fold modifier 1 Names ubiquitin-fold modifier 1
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q26

mRNA and Protein(s)

mRNA Protein Name

NM_001126080.2 NP_001119552.1 ubiquitin-fold modifier 1 precursor
Pathways from BioSystems

mRNA	Protein	Name
NM_001126080.2	NP_001119552.1	ubiquitin-fold modifier 1 precursor

Homologies

Pan troglodytes (chimpanzee)	UFM1	XP_001149496.1
Rattus norvegicus (Norway rat)	Ufm1	NP_001119552.1
Bos taurus (cattle)	UFM1	NP_001039779.1
Anopheles gambiae (African malaria mosquito)	UFM1_ANOGA	XP_321781.3
Arabidopsis thaliana (thale cress)	AT1G77710	NP_177894.1
Xenopus tropicalis (tropical clawed frog)	ufm1	NP_001016988.1
	UFM1	XP_001086251.1
Canis lupus familiaris (dog)	UFM1	XP_534489.3
Homo sapiens (human)	UFM1	NP_057701.1
Gallus gallus (chicken)	UFM1	NP_001025998.1
Danio rerio (zebrafish)	ufm1	NP_997792.1
Caenorhabditis elegans (roundworm)	tag-277	NP_498705.1
Mus musculus (house mouse)	Ufm1	NP_080711.1
Drosophila melanogaster (fruit fly)	CG34191	NP_001097354.1
Oryza sativa (rice)	Os01g0962400	NP_001045478.1

Gene Ontology
Bibliography

Related articles in PubMed

Modification of ASC1 by UFM1 is crucial for ER? transactivation and breast cancer development.
Yoo HM, Kang SH, Kim JY, Lee JE, Seong MW, Lee SW, Ka SH, Sou YS, Komatsu M, Tanaka K, Lee ST, Noh DY, Baek SH, Jeon YJ, Chung CH
Molecular cell56(2)261-74(2014 Oct)

Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
Zhang Y, Zhang M, Wu J, Lei G, Li H
PloS one7(11)e48587(2012)

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.
Lemaire K, Moura RF, Granvik M, Igoillo-Esteve M, Hohmeier HE, Hendrickx N, Newgard CB, Waelkens E, Cnop M, Schuit F
PloS one6(4)e18517(2011 Apr)

A novel type of E3 ligase for the Ufm1 conjugation system.
Tatsumi K, Sou YS, Tada N, Nakamura E, Iemura S, Natsume T, Kang SH, Chung CH, Kasahara M, Kominami E, Yamamoto M, Tanaka K, Komatsu M
The Journal of biological chemistry285(8)5417-27(2010 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Ufm1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ufm1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa01278	NM_001126080.2 Latest version!	Rattus norvegicus ubiquitin-fold modifier 1 (Ufm1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Ufm1 ( NM_001126080.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001119552.1 Rattus norvegicus ubiquitin-fold modifier 1 (Ufm1), mRNA.

Price & Availability↑

CloneID	ORa01278
Clone ID Related Accession (Same CDS sequence)	NM_001126080.2
Accession Version	NM_001126080.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 258bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-03
Organism	Rattus norvegicus(Norway rat)
Product	ubiquitin-fold modifier 1 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CB787557.1, CV112030.1, FM099369.1, FM094134.1, BP500691.1 and BQ780192.1. On Nov 25, 2010 this sequence version replaced NM_001126080.1. ##Evidence-Data-START## Transcript exon combination :: CB787557.1, FQ229705.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCGAAGG TGTCCTTTAA AATCACGCTG ACGTCGGACC CGCGGCTACC GTACAAAGTC 
CTCAGCGTTC CTGAAAGCAC ACCTTTCACA GCTGTGCTAA AGTTTGCAGC AGAAGAGTTT 
AAAGTTCCTG CTGCTACAAG TGCGATTATT ACTAATGATG GAATAGGAAT TAATCCTGCA 
CAGACTGCTG GAAACGTTTT TCTGAAGCAC GGCTCAGAGC TGCGGCTCAT TCCTCGAGAC 
CGAGTTGGGA GCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001119552.1
CDS	85..342
Translation	MSKVSFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRLIPRDRVGSC

Target ORF information:

RefSeq Version	NM_001126080.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus ubiquitin-fold modifier 1 (Ufm1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001126080.2

ORF Insert Sequence:

ATGTCGAAGG TGTCCTTTAA AATCACGCTG ACGTCGGACC CGCGGCTACC GTACAAAGTC 
CTCAGCGTTC CTGAAAGCAC ACCTTTCACA GCTGTGCTAA AGTTTGCAGC AGAAGAGTTT 
AAAGTTCCTG CTGCTACAAG TGCGATTATT ACTAATGATG GAATAGGAAT TAATCCTGCA 
CAGACTGCTG GAAACGTTTT TCTGAAGCAC GGCTCAGAGC TGCGGCTCAT TCCTCGAGAC 
CGAGTTGGGA GCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Modification of ASC1 by UFM1 is crucial for ER? transactivation and breast cancer development.
Molecular cell56(2)261-74(2014 Oct)
Yoo HM,Kang SH,Kim JY,Lee JE,Seong MW,Lee SW,Ka SH,Sou YS,Komatsu M,Tanaka K,Lee ST,Noh DY,Baek SH,Jeon YJ,Chung CH

Transcriptional regulation of the Ufm1 conjugation system in response to disturbance of the endoplasmic reticulum homeostasis and inhibition of vesicle trafficking.
PloS one7(11)e48587(2012)
Zhang Y,Zhang M,Wu J,Lei G,Li H

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.
PloS one6(4)e18517(2011 Apr)
Lemaire K,Moura RF,Granvik M,Igoillo-Esteve M,Hohmeier HE,Hendrickx N,Newgard CB,Waelkens E,Cnop M,Schuit F

A novel type of E3 ligase for the Ufm1 conjugation system.
The Journal of biological chemistry285(8)5417-27(2010 Feb)
Tatsumi K,Sou YS,Tada N,Nakamura E,Iemura S,Natsume T,Kang SH,Chung CH,Kasahara M,Kominami E,Yamamoto M,Tanaka K,Komatsu M

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Ufm1 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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