Gene Symbol | Dnmt3b |
Entrez Gene ID | 444985 |
Full Name | DNA methyltransferase 3 beta |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Dnmt3b cDNA ORF clone
Gene Symbol | Dnmt3b |
Entrez Gene ID | 444985 |
Full Name | DNA methyltransferase 3 beta |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001003959.1 | NP_001003959.1 | DNA (cytosine-5)-methyltransferase 3B |
Homo sapiens (human) | DNMT3B | NP_008823.1 |
Pan troglodytes (chimpanzee) | DNMT3B | XP_514580.3 |
Canis lupus familiaris (dog) | DNMT3B | XP_003433293.1 |
Bos taurus (cattle) | LOC100848415 | XP_003586886.2 |
Mus musculus (house mouse) | Dnmt3b | NP_001116469.1 |
Rattus norvegicus (Norway rat) | Dnmt3b | NP_001003959.1 |
Gallus gallus (chicken) | DNMT3B | NP_001019999.1 |
Danio rerio (zebrafish) | dnmt4 | NP_001020621.1 |
DNMT3B | XP_001107440.2 |
The DNA methyltransferase DNMT3C protects male germ cells from transposon activity.
Barau J, Teissandier A, Zamudio N, Roy S, Nalesso V, H?rault Y, Guillou F, Bourc'his D
Science (New York, N.Y.)354(6314)909-912(2016 11)
DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model.
Valencia Ant?nez CA, Taja Chayeb L, Rodr?guez-Segura M?, L?pez ?lvarez GS, Garc?a-Cu?llar CM, Villa Trevi?o S
Oncology reports32(5)2093-103(2014 Nov)
Epigenetic regulation of acute inflammatory pain.
Abzianidze E, Kvaratskhelia E, Tkemaladze T, Kankava K, Gurtskaia G, Tsagareli M
Georgian medical news(235)78-81(2014 Oct)
Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis.
Ping J, Wang JF, Liu L, Yan YE, Liu F, Lei YY, Wang H
Toxicology32153-61(2014 Jul)
Playing TETris with DNA modifications.
Delatte B, Deplus R, Fuks F
The EMBO journal33(11)1198-211(2014 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The authors developed a resistant hepatocyte rat model of liver carcinogenesis showing underexpression of DNMT3a and DNMT3b during the early stages.
Title: DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model.
We have found that during acute inflammatory pain induced by the application of 10% mustard oil on the tongues of rats, levels of DNMT3a and 3b were elevated markedly
Title: Epigenetic regulation of acute inflammatory pain.
High resveratrol downregulated DNMT3b and upregulated primarily tumor suppressive miRNAs in hormone sensitive mammary tumors, but not in matched normal mammary tissue.
Title: Methylation and miRNA effects of resveratrol on mammary tumors vs. normal tissue.
A novel role of T-Cad in the NGF-mediated differentiation of PC12 cells to neuronal phenotype associated with Dnmt3b regulation is reported.
Title: Identification of T-cadherin as a novel target of DNA methyltransferase 3B and its role in the suppression of nerve growth factor-mediated neurite outgrowth in PC12 cells.
Data show that DNA methyltransferase 3b (Dnmt3b)-mediated neuronal differentiation is due to its recruitment of histone deacetylase 2 (Hdac2).
Title: DNA methyltransferase 3b regulates nerve growth factor-induced differentiation of PC12 cells by recruiting histone deacetylase 2.
The following Dnmt3b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dnmt3b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa26555 | |
Clone ID Related Accession (Same CDS sequence) | NM_001003959.1 | |
Accession Version | NM_001003959.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2580bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-07-20 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | DNA (cytosine-5)-methyltransferase 3B | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BN000397.1. On Apr 19, 2005 this sequence version replaced XM_579109.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BN000397.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGAAGGGAG ACAGCAGACA TCTTAATGAA GAAGAGGGTG CTAGTGGGTA TGAGGACTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001003959.1 |
CDS | 409..2988 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001003959.1 |
1 | ATGAAGGGAG ACAGCAGACA TCTTAATGAA GAAGAGGGTG CTAGTGGGTA TGAGGACTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The DNA methyltransferase DNMT3C protects male germ cells from transposon activity. |
DNA methyltransferases 3a and 3b are differentially expressed in the early stages of a rat liver carcinogenesis model. |
Epigenetic regulation of acute inflammatory pain. |
Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis. |
Playing TETris with DNA modifications. |